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Safe Pass Raw Materials Powder PRL-8-53 / PRL-8-53 HCL CAS 51352-87-5 For Improving Brain Cycle

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Safe Pass Raw Materials Powder PRL-8-53 / PRL-8-53 HCL CAS 51352-87-5 For Improving Brain Cycle

Safe Pass Raw Materials Powder PRL-8-53 / PRL-8-53 HCL CAS 51352-87-5 For Improving Brain Cycle
Safe Pass Raw Materials Powder PRL-8-53 / PRL-8-53 HCL CAS 51352-87-5 For Improving Brain Cycle Safe Pass Raw Materials Powder PRL-8-53 / PRL-8-53 HCL CAS 51352-87-5 For Improving Brain Cycle

Large Image :  Safe Pass Raw Materials Powder PRL-8-53 / PRL-8-53 HCL CAS 51352-87-5 For Improving Brain Cycle

Product Details:
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: 51352-87-5
Payment & Shipping Terms:
Minimum Order Quantity: Negotiation
Price: Contact Us
Packaging Details: Stealth And Discreet Packaging
Delivery Time: Within 7 Work Days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 100 KG/Month
Detailed Product Description
Product Name: PRL-8-53 Synonyms: PRL-8-53 HCL
Appearance: White Powder CAS No.: 51352-87-5
Purity: 99% Min Shipping Method: EMS, HKEMS, FEDEX, DHL, UPS, Aramex, ETC
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Safe Pass Raw Materials Powder PRL-8-53 / PRL-8-53 HCL CAS 51352-87-5 For Improving Brain

 

 

PRL-8-53

 

Safe Pass Raw Materials Powder PRL-8-53 / PRL-8-53 HCL CAS 51352-87-5 For Improving Brain Cycle 0
 

CAS: 51352-87-5

MF: C18H22ClNO2

MW: 319.82578

Synonyms: PRL-8053;PRL-8-53;Methyl 3-(2-(benzyl(Methyl)aMino)ethyl)benzoate hydrochloride;3-(2-Benzyl(methyl)aminoethyl)benzoic acid methyl ester hydrochloride;m-[2-(Benzylmethylamino)ethyl]benzoic acid methyl ester hydrochloride;Benzoic acid, 3-(2-(Methyl(phenylMethyl)aMino)ethyl)-, Methyl ester, hydrochloride;Methyl 3-(2-(benzyl(methyl)

 

 

Abstract

 

PRL-8-53 (chemical name Methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate) is a synthetic nootropic compound discovered in 1972 and patented in 1975 by the late Dr. Nikolaus Hansl, a neuropharmacologist at Creighton University in Omaha, Nebraska. Preliminary animal tests indicated that the compound was both safe and significantly nootropic, boosting avoidance learning in rodents with no adverse effects. But the real interest in PRL-8-53 was sparked by a 1978 study on human volunteers, which showed that a single dose of the compound could improve word retention scores by more than 200%

 

Application

PRL-8-53's exact mechanisms of action are not well understood, but it is generally believed to regulate the brain's production of and response to several crucial neurotransmitters. In his reports on human and animal studies Hansl indicated that PRL-8-53 potentiates dopamine, partially restricts production of serotonin, and enhances the brain's response to acetylcholine.

Though Hansl's research report on the 1978 human study suggests those actions, it does not clearly delineate the mechanism of action.The fact that older subjects saw the most nootropic benefit from taking the drug supports the concept that dopamine modulation plays a major role in PLR-8-53's effects. Up-regulating the normal age-related lessening of dopamine production that is associated with cognitive decline could have a significant positive impact on both learning and memory.

 

 

Specification
 
Item  

Inspection Standard

 

Results

 

Appearance

 

Off white solid powder

 

Conform

 

Identification

 

Conform with NMR

 

Conforms

 

Melting Point

149-152°C 150-151°C
 

Loss on Drying

≤0.50%  

0.21%

Residue on ignition ≤1.0%  

0.32%

 

Purity(HPLC)

 

≥99%

 

99.2%

 

Heavy metals

 

NMT 20PPM

 

Conforms

Conclusion:This product by inspection accords with the in-house standard

 

 

Dosage

The only human study on PRL-8-53 was based on the ingestion of a single 5 mg dose. There is no data on the effectiveness or potential toxicity of any other dosage in humans.

 

 

Safe Pass Raw Materials Powder PRL-8-53 / PRL-8-53 HCL CAS 51352-87-5 For Improving Brain Cycle 1

 


Side Effect


No adverse effects from a single 5 mg dose of PRL-8-53 were observed in the human study. Animal studies suggest that the compound has a high therapeutic threshold, but evidence is very limited because no comprehensive toxicity studies have been completed.

 

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