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High Purity Local Anesthetic Powder Mepivacaine Hydrochloride / Mepivacaine HCL CAS 1722-62-9

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High Purity Local Anesthetic Powder Mepivacaine Hydrochloride / Mepivacaine HCL CAS 1722-62-9

High Purity Local Anesthetic Powder Mepivacaine Hydrochloride / Mepivacaine HCL CAS 1722-62-9
High Purity Local Anesthetic Powder Mepivacaine Hydrochloride / Mepivacaine HCL CAS 1722-62-9 High Purity Local Anesthetic Powder Mepivacaine Hydrochloride / Mepivacaine HCL CAS 1722-62-9

Large Image :  High Purity Local Anesthetic Powder Mepivacaine Hydrochloride / Mepivacaine HCL CAS 1722-62-9

Product Details:
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: 1722-62-9
Payment & Shipping Terms:
Minimum Order Quantity: Negotiation
Price: Contact Us
Packaging Details: Stealth And Discreet Packaging
Delivery Time: Within 7 Working Days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 100 KG/Month
Detailed Product Description
Product Name: Mepivacaine Hydrochloride Other Name: Mepivacaine HCL
MF: C15h22n2o.Clh MW: 282.81
Appearance: White Crystalline Powder Shipping Method: EMS, HKEMS, FEDEX, DHL, UPS, Aramex, ETC
High Light:

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High Purity Local Anesthetic Raw Powder Mepivacaine Hydrochloride / Mepivacaine HCL CAS 1722-62-9 For Pain Relieve

 

 

Abstract

Mepivacaine Hydrochloride, a tertiary amine used as a local anesthetic, is 1-methyl-2', 6' - pipecoloxylidide monohydrochloride.

A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route.

 


Pharmacodynamics

Mepivicaine is a local anesthetic of the amide type. Mepivicaine as a reasonably rapid onset and medium duration and is known by the proprietary names as Carbocaine and Polocaine. Mepivicaine is used in local infiltration and regional anesthesia. Systemic absorption of local anesthetics produces effects on the cardiovascular and central nervous systems. At blood concentrations achieved with normal therapeutic doses, changes in cardiac conduction, excitability, refractoriness, contractility, and peripheral vascular resistance are minimal.
 

 

COA

 

Product name Mepivacaine HCl
Appearance White crystalline powder
Assay (C13H20N2O2·HCl) 99.0% to 101.0% 99.50%
Melting point 153~158ºC 156.5~157.0ºC
Heavy metals ≤20ppm <5ppm
Acidity ≤0.02N NaOH 0.5ml 0.3ml
Chromatographic purity Secondary spots≤0.5%,sum≤1.0% Conforms
Loss on drying ≤1.0% 0.06%
Residue on ignition ≤0.15% 0.03%
Bacterial endotoxins ≤0.6EU/mg <0.6EU/mg

Mechanism of action

Local anesthetics block the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse, and by reducing the rate of rise of the action potential. In general, the progression of anesthesia is related to the diameter, myelination, and conduction velocity of affected nerve fibers. Clinically, the order of loss of nerve function is as follows: pain, temperature, touch, proprioception, and skeletal muscle tone.

 

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