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Pregabalin / Lyrica Pharmaceutical Raw Materials , Active Pharmaceutical Ingredients

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Pregabalin / Lyrica Pharmaceutical Raw Materials , Active Pharmaceutical Ingredients

Pregabalin / Lyrica Pharmaceutical Raw Materials , Active Pharmaceutical Ingredients
Pregabalin / Lyrica Pharmaceutical Raw Materials , Active Pharmaceutical Ingredients

Large Image :  Pregabalin / Lyrica Pharmaceutical Raw Materials , Active Pharmaceutical Ingredients

Product Details:
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: CAS: 148553-50-8
Payment & Shipping Terms:
Minimum Order Quantity: 10g
Price: Contact Us
Packaging Details: Stealth And Discreet Packaging
Delivery Time: Within 7 Working Days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 2000 KG/Month
Detailed Product Description
Product Name: Pregabalin Synonyms: Lyrica
MF: C8H17NO2 MW: 159.23
EINECS: 200-659-6 Melting Point: 194-196°C
Appearance: Off-White Solid
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99.8% High Quality Pregabalin / Lyrica Powder With Safe Delivery & Favorable Price



Pregabalin is described chemically as (S)-3-(aminomethyl)-5-methylhexanoic acid. The


molecular formula is C8H17NO2 and the molecular weight is 159.23. Pregabalin is a white to off-


white, crystalline solid with a pKa1 of 4.2 and a pKa2 of 10.6. It is freely soluble in water and both


basic and acidic aqueous solutions. The log of the partition coefficient (n-octanol/0.05M


phosphate buffer) at pH 7.4 is 1.35.


LYRICA (pregabalin) Capsules are administered orally and are supplied as imprinted hard-shell


capsules containing 25, 50, 75, 100, 150, 200, 225, and 300 mg of pregabalin, along with


lactose monohydrate, cornstarch, and talc as inactive ingredients. The capsule shells contain


gelatin and titanium dioxide. In addition, the orange capsule shells contain red iron oxide and the


white capsule shells contain sodium lauryl sulfate and colloidal silicon dioxide. Colloidal silicon


dioxide is a manufacturing aid that may or may not be present in the capsule shells. The


imprinting ink contains shellac, black iron oxide, propylene glycol, and potassium hydroxide.

LYRICA (pregabalin) oral solution, 20 mg/mL, is administered orally and is supplied as a clear,


colorless solution contained in a 16 fluid ounce white HDPE bottle with a polyethylene-lined


closure. The oral solution contains 20 mg/mL of pregabalin, along with methylparaben,


propylparaben, monobasic sodium phosphate anhydrous, dibasic sodium phosphate anhydrous,


sucralose, artificial strawberry #11545 and purified water as inactive ingredients.




Pregabalin belongs to a group of medicines known as anti-epileptic medicines, although it is


prescribed for the treatment of several different conditions. You may have been prescribed it for


the treatment of partial seizures, which is a type of epilepsy. A seizure is a short episode of


symptoms which is caused by a burst of abnormal electrical activity in the brain. With a partial


seizure, the burst of electrical activity stays in one part of the brain. Therefore, you tend to have


localised or 'focal' symptoms. Pregabalin is also prescribed to treat certain types of long-lasting


pain caused by damage to nerves. This type of pain, called neuropathic pain, can be caused by a


number of different conditions, including diabetes (where it is called diabetic neuropathy) and


shingles(where it is called postherpetic neuralgia).



Medical uses:


1. Seizures

Pregabalin is useful when added to other treatments, when those other treatments are not


controlling partial epilepsy. Its use alone is less effective than some other seizure medications.


It is unclear how it compares to gabapentin for this use.



2. Neuropathic pain

The European Federation of Neurological Societies recommends pregabalin as a first line agent


for the treatment of pain associated with diabetic neuropathy, post-herpetic neuralgia, and central


neuropathic pain. A minority obtain substantial benefit, and a larger number obtain moderate


benefit. Other first line agents, including gabapentin and tricyclic antidepressants, are given equal


weight as first line agents, and unlike pregabalin, are available as less expensive generics.



Pregabalin is not recommended for certain other types of neuropathic pain such as pain that of


trigeminal neuralgia or HIV infection and its use in cancer-associated neuropathic pain is


controversial. There is no evidence for its use in the prevention of migraines and gabapentin has


been found not to be useful. It has been examined for the prevention of post-surgical chronic pain,


but its utility for this purpose is controversial.



3. Anxiety disorders



Lab Test Result:


Test Items








A white to off white powder


White powder





A. Meets the requirement




B. IR: similar to Reference Substance




Loss on drying






Specific Rotation







Related Substances


Any single impurity ≤0.1%

Total impurity ≤0.8%





Purity By HPLC R-isomer






Residue on ignition







Residual solvents


Isopropyl alcohol ≤5000ppm

Ethyl Acetate ≤5000ppm





Heavy metals




















It conforms with EP standard



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