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Dexamethasone Acetate / Palmitate Raw Material For Medicine Manufacturing

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Dexamethasone Acetate / Palmitate Raw Material For Medicine Manufacturing

Dexamethasone Acetate / Palmitate Raw Material For Medicine Manufacturing
Dexamethasone Acetate / Palmitate Raw Material For Medicine Manufacturing

Large Image :  Dexamethasone Acetate / Palmitate Raw Material For Medicine Manufacturing

Product Details:
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: CAS: 50-02-2
Payment & Shipping Terms:
Minimum Order Quantity: 10g
Price: Contact Us
Packaging Details: Stealth And Discreet Packaging
Delivery Time: Within 7 Working Days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 2500 KG/Month
Detailed Product Description
Product Name: Dexamethasone MF: C22H29FO5
MW: 392.46 EINECS: 200-003-9
MP: 262-264 °C Appearance: White Solid
High Light:

pharmaceutical active ingredients

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pharmaceutical anabolic steroids

 

Dexamethasone & Dexamethasone-17-acetate & Dexamethasone Palmitate

 


Basic Details:

 

Product Name: Dexamethasone
 

Synonyms: Acidocont; Deronil; Dexacortal; dexametona; Flumeprednisolon
 

CAS: 50-02-2
 

MF: C22H29FO5
 

MW: 392.46
 

EINECS: 200-003-9
 

mp: 262-264 °C(lit.)
 

alpha: 75 °(c=1, dioxane)
 

refractive index: 76 ° (C=1, Dioxane)
 

storage temp: 2-8°C
 

solubility ethanol: 1 mg/mL
 

appearance: white solid
 

Water Solubility: 10 mg/100 mL (25°C)
 

Stability: Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, acid

 

anhydrides, acid chlorides. May be light sensitive

 

 

Application:
 

It is usually given by the inhaled route for direct effect on bronchial smooth muscle.This is usually

 

achieved through a metered dose inhaler (MDI), nebulizer or other proprietary delivery devices

 

(e.G.Rotahaler or Autohaler).In these forms of delivery, the maximal effect of salbutamol can take

 

place within five to 20 minutes of dosing, though some relief is immediately seen.It can also be

 

given intravenously.

 

Used in the treatment of bronchial asthma, asthmatic bronchitis, emphysema, patients

 

bronchospasm.

 

                                    Dexamethasone-17-acetate

 

 

Basic Details:

 

Product Name: Dexamethasone-17-acetate
 

Synonyms: Dexamethason Acetate
 

CAS: 1177-87-3
 

MF: C24H31FO6
 

MW: 434.5
 

EINECS: 214-646-8
 

mp: 238-240 °C(lit.)
 

refractive index: 87 °(C=1, Dioxane)
 

storage temp: 2-8°C
 

appearance: Off-White Solid

 

 

Application:
 

Dexamethasone-17-acetate, a corticosteroid, is similar to a natural hormone produced by your

 

adrenal glands. It often is used to replace this chemical when your body does not make enough of

 

it. It relieves inflammation (swelling, heat, redness, and pain) and is used to treat certain forms of

 

arthritis; skin, blood, kidney, eye, thyroid, and intestinal disorders; severe allergies; and asthma.

 

Dexamethasone-17-acetate is also used to treat certain types of cancer.
 

 

Dexamethasone-17-acetate comes as a tablet and a solution to take by mouth. Your doctor will

 

prescribe a dosing schedule that is best for you. Follow the directions on your prescription label

 

carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take

 

Dexamethasone-17-acetate exactly as directed. Do not take more or less of it or take it more

 

often than prescribed by your doctor.

 

 

Special Note:
 

Do not stop taking Dexamethasone-17-acetate without talking to your doctor. Stopping the drug

 

abruptly can cause loss of appetite, upset stomach, vomiting, drowsiness, confusion, headache,

 

fever, joint and muscle pain, peeling skin, and weight loss. If you take large doses for a long time,

 

your doctor probably will decrease your dose gradually to allow your body to adjust before

 

stopping the drug completely. Watch for these side effects if you are gradually decreasing your

 

dose and after you stop taking the tablets or oral liquid, even if you switch to an inhalation

 

corticosteroid medication. If these problems occur, call your doctor immediately. You may need to

 

increase your dose of tablets or liquid temporarily or start taking them again.

 

 

                                   Dexamethasone Palmitate

 

 

Basic Details:

 

Product Name: Dexamethasone palmitate
 

Synonyms: DXP;Limethason;Lipotalon
 

CAS: 14899-36-6
 

MF: C38H59FO6
 

MW: 630.87
 

mp: 60-65 °C
 

density: 1.12
 

storage temp: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
 

appearance: Colourless Thick Oil

 

 

Description:
 

Dexamethasone palmitate (DXP) is a lipophilic prodrug of dexamethasone (DXM), a potent

 

corticosteroide used to treat a variety of ophthalmic diseases. The aim of the study was to

 

characterize the sustained release capacity (in rabbit), efficacy (in rat and rabbit), and safety (in

 

rabbit, cat, and minipig) of intravitreal (IVT) DXP emulsions in preclinical models.

 

 

Application:
 

Oil-in-water emulsions of DXP were administered by IVT injections in rats, rabbits, cats, or

 

minipigs. Efficacy was assessed in rabbits by the inhibition of VEGF-induced vascular leakage

 

and in rats by inhibition of laser-induced choroidal neovascularization. Concentrations of DXP

 

and DXM in aqueous humor, vitreous, retina, choroid, and blood were determined to characterize

 

the ocular and systemic pharmacokinetic (PK) profile. Complete ophthalmic examinations

 

(indirect ophthalmoscopy, slit-lamp biomacroscopy, electroretinography, tonometry) were

 

performed to assess the ocular safety of IVT DXP doses up to 2,600 μg in minipig, followed by

 

histopathologic examinations. A validated feline model of DXM-induced elevated intraocular

 

pressure (IOP) was used to assess the ocular hypertensive impact (i.e., the safety) of an IVT

 

injection of DXP emulsion.

 

 

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