Cosmetic Raw Powder Material Powder Peptides SNAP-8(Acetyl Glutamyl Heptapeptide-3) CAS 868844-74-0 Anti Aging

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: CAS: 868844-74-0
Minimum Order Quantity: 10 vials
Price: Contact Us
Packaging Details: Stealth and discreet packaging
Delivery Time: Usually within 7 work days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 2000KG/Month
Product Name: Acetyl GlutaMyl Heptapeptide-3 CAS: 868844-74-0
MF: C41H70N16O16S MW: 1075.16
Other Name: SNAP-8 Appearance: White Powder
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Product Name: Acetyl GlutaMyl Heptapeptide-3

 

Product Details:


Synonyms: N-Acetyl-L-alpha-glutamyl-L-alpha-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-L-arginyl-L-alanyl-L-alpha-asparagine;SNAP-8(Acetyl Glutamyl Heptapeptide-3);N-Acetyl-L-alpha-glutamyl-L-alpha-glutamyl-L-methionyl-L-glutaminyl-L-arginyl-L-arginyl-L-alanyl-L-alpha-asparagine ;Acetyl GlutaMyl Octapeptide-3
CAS: 868844-74-0
MF: C41H70N16O16S
MW: 1075.16
Product Categories: Cosmetics beauty peptide
Appearance :White powder
Water Content(Karl Fischer) :≤5.0%
Acetate Content(by HPLC) :≤15.0%
Amino Acid Composition :±10% of theoretical
Purity (by HPLC) :≥95.0%
Single Impurity(by HPLC) :≤2.0%
Peptide Content(by %N ) :≥80%
Assay(By Anhydrous, Acetic Acid-free ) :95.0~105.0%
Bacterial Endotoxins :≤10EU/mg
Usage: anti-wrikle .SNAP-8 reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around the eyes.

 

 

Description:

 

The anti wrinkle octapeptide SNAP-8 is an elongation of the famous hexapeptide Argireline . SNAP-8 reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around the eyes.SNAP-8 is a mimic of the N-terminal end of SNAP-25 which competes with SNAP-25 for a position in the SNARE complex, thereby modulating its formation. If the SNARE complex is slightly destabilized, the vesicle can not release neurotransmitters efficiently and therefore muscle contraction is attenuated, preventing the formation of lines and wrinkles. Like Argireline, inhibits SNARE complex formation and catecholamine release, resulting in the reduction of the degree of existing facial wrinkles and demonstrated effectiveness against their development with regular use. In clinical studies, the severity of wrinkles around the eyes decreased up to 63.13%. Both in vivo and in vitro efficacy testing suggests that SNAP-8 is approximately 30% more active than its parent peptide Argireline. As supplied by the manufacturer, this product contains 0.05% SNAP-8 powder aka Acetyl Octapeptide-3.

SNAP-8 is a mimic of the N-terminal end of SNAP-25 which competes with SNAP-25 for a position in the SNARE complex, thereby modulating its formation. If the SNARE complex is slightly destabilized, the vesicle can not release neurotransmitters efficiently and therefore muscle contraction is attenuated, preventing the formation of lines and wrinkles. SNAP-8 is a safer, cheaper, and milder alternative to Botulinum Toxin, topically targeting the same wrinkle-formation mechanism in a very different way. SNAP-8 can be incorporated in cosmetic formulations such as emulsions, gels, and serums where attenuation of the deep lines or wrinkles in the forehead or around the eye are is desired.

 

 

Application:


The synthesis of SNAP-8 involves a final freeze-drying step. Freeze-dried products are commonly obtained as a polymorphous crystalline powder, which means that locally some aggregates and differences in crystal size may appear. This polymorphism is not associated to chemical differences and extensive work performed by the analytical department has ensured the homogeneity of the product. SNAP-8 is presented either as SNAP-8 Powder, an octapeptide in powder form which can be easily dissolved in water, or as SNAP-8 Solution, an aqueous solution containing 0.5 g/L of the powder version. It can be incorporated at the final stage of the manufacturing product, provided the temperature is below 40 degrees Celsius. Taking into consideration the concentration of peptide in SNAP-8 Solution, it is recommended that 3 to 10% of the solution is present in the final formulation in order to obtain significant anti-wrinkle activity.
SNAP-8 is a mimic of the N-terminal end of SNAP-25 which competes with SNAP-25 for a position in the SNARE complex, thereby modulating its formation. If the SNARE complex is slightly destabilized, the vesicle can not release neurotransmitters efficiently and therefore muscle contraction is attenuated, preventing the formation of lines and wrinkles
The anti wrinkle octapeptide SNAP-8 is an elongation of the famous hexapeptide Argireline. SNAP-8 reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around the eyes. SNAP-8 is a mimic of the N-terminal end of SNAP-25 which competes with SNAP-25 for a position in the SNARE complex, thereby modulating its formation. If the SNARE complex is slightly destabilized, the vesicle can not release neurotransmitters efficiently and therefore muscle contraction is attenuated, preventing the formation of lines and wrinkles. Like Argireline, inhibits SNARE complex formation and catecholamine release, resulting in the reduction of the degree of existing facial wrinkles and demonstrated effectiveness against their development with regular use. In clinical studies, the severity of wrinkles around the eyes decreased up to 63.13%. Both in vivo and in vitro efficacy testing suggests that SNAP-8 is approximately 30% more active than its parent peptide Argireline. As supplied by the manufacturer, this product contains 0.05% SNAP-8 powder aka Acetyl Octapeptide-3.


