Local Anesthetic Anesthetic Anodyne CAS 136-47-0 Tetracaine HCl / Tetracaine Hydrochloride

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: 136-47-0
Minimum Order Quantity: Negotiation
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Packaging Details: Stealth And Discreet Packaging
Delivery Time: Within 7 Working Days
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Supply Ability: 100 KG/Month
Product Name: Tetracaine Hydrochloride Other Name: Tetracaine HCl
CAS: 136-47-0 Appearance: White Powder
Usage: Pain Killer Shipping Method: EMS, HKEMS, FEDEX, DHL, UPS, Aramex, ETC
High Light:

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Local Anesthetic Anesthetic Anodyne CAS 136-47-0 Tetracaine HCl / Tetracaine Hydrochloride

 

 

Tetracaine Hydrochloride

 

Local Anesthetic Anesthetic Anodyne CAS 136-47-0 Tetracaine HCl / Tetracaine Hydrochloride 0
 

CAS:136-47-0

MF:C15H25ClN2O2

MW:300.82

EINECS:205-248-5

Synonyms:L AND OCAIN HYDROCHLORIDE;INTERCAIN HYDROCHLORIDE;MEETHOBALM HYDROCHLORIDE;2-(DIMETHYLAMINO)ETHYL 4-(N-BUTYLAMINO)BENZOATE HYDROCHLORIDE;2-DIMETHYLAMINOETHYL ESTER OFP-BUTYLAMINOBENZOIC ACID HYDROCHLORIDE;4-(N-BUTYLAMINO)BENZOIC ACID 2-(DIMETHYLAMINO)ETHYL ESTER HYDROCHLORIDE;4-[BUTYLAMINO]BENZOIC ACID-2-[DIMETHYLAMINO]ETHYL ESTER HYDROCHLORIDE;4-BUTYLAMINOBENZOIC ACID DIMETHYLAMINOETHYL ESTER HCL

 
 
Properties
 

Melting point:149°C

storage temp. Refrigerator

solubility alcohol: solublesoluble 40 parts of solvent

pka8.39(at 25℃)

Water Solubility Soluble in water at 50mg/ml

Merck 14,9188

InChIKeyPPWHTZKZQNXVAE-UHFFFAOYSA-N

 
 
Safety Information
 

Symbol(GHS)

Local Anesthetic Anesthetic Anodyne CAS 136-47-0 Tetracaine HCl / Tetracaine Hydrochloride 1Local Anesthetic Anesthetic Anodyne CAS 136-47-0 Tetracaine HCl / Tetracaine Hydrochloride 2Local Anesthetic Anesthetic Anodyne CAS 136-47-0 Tetracaine HCl / Tetracaine Hydrochloride 3

 

Description

 

Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.

 

 

Specification
 
Test Items Specification Test Results
Appearance Fine, white, crystalline, odorless powder confirm
Identification ABC in Pass confirm
Solubility Very soluble in water, soluble in Alcohol; insoluble in Ether and Benzene confirm
USP Reference standards USP Tetracaine Hydrochloride RS. USP Endotoxin RS. confirm
Melting point 145~150 degree 146.0~147.5
degree
Chromatographic purity In Pass confirm
Related substance Not more than the reference solution 0.05% confirm
Heavy metals ≤10ppm confirm
PH 4.5-6.5 5.8
Residue on ignition ≤0.10% 0.05%
Loss on Drying ≤ 0.5% 0.19%
Assay 98.0 -101.0% 100.1%
Conclusion Confirms USP 32

 

 

Usage


Tetracaine hydrochloride is a calcium channel protein inhibitor and blocks voltage-sensitive release of Ca2+ from sarcoplasmic reticulum and Tetracaine hydrochloride is used for spinal anesthesia.
 

 

 

Related products

 

Item product name CASNO.
1 Procaine HCl 51-05-8
2 Lidocaine Hydrochloride 73-78-9
3 Lidocaine 137-58-6
4 Tetracaine HCl 136-47-0
5 Benzocaine Hydrochloride 23239-88-5
6 Benzocaine 94-09-7
7 Aarticaine HCl 23964-57-0
8 Prilocaine 721-50-6
9 Prilocaine HCl 1786-81-8
10 Levobupivacaine HCl 27262-48-2
11 Ropivacaine HCl 132112-35-7
12 Ropivacaine Mesylate 854056-07-8
13 Dyclonine HCl 536-43-6
14 Mepivacaine HCl 1722-62-9
15 Chloroprocaine HCl 3858-89-7
16 Etidocaine 36637-18-0
17 Tetracaine 94-24-6

 

 

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