Nice Thymosin alpha 1 / Thymosin alpha 1 Acetate Peptide For Enhancement of Cell-Mediated Immunity

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: 62304-98-7
Minimum Order Quantity: 10 Vials
Price: Contact Us
Packaging Details: Stealth And Discreet Packaging
Delivery Time: Within 7 Working Days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 10000 Vials/Month
Other Name: Thymosin Alpha 1 MF: C129H215N33O55
MW: 3108.28 Storage Temp: -20°C
EINECS: 1592732-453-0 Packaging: In Vials
Specification: 10 Mg/vial
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Nice Thymosin alpha 1 / Thymosin alpha 1 Acetate Peptide For Enhancement of Cell-Mediated Immunity 0

 

Thymosin alpha 1

 

 

 

Basic Details:

Product Name: Thymosin alpha 1
Synonyms: Thymosin α1 Acetate;Thymosin α 1 Acetate(Thymalfasin);Thymosina1Acetate;thymosin α1 bovine;Thymosinα1 bovine,Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn;ThyMosins alpha 1;Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH acetate salt;Thymosin α1, Thymalfasin
CAS: 62304-98-7
MF: C129H215N33O55
MW: 3108.28
EINECS: 1592732-453-0
Product Categories: Amino Acid Derivatives;Peptide;Various Peptides

 

 

Abstract:

Thymosin Alpha-1 is a component of Thymosin Fraction 5 responsible for restoring immune function in animals lacking thymus glands. It was the original peptide synthesized from the Thymosin Fraction 5. Unlike β Thymosins, which are genetically and chemically unrelated, Thymosin α 1 is produced as a 28-amino acid peptide fragment from a longer, 113-amino acid precursor, prothymosin alpha. Research has shown it to enhance cell-mediated immunity in experimental animals and research subjects.

 

Thymosin Alpha-1 is being researched for the treatment of Hepatitis B and C, and it is also approved for inclusion with vaccines to boost the immune response in the treatment of other diseases.


Exhibiting a variety of immune regulating properties, thymosin-alpha-1 induces differentiation of murine T-cell precursors and human thymocytes and the terminal differentiation of functionally immature cord blood lymphocytes and induces production of IL-2, high affinity IL-2 receptors, and B-cell growth factors by peripheral blood mononuclear cells. T-helper and cytotoxic/suppressor T-cell populations are targets of thymosin activity. Thymosin-alpha-1 has been shown to increase the efficiency of antigen presentation by macrophages and to be an endogenous modulator of alpha-thrombin activity.

 


Application:

Thymosin alpha-1 is now approved in developed or developing countries for the treatment of hepatitis B and C, and is also used to enhance the immune response in the treatment of other diseases.

 

Demonstrating various immunomodulatory properties, thymosin-alpha-1-induced murine T cell precursors and human thymocyte differentiation and functional immature umbilical cord blood lymphocyte terminal differentiation and induction of IL-2, high affinity IL-2 Receptor production, and peripheral blood mononuclear cells B cell growth factor. T helper cells and cytotoxicity / inhibition of T cell populations are targets of thymosin activity.

 

It has been shown that thymosin-alpha-1 increases the efficiency of macrophage antigen presentation and is an endogenous modulator of alpha-thrombin activity.

 

 

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