|Place of Origin:||CHINA|
|Certification:||GMP , ISO 9001:2008|
|Model Number:||CAS: 140703-51-1|
|Minimum Order Quantity:||10g|
|Packaging Details:||Stealth And Discreet Packaging|
|Delivery Time:||Within 7 Working Days|
|Payment Terms:||Bank Transfer - Bitcoin - Western Union - MoneyGram|
|Supply Ability:||1kg per day|
|Appearance:||White Powder||Specification:||2 Mg/vial|
|Shipping Method:||EMS, HKEMS, FEDEX, DHL, UPS, Aramex, ETC||Product Name:||Hexarelin|
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Hexarelin (or just HEX) is a hormones peptide which contains a short chain made from just six amino acids and has structure similar to regulatory proteins which helps them to release G-hormone. Its molecular weight/mass is 877.05 and its molecular formula is C47H58N12O6. Clinical studies and trials with different peptides which release hormones have started in early 1990s, with study LED by scientist Denghenghi in which hexarelin was created by substituting one of amino acids in protein's structure by more stable form.
In 1995 another study took place in which its action on hypothalamus and pituitary gland was revealed. At the moment there are few ongoing studies regarding hexarelin features. The primal action of hexarelin is the stimulation of glands to release hormone of growth; However it also has positive effects on muscular endurance and can increase muscle strength and promote growth of muscular tissues. As well this peptide possesses some neuroprotective features alongside with participating in healing processes.
Ghrelin is an appetite-regulating factor secreted from peripheral organs that is involved in regulation of energy homoeostasis via binding to the receptor resulting in the secretion of by the pituitary gland. The pathway activated by binding of ghrelin to the secretagogue receptor, GHSR1a, regulates the activation of the downstream mitogen-activated protein kinase, Akt, nitric oxide synthase, and AMPK cascades in different cellular systems.
One of the important features of GHSR1a displays constitutive activity possessing basal activity in the absence of an agonist, resulting in a high degree of receptor internalization as well as of signaling activity. Inverse agonists for the ghrelin receptor could be particularly interesting for the treatment of obesity. This activity seems to provide a tonic signal required for the development of normal height, probably through an effect on the GH axis.
How Does It Work?
When Hexarelin is given as a subcutaneous injection, it activates the pituitary via a pulse, just like GHRP-6, and helps circulate growth hormone in the body. Unlike GHRP-6, it does not induce any hunger side effects.
Hexarelin has the ability to not only raise the level of GH in the body but to also suppress somatostatin, which is the main culprit that inhibits GH from being released. This means that there will be more GH in abundance. In addition, hexarelin is the strongest GHRP available, so users should notice that desensitization can come much quicker than other GHRP's.
This makes it less ideal for long term use, but with hexarelin's ability to raise healthy levels of IGF-1 and GH it can work perfect as a PCT tool for those coming off a synthetic GH/IGF-1 cycle. The potency of this peptide should not be underestimated and it comes with an increase in cortisol production as well as prolactin. Nothing close to what might be seen in elevated levels from steroid use, but compared to other GHRP's it has the strongest affinity to raise cortisol/prolactin.
Interestingly, the most amazing finding with hexarelin was its ability to act on cardiac receptors
separate from the GH releasing properties. The peptide can directly aid in cardio protective left
ventricular pressure issues, as well as, help healing scar tissue on the heart. Studies on lean and
obese lab rats concluded that while lean rats were able to take advantage of the GH plasma
increase better than the obese rats (the healthier the rat the more hexarelin effectively produced
and utilized GH), obese rats did not see the same advantage. Separate from the studies that
monitored GH, both lean and obese rats both received all of the cardio protective properties of
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