Articaine HCL Local Anesthetic Powder CAS 23964-57-0 99% High Purity

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: 23964-57-0
Minimum Order Quantity: Negotiation
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Packaging Details: Stealth And Discreet Packaging
Delivery Time: Within 7 Working Days
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Supply Ability: 100 KG/Month
Product Name: Articaine HCL CAS: 23964-57-0
Appearance: White Powder Usage: Pain Killer
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pure benzocaine powder

Articaine HCL Local Anesthetic Powder CAS 23964-57-0 99% High Purity 0

 

Articaine hydrochloride

 

 

Articaine hydrochloride

 

Articaine HCL Local Anesthetic Powder CAS 23964-57-0 99% High Purity 1
 

CAS:23964-57-0

MF:C13H20N2O3S.ClH

MW:320.839

EINECS:245-957-7

Synonyms:methyl 4-methyl-3-[[(1-oxo-2-(propylamino)propyl]amino]-2-thenoate monohydrochloride ;CarticaineHCl;Ultracaine;CARTICAINE HYDROCHLORIDE;Ultracain;Articaine hydrochloride;Methyl 4-methyl-3-(2-propylaminopropanoylamino)thiophene-2-carboxylate hydrochloride;4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylic acid methyl ester hydrochloride

 
 
Properties
 

Melting point:177-178°

storage temp. 2-8°C

solubility H2O: soluble20mg/mL, clear

color white to beige

 

 

Description


Articaine hydrochloride , its CAS NO. is 23964-57-0, the synonyms are 2-Thiophenecarboxylic acid,4-methyl-3-((1-oxo-2-(propylamino)propyl)amino)-, methyl ester, monohydrochloride ; 4-Methyl-3-(2-(propylamino)propionamido)-2

thiophenecarboxylic acid methyl ester HCl ; Articaine HCl ; Methyl4-methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylate, monohydrochloride ; Septanest ; Septocaine .Articaine is a dental local anesthetic. It is the most widely used local anesthetic in a number of European countries and is available in many countries around the world.

Structure and metabolism: The amide structure of articaine is similar to that of other local anesthetics, but its molecular structure differs through the presence of a thiophene ring instead of a benzene ring. Articaine is exceptional because it contains an additional ester group that is metabolized by esterases in blood and tissue. The elimination of articaine is exponential with a half-life of 20 minutes. Since articaine is hydrolized very quickly in the blood, the risk of systemic intoxication seems to be lower than with other anesthetics, especially if repeated injection is performed.

 


Application

Articaine is a local anaesthetic that has been approved overseas for several years. Like other amide anaesthetics, articaine blocks nerve conduction when it is infiltrated around a nerve. This action is prolonged by combining the drug with a vasoconstrictor


Clinical use


(1) Articaine is used for pain control. Like other local anesthetic drugs, articaine causes a transient
and completely reversible state of anesthesia (loss of sensation) during (dental) procedures.


(2) In dentistry, articaine is used both for infiltration and block injections, with the block technique
yielding the greatest duration of anesthesia.


(3) In people with hypokalemic sensory overstimulation, lidocaine is not very effective, but articaine
works well.

 

 

Usage and Dosage


Local infiltration or nerve block anesthesia, oral submucosal injection.Before pumping the blood back to check whether the blood vessels,especially nerve block anesthesia.The injection rate should not exceed 1 ml/min.Adults:The appropriate dose must be administered according to the needs of the operation.For general surgery,usually given dose of 1/2 to 1 or compliance.The maximum dose of articaine hydrochloride should not exceed 7 mg/kg body weight.Children over 4 years of age: different doses must be used depending on the age,weight,and type of operation of the child.The maximum dose of articaine hydrochloride does not exceed 5 mg/kg body weight.The average dose for children receiving orally taking orally is calculated in milligrams as follows:Weight of child (kg) x1.33 Older:Half of adult dose.
 

 

 

Local Anesthetic Powder

 

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