CAS 129938-20-1 Sex Male Enhancement Powder Hydrochloride Pharmaceutical Intermediates

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: CAS: 129938-20-1
Minimum Order Quantity: 10g
Price: Contact Us
Packaging Details: Stealth and discreet packaging
Delivery Time: Usually within 7 work days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 5000kg/Month
CAS: 129938-20-1 Synonyms: HCL;Rimonabant 75000
MF: C9H7ClN2O5 MW: 258.62
Storage Temp: -20°C Freezer Appearance: Off-white Crystal
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Product Name:  hydrochloride

Product details:

 

Product Name hydrochloride
Alias DAPOXETIN;;(S-(+)-N,N-Dimethyl-a-[2-(naphthalenyloxy)ethyl]benzenemethanamine hydrochloride
CAS NO 129938-20-1
Appearance white powder.
MF C9H7ClN2O5
MW 258.62
Purity 99%min
Origin China
Export market Global
Grade Pharmaceutical grade
Supply capacity Mass in stock
Usage Pharmaceutical intermediates of

 

 

Description:


hydrochloride is an oral drug for the treatment of ED, used in the treatment of erectile dysfunction and premature ejaculation, erectile function impairment and premature ejaculation has very significant improvements.

There are over 1500 documents to prove the caused by different causes impotence premature ejaculation, knew the success rate is above 80%, and show its reliable curative effect, through the use of more than 20 million people worldwide, proved its long-term stability, the safety of 25 to 60 minutes of work function to coincide with a time needed for foreplay, knew the time adjustment in the highest drug concentration time, help both husband and wife a satisfactory sex life.

 

as a new fast SSRI, a short half life, a selective 5 - HT reuptake inhibitor (SSRI), for the treatment of premature ejaculation and erectile dysfunction. is a selective 5 - HT reuptake inhibitor (SSRI), such drugs widely used to treat depression and related affective disorders.
, marketed as (among and other brands) is the first compound developed specially for the treatment of premature ejaculation in men 18-64 years old. works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, and as a consequence promoting ejaculatory delay. As a member of selective serotonin reuptake inhibitor (SSRI) family, was initially created as an antidepressant. However, unlike other SSRIs, is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant.

 

 

Applications:


Treat male premature ejaculation and erectile dysfunction., marketed as (among and other brands) is the first compound developed specially for the treatment of premature ejaculation (PE) for men at th age of 18-64 years old. works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, so as to delay ejaculation.. As a member of selective serotonin reuptake inhibitor (SSRI) family, was initially created as an antidepressant. However, unlike other SSRIs, is absorbed and eliminated rapidly in the body. Its fast response makes it suitable for the treatment of PE but not as an antidepressant.


Due to the lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as Fluoxetine, Paroxetine, Sertraline, Fluvoxamine, and Citalopram have been used as clinical drugs to treat PE. Waldinger's meta analysis shows that the use of these conventional antidepressants increases IELT from two to nine times above base line in comparison of three to eight times when is used. However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug accumulation and as a consequence an increased adverse effects such as decreasing sexual libido and causing erectile dysfunction. , on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug's accumulation in the body, and therefore reducing side effects.

 

Treat male premature ejaculation and erectile dysfunction.
Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE.
Waldinger's meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when is used.However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug accumulation and as a consequence increased of adverse effects such as decreasing sexual libido and causing erectile dysfunction.
, on the other hand, is a fast-acting SSRI.It is rapidly absorbed and eliminated from the body within a few hours.This favorable pharmacokinetics minimizes the risk of the drug's accumulation in the body, and therefore reducing side effects.Pharmacodynamics

hydrochloride is a selective serotonin reuptake inhibitor. The physiology of ejaculation primarily depends on serotonin and dopamine receptors including 5-HT1a and 5-HT2c. hydrochloride prevents the reuptake of serotonin transporter. The drug binds with the reuptake transporters of norepinephrine and dopamine and inhibits the reuptake.

 

CAS 129938-20-1 Sex Male Enhancement Powder  Hydrochloride Pharmaceutical Intermediates 0

 

 

COA:

 

Items Specification Results
Assay ≥98.5% 99.3%
Melting Point 175.0~182.0℃ 178.6~179.8℃
Identification IR Conforms
Specific Rotation +128°±2(C=1,CH3OH) +127.2°
Lost on drying ≤1.0% 0.58%
Heavy Metals ≤10ppm Conforms
Residue on ignition ≤0.1% Conforms
Conclusion: Meet the requirement of House standard.

 

 

Dosage:

 

Initially, hydrochloride is given as a 30 mg tablet one to three hours before sexual intercourse. The dose may be increased by the prescribing doctor to 60 mg, depending on response and tolerance.

 

For premature ejaculation and erectile dysfunctions (Adults):The recommended adult dose of hydrochloride is 30 - 60 mg/day. The maximum dose should not exceed 100 mg/day. Take hydrochloride at least two hours before sexual intercourse to achieve maximum treatment benefits.

 

 

 

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