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|Other Name:||Liviella ; Livial||MF:||C21H28O2|
|MP:||169 °C||Appearance:||White Solid|
trenbolone enanthate powder,
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Pharmaceutical Grade Steroid Hormone Powder Tibolone (Liviella ; Livial)
Product Name: Tibolone
Synonyms: Liviella ; Livial
Melting point: 169 °C
refractive index: 105 °(C=0.54, CH2Cl2/Et2O)
storage temp: 2-8°C
Appearance: White Solid
Tibolone is a synthetic hormone-type drug which is used mainly for hormone replacement therapy
in post-menopausal women; It is a synthetic steroid that has the same activity as the female sex
hormones estrogen and progesterone and the androgen testosterone; it helps restore hormonal
balance in the body.
Tibolone is utilized mainly for treatment of endometriosis comma; as well as hormone
replacement therapy in post-menopausal women; it is a synthetic steroid hormone drug comma;
which is fairly non-selective in its binding profile comma; acting as an agonist mainly at estrogen
receptors comma; with a preference for ER alpha; it has similar or greater efficacy compared to
older hormone replacement drugs comma; but shares a similar side effect profile; It has also
been investigated as a possible treatment for female sexual dysfunction.
When estrogen levels are low tissues can slowly degenerate comma; as is experienced during
menopause; In addition comma; low levels of estrogen can cause distressing symptoms such as
hot flushes comma; night sweats comma; mood swings comma; reduced sex drive and vaginal
dryness; Tibolone is broken down into three compounds which act in a similar way to the natural
estrogen and progesterone found in the body; It restores plasma endorphin level in post-
menopausal women and acts centrally to affect the thermo-regulatory system.
In itself Livial has no biological activity; the effects are produced mainly by the results of the
activity of its metabolites on various tissues. After administration, it is quickly metabolized into
3α-hydroxy Livial and 3ß-hydroxy Livial compounds, which are also present in an inactive,
sulfated form. A third compound, the Δ4- isomer is formed from Tibolon directly or from the 3ß
Livial has estrogenic effects on bone and vaginal tissue. The Δ4-isomer functions as a
progestogen in endometrial tissue, whereas in the brain and liver it has androgenic effects.In
breast tissue, Livial acts by strongly inhibiting sulfate activity and weak inhibition of 17α-
hydroxysteroid dehydrogenase activity, which results in blocking the conversion of estrone sulfate
Livial Contraindications;Livial is contraindicated in patients with the following conditions:,Women
with hormone treated tumors,Undiagnosed vaginal bleeding,Pregnancy/lactation,Liver and/or
cardiac disease,Livial Adverse Drug Effects,Depression,Diarrhea, constipation, nausea,
vomiting or abdominal pain,Visual disturbances,Alteration in results of liver function
tests,Excessive fluid retention in the body tissues resulting in swelling (edema),weight changes,
vaginal bleeding, pain in the muscles and joints, rashes or itching,Seborrhoeic
dermatitis,Headaches, dizziness, growth of facial hair.
How to Use:
Follow carefully instructions of use of Livial provided from your doctor. Consult your doctor or
pharmacist when in doubt. Follow the instructions of the physician in preference to those given in
this website, which may be different. Ask your doctor to explain any aspect that you do not
understand, contained in the instruction leaflet that comes with the medicine.
Livial should not be taken until two months after the last natural menstruation. If taken before, may
be increased the possibility of having an irregular vaginal bleeding.
Taking Livial for the first time
- If you have not taken any other drug for hormone replacement therapy before, you can start
If you switch from another preparation for hormone replacement therapy:
There are several types of medicines such as tablets, patches, or gels. With some of them, you
may have bleeding between cycles (sequential) and others are taken continuously.If you were
taking a sequential medicine, you should start taking Livial immediately after the end of bleeding.
If you were taking a continuous medicine (no bleeding) you may also start taking it at any time.
Livial should be taken orally. Take one tablet every day, which can be swallowed with some water
or other drink.
Take the tablets at the same time each day. The blisters (containing each one a tablet) are
marked with the corresponding day of the week.Start by taking the tablet marked with the
correspondent day of the week. For example, if it's Monday, take the tablet marked Monday on
the upper row of the blister. Follow the arrows until the blisters are empty. Start the next strip the
next day. Do not leave any day between blisters or boxes.
Relief of menopausal symptoms generally occurs during the first weeks of treatment, and optimal
results are obtained if the treatment continues for at least 3 months.If you think the effect of the
medicine is too strong or too weak, consult your doctor.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
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