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Avanafil Male Enhancement Steroids Raw Powder Male Sexual Dysfunction Treatment CAS 330784-47-9

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Avanafil Male Enhancement Steroids Raw Powder Male Sexual Dysfunction Treatment CAS 330784-47-9

Avanafil Male Enhancement Steroids Raw Powder Male Sexual Dysfunction Treatment CAS 330784-47-9
Avanafil Male Enhancement Steroids Raw Powder Male Sexual Dysfunction Treatment CAS 330784-47-9 Avanafil Male Enhancement Steroids Raw Powder Male Sexual Dysfunction Treatment CAS 330784-47-9

Large Image :  Avanafil Male Enhancement Steroids Raw Powder Male Sexual Dysfunction Treatment CAS 330784-47-9

Product Details:
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: CAS: 330784-47-9
Payment & Shipping Terms:
Minimum Order Quantity: 3g
Price: Contact Us
Packaging Details: Stealth And Discreet Packaging
Delivery Time: Within 7 Working Days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 10 KG/Month
Detailed Product Description
Product Name: Avanafil MF: C23H26ClN7O3
MW: 483.95 Melting Point: 163°C
Density: 1.372 Storage Temp: Refrigerator
Appearance: White Crystalline Powder
High Light:

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Description:

Avanafil is a PDE5 inhibitor approved for erectile dysfunction by FDA . Avanafil acts by inhibiting

 

a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily

 

in the corpus cavernosum penis, as well as the retina. Other similar drugs are tadalafil and

 

vardenafil. The advantage of avanafil is that it has very fast onset of action compared with other

 

PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 3045

 

minutes.

 

 

Usage:
 

It is a development of the phosphodiesterase type 5 inhibitors, for the treatment of male sexual

 

dysfunction, at present in the America, EU and Japan have completed phase II clinical trials,

 

phase III clinical trials will start. The product is composed of Japanese Tanabe Pharma Company

 

and VIVUS company development. In addition to oral dosage forms, VIVUS company is also

 

developing Avanafil urethral administration, for not responding to oral dosage forms of patients.
 

 

Avanafil is a potent, highly selective phosphodiesterase 5 inhibitor, in vitro experiments showed

 

that the selectivity of phosphodiesterase 5 stronger than sildenafil. The compound dear

 

compliance weak against other phosphodiesterase, and effect of adenosine receptor

 

decreased, suggesting that the cardiovascular effects of avanafil should be weaker than

 

sildenafil. Pre clinical study showed that avanafil and organic nitrate drugs taken in combination

 

to reduce its on blood pressure was significantly weaker than sildenafil and nitrate drugs with

 

clothes. Moreover, avanafil inhibition of phosphodiesterase 6 is very weak, the relevant visual

 

disturbance suppression may the enzyme phosphodiesterase 5 inhibitor induced and other.

 

 

Dosage :
 

For most individuals, the recommended starting dose of avanafil is 100 mg per day taken about

 

30 minutes before sexual activity. Depending on the adequacy of the response or side effects,

 

the dose may be increased to 200 mg or decreased to 50 mg a day. Individuals who are taking

 

medications that moderately increase the blood levels of avanafil should not exceed a total dose

 

of 50 mg in 24 hours.

 

 

Lab Test Result:

 

 

Product name

 

  Avanafil

 

CAS No.

 

330784-47-9

 

Packaging

 

1KG/Bag

 

Production date

 

2017/04/30

 

Shelf life

 

2019/04/29

 

Standard

 

  IHS

 

Items

 

Specification

 

Results

 

Description

 

white or off white crystalline powder

 

white crystalline powder

 

 

Solubility

 

soluble in dimethyl sulfoxide & slightly soluble in ethanol and methanol

 

 

complies

 

 

 

Identification,HPLC

 

the principal peak in the chromatogram obtained with test solution is corresponds to retention time the principal peak in the chromatogram obtained with RS in the assay

 

 

 

complies

 

Melting point

 

132-165℃

 

163℃

 

Heavy metals

 

not more than 10ppm

 

complies

 

Loss on drying

 

not more than 0.5%

 

0.248%

 

Specific optical rotation

 

-18.0 °to -26.0°

 

-25.06°

 

Methanol

 

NMT 3000ppm

 

complies

 

Chloroform

 

NMT 60ppm

 

complies

 

Sulphated ash

 

not more than 0.1%

 

0.05%

 

Assay

 

98-102%

 

99.811%

 

Conclusion

 

Qualified

 

 

Avanafil Male Enhancement Steroids Raw Powder Male Sexual Dysfunction Treatment CAS 330784-47-9 0

 

 

 

Sex Drug Raw Powder

 

 

 Sildenafil Citrate ()

 

 Vardenafil

 

 Tadalafil (Cialis)

 

 Vardenafil HCL

 

 

 

 Yohimbine HCL

 

  HCL

 

 Avanafil

 

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