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Factory supply Best price Chinese Herbal Extract Anti-Cancer Indirubin / Folium Isatidis Extract By HPLC CAS 479-41-4

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Factory supply Best price Chinese Herbal Extract Anti-Cancer Indirubin / Folium Isatidis Extract By HPLC CAS 479-41-4

Factory supply Best price Chinese Herbal Extract Anti-Cancer Indirubin / Folium Isatidis Extract By HPLC CAS 479-41-4
Factory supply Best price Chinese Herbal Extract Anti-Cancer Indirubin / Folium Isatidis Extract By HPLC CAS 479-41-4 Factory supply Best price Chinese Herbal Extract Anti-Cancer Indirubin / Folium Isatidis Extract By HPLC CAS 479-41-4

Large Image :  Factory supply Best price Chinese Herbal Extract Anti-Cancer Indirubin / Folium Isatidis Extract By HPLC CAS 479-41-4

Product Details:
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: 479-41-4
Payment & Shipping Terms:
Minimum Order Quantity: Negotiation
Price: Contact Us
Packaging Details: Stealth And Discreet Packaging
Delivery Time: Within 7 Work Days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 100 KG/Month
Detailed Product Description
Product Name: Indirubin Other Name: Folium Isatidis Extract
CAS: 491-70-3 Appearance: Purple Pink Powder
Catagoty: Herbal Extract Shipping Method: EMS, HKEMS, FEDEX, DHL, UPS, Aramex, ETC
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Factory supply Best price Chinese Herbal Extract Anti-Cancer Indirubin / Folium Isatidis Extract By HPLC CAS 479-41-4

 

 

Indirubin

 

Factory supply Best price Chinese Herbal Extract Anti-Cancer Indirubin / Folium Isatidis Extract By HPLC CAS 479-41-4 0
 

CAS:479-41-4

MF:C16H10N2O2

MW:262.26

Synonyms:[2,3'-Biindolinylidene]-2',3-dione;Indirubin (Synthetic), >=98%;Indirubin/Folium Isatidis Extract;Isoindogotin;(delta(sup2,3’)-biindoline)-2’,3-dione ;3-(1,3-dihydro-3-oxo-2h-indol-2-ylidene)-1,3-dihydro-2h-indol-2-on ;c.i.73200 ;2-(2-oxo-1h-indol-3-ylidene)-1h-indol-3-one

 

 

Abstract

 

Indirubin is an active ingredient of anti-leukemia isolated from dried leaves of Isatis indigotica Fort. For the treatment of chronic myeloid leukemia, the total effective rate was 87.3%. In terms of reducing white blood cells effect, Indirubin is similar to Maryland, but better than Maryland in reducing liver. Its' blood and bone marrow mitigation effect is worse than Maryland, and has no cross tolenrance with Maryland.

Indirubin also has a certain effect on acute myeloid leukemia. It can be used for abnormal myelopathy and eosinophilia. Indirubin has inhibiting effect on a variety of transplanted animal tumors, and can destroy leukemia cells. With the effect of Indirubin, cells of degeneration and necrosis show swelling and soluble necrosis. Through experimental studies it is found that Indirubin can enhance the animal's monocyte-macrophage system's phagocytosis. Indirubin has no direct effect on protein synthesis. Its' inhibition of DNA synthesis is due to inhibition of DNA polymerase, affecting the polymerization of DNA. Indirubin metabolizes in liver and gallbladder after intravenous injection or intragastric administration. After 96 hours 76.03% Indirubin was eliminated by faeces. After taking this product, the mice's blood concentration gradually increased, after 12 hours it reached the peak, slowed down after a month, maintaining a long time. Indirubin is highly distributed in liver, gallbladder and gastrointestinal. Bioavailability was 46.48%.

 

 

Indication

 

Indirubin has anti-cancer effect. It is clinically used for the treatment of chronic myeloid leukemia.

 

 

Usage and Dosage

 

Adult Dosage: 50 ~ 300mg/day, generally 200mg/day, 3 to 4 times/day by taking orally until symptoms relieved or 3 months for a course of treatment.

 

 

Dosage From

 

Indirubin Tablet: 25mg; 50mg; 100mg.

 

 

 
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