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Pramipexole Dihydrochloride Monohydrate CAS 191217-81-9 White Pharmaceutical Raw Materials for Treating Parkinson

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Pramipexole Dihydrochloride Monohydrate CAS 191217-81-9 White Pharmaceutical Raw Materials for Treating Parkinson

China Pramipexole Dihydrochloride Monohydrate CAS 191217-81-9 White Pharmaceutical Raw Materials for Treating Parkinson supplier
Pramipexole Dihydrochloride Monohydrate CAS 191217-81-9 White Pharmaceutical Raw Materials for Treating Parkinson supplier Pramipexole Dihydrochloride Monohydrate CAS 191217-81-9 White Pharmaceutical Raw Materials for Treating Parkinson supplier

Large Image :  Pramipexole Dihydrochloride Monohydrate CAS 191217-81-9 White Pharmaceutical Raw Materials for Treating Parkinson

Product Details:

Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: CAS: 191217-81-9

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Minimum Order Quantity: 10g
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Detailed Product Description
Product Name: Pramipexole Dihydrochloride Monohydrate Purity: 99%
CAS: 191217-81-9 MF: C10H21Cl2N3OS
MW: 302.26 Appearance: White Powder

White Pharmaceutical Raw Materials Powder Pramipexole Dihydrochloride Monohydrate CAS 191217-81-9 for Treating Parkinson

 

Product Name: Pramipexole Dihydrochloride Monohydrate

 

Product Details:

 

 

Product Name

 

Pramipexole

Alias

Mirapex;(S)-2-Amino-6-(propylamino)-4,5,6,7-tetrahydrobenzothiazol tetrahydrobenzothiazol; Mirapex,Sifrol,Mirapexin;Pramipexole dihydrochloride monohydrate;(6S)-N'-Propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine hydrate dihydrochloride;(S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride monohydrate;Pramipexole;

 

CAS 

 

191217-81-9

 

MF

 

C10H21Cl2N3OS

 

MW

 

302.26

 

Purity

 

99%

 

Boiling Point

 

378ºC at 760 mmHg

 

Flash Point

 

182.4ºC

 

Loss on drying

 

NMT 0.5%

 

Residue on ignition

 

NMT 0.5%

 

Appearance

 

White Powder

 

Certification

 

ISO 9001, USP, BP

 

Standard

 

USP Standard

Usage

It is sometimes used off-label as a treatment for cluster headache and to counteract the problems with sexual dysfunction experienced by some users of the selective serotonin reuptake inhibitor (SSRI) antidepressants.

 

Storage

 

Store in cool and dry area and keep away from direct sunlight

 

 

Description:

 

Pramipexole is a dopamine agonist belonging to the same class of drugs as Cabergoline. The primary purpose of this drug is in the treatment of Parkinson's disease. Pramipexole is most commonly found under the brand names Sifrol, Mirapexin and Mirapex, although generics are also available. Mirapex is the most well known brand by Boehringer Ingelheim Pharmaceuticals. Along with treating Parkinson's, Pramipexole is also prescribed for the treatment of restless legs syndrome. The drug has also shown promising signs in the treatment of bipolar depression, although it has never officially held this label.
Pramipexole is a non-ergoline dopamine agonist indicated for treating early-stage Parkinson's disease (PD) and restless legs syndrome (RLS).It is also sometimes used off-label as a treatment for cluster headache and to counteract the problems with sexual dysfunction experienced by some users of the selective serotonin reuptake inhibitor (SSRI) antidepressants. Pramipexole has shown robust effects on pilot studies in a placebo-controlled proof of concept study in bipolar disorder. It is also being investigated for the treatment of clinical depression and fibromyalgia.

 

 

Application:

 

To alleviate the symptoms of Parkinson's disease: Parkinson's disease is due to the movement of brain dopaminergic neuron loss caused by dopamine deficiency, lead to patients with tremor, rigidity and bradykinesia and a series of symptoms. Hydrochloric acid highly selective effects on dopamine D2 and D3 receptor agonist, dopamine release, improve motor symptoms. Research on Shannon display, early Parkinson's disease patients pramipexole monotherapy after, can effectively control the motor symptoms in patients with early stage, to help maintain the ability of daily life. Pramipexole in combination with levodopa can effectively improve the ADL score and motor symptoms in patients with advanced Parkinson's disease score in patients with advanced Parkinson's disease, make life more vibrant.

Pramipexole is a dopamine agonist that directly correlates with the prolactin hormone. As dopamine levels in the body go up, prolactin levels go down. It does this by having a direct effect on the dopamine D3 receptor. Although it also acts on the D2 receptor its affinity for the D3 receptor is seven times greater than any existing dopamine agonist. The effect of Pramipexole on the D3 receptor has a strong impact on the neurological system, which is why it's used to treat Parkinson's disease and in some cases Alzheimer's disease. Through acting on the D3 receptor, Pramipexole also affects a man's sexual interest and activity.
Prolactin is in part directly responsible for a man's refractory period, which refers to the time it takes to recover from sexual activity so that performance can occur again. By lowering prolactin through an increase in dopamine, Pramipexole can directly reduce the refractory period resulting in the ability to perform sexually more frequently. Treating the signs and symptoms of Parkinson disease. It is also used to treat restless legs syndrome (RLS). It may also be used for other conditions as determined by your doctor. Pramipexole is a dopamine agonist. Exactly how pramipexole works is not known. It may increase the action of certain chemical receptors in the brain.

 

 

 

Pramipexole Dihydrochloride Monohydrate CAS 191217-81-9 White Pharmaceutical Raw Materials for Treating Parkinson

 

 

Our Company Advantages:

 

1, High quality with competitive price:

1) Standard: U.S Standard
2) All Purity≥99.8%
3) We are manufacturer and can provide high quality products with factory price.


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1) Parcel can be sent out within 8 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99.8%
4)We provide re-ship policy.
5) We have warehouse in Australia, Canada and England, we have large amounts of stock in the warehouse, can ship to you directly from our foreign warehouse!
3, We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

 

 

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