Nootropic Raw Materials Powder Sunifiram / Piperazine, 1-benzoyl-4-(1-oxopropyl)- Pharmaceutical Chemical

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: 314728-85-3
Minimum Order Quantity: Negotiation
Price: Contact Us
Packaging Details: Stealth And Discreet Packaging
Delivery Time: Within 7 Work Days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 100 KG/Month
Product Name: Sunifiram Catagory: Nootropic Raw Powder
Appearance: White Powder CAS No.: 314728-85-3
Purity: 99% Min Shipping Method: EMS, HKEMS, FEDEX, DHL, UPS, Aramex, ETC
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Nootropic Raw Materials Powder Sunifiram / Piperazine, 1-benzoyl-4-(1-oxopropyl)- Pharmaceutical Chemical

 

 

Piperazine, 1-benzoyl-4-(1-oxopropyl)-

 

Nootropic Raw Materials Powder Sunifiram / Piperazine, 1-benzoyl-4-(1-oxopropyl)- Pharmaceutical Chemical 0
 

CAS: 314728-85-3

MF: C14H18N2O2

MW: 246.30492

Synonyms: Piperazine, 1-benzoyl-4-(1-oxopropyl)-;SunifiraM;1-(4-Benzoyl-1-piperazinyl)-1-propanone;1-Benzoyl-4-(1-oxopropyl)-piperazine;1-(4-Benzoylpiperazin-1-yl)propan-1-one;1-Benzoyl-4-propanoylpiperazine;Sunifiram DM235

 
 
Properties
 

Density 1.154±0.06 g/cm3 (20 ºC 760 Torr)

solubility H2O: soluble24mg/mL

color white

 

 

Abstract

 

This compound is known as an AMPAkine due to exerting most of its actions via the AMPA receptor (one of the three main subsets of glutamate receptors, alongside NDMA and kainate). This enhancement of AMPA function seems to also rely on enhancing signalling via the Glycine binding site of NMDA receptors, although one minimal signalling goes through the NMDA receptor then the benefits on AMPA receptors seem dose-dependent.

Sunifiram (DM-235) is a piperazine derived ampakine drug which acts as a positive allosteric modulator of AMPA receptors, and has nootropic effects in animal studies with significantly higher potency than piracetam. A number of related compounds are known, the best known being unifiram (DM-232).


Sunifiram operates by activating AMPA receptors; that is, the receptors that are responsible for the mediation of synaptic transmission in the central nervous system. Its mechanics also increases phosphorylation of AMPAR and NMDAR through protein kinase activation, which in turn enhances long-term potentiation - that is, an enhancement in signal transmission between two neurons resulting from simultaneous stimulation.


The kinase activation that is influenced by Sunifiram also improves cognitive defects. Additionally, Sunifiram works in the cerebral cortex of animal test subjects by assisting in the release of acetylcholine, the organic molecule that acts as a neurotransmitter in a host of various organisms. These operational mechanisms enable Sunifiram to exert anti-amnesiac properties.

 

 

COA

 

Product name Sunifiram
CAS No. 314728-85-3 Outer Packing 25KG
Production date 2017.03.18 Shelf life 2019.03.17
Standard adopted in-house specification
Items of analysis Specification Results
Appearance White to off-white crystall powder White crystall powder
Loss on drying ≤1.0% 0.20%
Mp 93~97ºC 94.5~95.5ºC
Purity >=99.5% 99.68%
Total impurity ≤0.5% 0.32%
Max Single impurity ≤0.1% 0.08%max
Conclusion Qualified

 

 

Sunifiram, also known as 1-benzoyl-4-propanoylpiperazine is a nootropic that was only first researched in the year 2000.

 

It has a similar chemical structure to Piracetam but initial studies show that it is significantly more potent than this widely used racetam.

 

Sunifiram so far shows very positive results as memory enhancer and it is currently being investigated for potential treatment of Alzheimer's and other diseases related to cognitive decline.

 

User reviews and Sunifiram logs point to the fact that this supplement makes information recall much easier and helps you think more clearly. Sunifiram is being compared to Noopept quite a bit because of their similar potency levels.

 

Initial observations suggest that Sunifiram is better as a memory booster while Noopept might have an edge on increasing focus and alertness.

 

 

How to Use


- Sunifiram is extremely potent, so small doses should be taken. It has been said that it works best when taken sublingually. This means that users place it under their tongue for administration. This will generally be a little scoop of powder. Some users have experienced a slight tingling, as you would with a breath mint. Ingestion has been reported as easy.


- Start with the smallest dose, seeing how you feel. Most users report feeling the effects within an hour of administration. You can always increase your dosage after a week or so. Since dosing is still being studied, do not exceed 10 mg. Use it sparingly or choose to cycle your doses. This means that you will cycle 'on' and 'off.' ---Spreading out your doses over the course of the week, and then taking a break.


- When purchasing online, you may notice that Sunifiram costs slightly more than other nootropics. Keep in mind that the dosage is much smaller than other nootropics. You only need a little to achieve big results. This is due to the potency offered.

 

 

Function


Sunifiram activates AMPA-mediated neurotransmission.


Enhancing LTP in a bell-shaped dose-response relationship.


Sunifiram aids in the release of acetylcholine in the cerebral cortex.


Sunifiram increases energy levels, allowing users to feel more motivated and eliminate


Sunifiram increase Levels of concentration increase, and users feel less distracted by external stimuli.


Sunifiram also enhances long-term potentiation, which is the forming of new connections regarding memory storage.


Sunifiram has some anxiolytic benefits. Feeling more relaxed is beneficial when trying to focus.

 


Recommended Dosage


This is a highly potent substance, so you should start with doses as small as 3 to 4 mg. The average user will take between 5 and 8 mg. If you take 10 mg or more, you will experience a stimulant effect closer to Adderall.


As mentioned, start with small doses and increase your dosage after a week or so.
 

Nootropic Raw Materials Powder Sunifiram / Piperazine, 1-benzoyl-4-(1-oxopropyl)- Pharmaceutical Chemical 1

 


Storage


-It is recommended to store metribolone at the room temperature below 30 degrees C.


-Keep the drug away from direct sunlight, heat and moisture.


-Do not let the drug at the sight and reach of children.
 

 

Our advantages

1. Rich experience.
Our company is a professional production leading factory in China in pharmaceutical area of many years, our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other country, and we have got very good feedback from our customers, we had Established long friendly relations of cooperation.

2. Great quality, purity and favourable.
Good quality is one of our secret success, welcome order the samples, MOQ just 10 grams.

3. Safe and fast delivery.
We have stock, so we can delivery quickly at the very day when receive the payment.
We have special way could ship 0.05kg to 3.5kg products a time. We offer melting powder into liquid service. And ship the liquid in special bottles.

4. Good after-sales service.
Tell the package update ASAP, and will try best solve when customer encountered various problems.
Welcome inquiry and order samples, we will show you our business ethics, quality/purity and safe/fast delivery.

 

 

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