SNAP -8 is so named because it is an 8 member carbon chain which inhibits the SNAP complex from binding the vesicle. The 8 carbon end of the SNAP-25 is synthesized to make SNAP-8. This is like swapping the net out for a net with a huge hole. This inhibits the vesicle from binding to the membrane and discharging its contents into the neuromuscular junction. The result is a lack of muscular contraction. This lack of muscular contraction in facial muscles prevents the tonic pull on the skin and prevents new and alleviates old wrinkles.
SNAP-8 can be applied to the skin topically and has reduced wrinkles around the eyes and other parts of the face by up to 34%. SNAP-8 is cheaper and safer than BOTOX and works in the same way. SNAP-8 can be made into all types of topical preparations, from creams to gels or whatever you want, as long as the concentration is the right amount it will work. The maximum reduction for 10% SNAP-8 solution was 63% less wrinkles. SNAP-8 is a safer, cheaper, and milder alternative to Botulinum Toxin, topically targeting the same wrinkle-formation mechanism in a very different way. SNAP-8 can be incorporated in cosmetic formulations such as emulsions, gels, and serums where attenuation of the deep lines or wrinkles in the forehead or around the eye are is desired.

 

Cosmetic Raw Powder Material Powder Peptides SNAP-8(Acetyl Glutamyl Heptapeptide-3) CAS 868844-74-0 Anti Aging 0

 

 

Specification:

 

 

Item

 

Specification Result

 

Appearance

 

White powder Complies

 

Identification

 

Positive Complies

 

Assay

 

99.0% min 99.08%

 

Loss on Drying

 

6.0%max. 4.80%

 

Mass Balance

 

95.0~105.0% Complies

 

Acetate Content (HPIC)

 

12.0%max. 10.80%

 

Peptide Content (N%)

 

80.0%min. 88.00%

 

Amino Acid Composition

 

±10% of theoretical Complies

 

Single Impurity (HPLC)

 

1.0%max. 0.85%
 

 

 

Benefits:

 

1. Reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around the eyes.
2. A safer, cheaper, and milder alternative to Botulinum Toxin, topically targeting the same wrinkle-formation mechanism in a very different way.
3. Has been incorporated in cosmetic formulations such as emulsions, gels, sera, etc., where removal of the deep lines or wrinkles in the forehead or around the eyes area is desired.


 

Functions:

 

Scientific study based on animal test subjects has determined that the primary function of SNAP-8 is to act as a muscle contraction inhibitor. This act of inhibition allows for muscles to achieve a more consistent level of homeostasis, as it allows for the neurotransmitters that are responsible that are responsible for bringing about homeostasis to be released on a much more efficient basis.

SNAP-8 has been shown in research studies to be non-pharmaceutical topical alternative to Botox (Botulism Toxin). Research studies have shown that SNAP-8 is a safer, cheaper, and milder alternative to Botox (Botulisum Toxin). A topical alternative to Botox (Botulisum Toxin) targeting the same wrinkle-formation mechanism in a very different and much safer way. acetyl octapeptide-3 powder

 

 

Storage And Shelf Life:

 

SNAP-8 Powder and SNAP-8 Solution must be kept in a cool, dark and clean place to ensure a shelf life of at least twelve months. For long term storage it is recommended to store both forms at 4 ºC which extends shelf life to at least eighteen months. In rare cases, refrigerated storage of SNAP-8 Solution can cause precipitation of the preservative. This does not affect the integrity of the product.

 

 

Our Compamy Advantages:

 

1, High quality with competitive price:
1) Standard: U.S Standard
2) All Purity≥99.8%
3) We are manufacturer and can provide high quality products with factory price.


2, Fast and safe delivery
1) Parcel can be sent out within 8 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99.8%
4)We provide re-ship policy.
5) We have warehouse in Australia, Canada and England, we have large amounts of stock in the warehouse, can ship to you directly from our foreign warehouse!
3, We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

 

 

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