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Raw Materials For Pharmaceutical Industry , Strong Pain Relieving / Fever Reducing Drugs

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Raw Materials For Pharmaceutical Industry , Strong Pain Relieving / Fever Reducing Drugs

Raw Materials For Pharmaceutical Industry , Strong Pain Relieving / Fever Reducing Drugs
Raw Materials For Pharmaceutical Industry , Strong Pain Relieving / Fever Reducing Drugs

Large Image :  Raw Materials For Pharmaceutical Industry , Strong Pain Relieving / Fever Reducing Drugs

Product Details:
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: CAS: 62-44-2
Payment & Shipping Terms:
Minimum Order Quantity: 100g
Price: Contact Us
Packaging Details: Stealth And Discreet Packaging
Delivery Time: Within 7 Working Days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 3000 KG/Month
Detailed Product Description
Product Name: Phenacetin MF: C10H13NO2
MW: 179.22 EINECS: 200-533-0
MP: 133-136 °C BP: 132 °C
Storage Temp: 2-8°C Water Solubility: 0.076 G/100 ML
Sensitive: Hygroscopic Appearance: White Powder
High Light:

pharmaceutical active ingredients

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Strong Pain-relieving & Fever-reducing Drug Raw Powder Phenacetin Powder

 


Description:

 

It is also called acetophenetidin. Having glossy leaflets or scales-like crystals that have no odor or

 

taste. Melting point 133-136 °C. Stable in air, soluble in water, slightly soluble in boiling water,

 

slightly soluble in ether, soluble in ethanol, chloroform. It is formed through the

 

etherification,reduction and Acetylation reaction of pchloronitrobenzene. As chloroacetanilide

 

antipyretic and analgesic agent. Suitable for fever,headache, neuralgia and other drugs as a

 

compound agent.
 

 

Antipyretic effect is stronger than the analgesic effect. Effect of strength is slow and long-lasting

 

as aspirin, low toxicity. Research shows that: This product and its metabolites acetaminophen

 

have the antipyretic effect. Because the enzyme inhibitor make phenacetin not be converted into

 

paracetamol, still showed obvious antipyretic effect,thus the antipyretic effect after the product

 

line not converrt to paracetamol.The mild phenacetin analgesic effect usually lasts 3 to 4 hours;

 

and synergistic effect, of alicylic acid coadministrationmake the analgesic effect enhancement.

 

The main clinical is for small animal antipyretic analgesic. This product is also a component of the

 

APC tablet.
 

 

Phenacetin is a pain-relieving and fever-reducing drug, widely used from its introduction in 1887

 

until banned in the US by the FDA in 1983. Its use has declined because of its adverse effects,

 

which include increased risk of certain cancers and kidney damage. It is metabolized into

 

paracetamol, which replaced it in some over-the-counter medications following the ban

 

on phenacetin.

 

 

Raw Materials For Pharmaceutical Industry , Strong Pain Relieving / Fever Reducing Drugs 0

 

 

Usage:

 

Phenacetin was widely used until the third quarter of the twentieth century, often in the form of

 

aspirin-phenacetin-caffeine compound analgesic, as a remedy for fever and pain. An early

 

formulation was Vincent's APC in Australia. As a result, some branded, previously phenacetin-

 

based preparations continued to be sold, but with the phenacetin replaced by safer alternatives.

 

A popular brand of phenacetin was Roche's Saridon, which was reformulated to contain

 

propyphenazone, paracetamol and caffeine. Coricidin was also reformulated without phenacetin.

 

Paracetamol is a metabolite of phenacetin with similar analgesic and antipyretic effects, but the

 

new formulation has not been found to have phenacetin's carcinogenicity.

 

Phenacetin is now being used as a cutting agent to adulterate cocaine in the UK and Canada,

 

owing to the similar physical features of the two drugs.

 

Due to low-cost phenacetin is used for research into the physical and refractive properties of

 

crystals. It is an ideal compound for this type of research

 

 

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