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Strong Effect Analgesic & Antipyretic 4-Acetamidophenol ( Paracetamol ) Powder

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Strong Effect Analgesic & Antipyretic 4-Acetamidophenol ( Paracetamol ) Powder

Strong Effect Analgesic & Antipyretic 4-Acetamidophenol ( Paracetamol ) Powder
Strong Effect Analgesic & Antipyretic 4-Acetamidophenol ( Paracetamol ) Powder

Large Image :  Strong Effect Analgesic & Antipyretic 4-Acetamidophenol ( Paracetamol ) Powder

Product Details:
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: CAS: 103-90-2
Payment & Shipping Terms:
Minimum Order Quantity: 100g
Price: Contact Us
Packaging Details: Stealth And Discreet Packaging
Delivery Time: Within 7 Working Days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 3000 KG/Month
Detailed Product Description
Product Name: 4-Acetamidophenol Other Name: Paracetamol
MF: C8H9NO2 MW: 151.16
EINECS: 203-157-5 MP: 168-172 °C
FP: 11 °C Density: 1.293 G/cm3
Water Solubility: 14 G/L (20°C) Appearance: White Crystalline Solid
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Strong Effect Analgesic & Antipyretic 4-Acetamidophenol (Paracetamol) Powder

 


Description:


This product is acetanilide antipyretic analgesics. By inhibiting ring oxidase and

 

selectivity in the hypothalamus of the temperature regulating center, the synthesis of

 

prostaglandins in peripheral vascular expansion, sweating and antipyretic effect, strength of

 

its antipyretic effect similar to aspirin.

 

Paracetamol is a widely used over-the-counter analgesic (pain reliever) and antipyretic

 

(fever reducer). Acetaminophen is the name adopted for this pharmacologic agent in the U. S.

 

(USAN) and Japan; Paracetamol is approved in a variety of international venues.
 

Paracetamol is classified as a mild analgesic. It is commonly used for the relief of

 

headaches and other minor aches and pains and is a major ingredient in numerous cold and flu

 

remedies. In combination with opioid analgesics, paracetamol can also be used in the

 

management of more severe pain such as post-surgical pain and providing palliative care in

 

advanced cancer patients. Though paracetamol is used to treat inflammatory pain, it is not

 

generally classified as an NSAID because it exhibits only weak anti-inflammatory activity.

 


Application:
 

Paracetamol is approved for reducing fever in people of all ages.
 

Paracetamol is used for the relief of pains associated with many parts of the body. It has

 

analgesic properties comparable to those of aspirin, while its antiinflammatory effects are

 

weaker. It is better tolerated than aspirin in patients in whom excessive gastric acid

 

secretion or prolongation of bleeding time may be a concern.
 

Paracetamol powder nutritional supplemen Mainly used for amino acid infusion,due to special

 

wettability, also used in cold cream,osmetics. Serine constitute the human body of several

 

kinds of essential amino acid of protein a, for the construction of protein has a very

 

important role.

 

 

Research Result:

 

Since their synthesis in the late 1800s paracetamol (acetaminophen) and phenacetin have

 

followed divergent pathways with regard to their popularity as mild analgesic/antipyretic drugs.

 

Initially, paracetamol was discarded in favour of phenacetin because the latter drug was

 

supposedly less toxic. Today the opposite is true, and paracetamol, along with aspirin, has

 

become one of the two most popular 'over-the-counter' non-narcotic analgesic agents. This

 

marked increase in the wide approval attained by paracetamol has been accompanied by the

 

virtual commercial demise of phenacetin because of its role, albeit somewhat circumstantial, in

 

causing analgesic nephropathy. Both paracetamol and phenacetin are effective mild analgesics,

 

suitable for treating mild to moderate pain, and their actions are broadly comparable with those

 

of aspirin and related salicylates, although they do not appear to possess significant anti-

 

inflammatory activity. Since a major portion of a dose of phenacetin is rapidly metabolised to

 

paracetamol, it seems possible that phenacetin owes some of its therapeutic activity to its main

 

metabolite, paracetamol, whereas its most troublesome side effect (methaemoglobinaemia) is

 

due to another metabolite, p-phenetidine. The mechanism of action of paracetamol is poorly

 

defined, although it has been speculated that it may selectively inhibit prostaglandin production in

 

the central nervous system, which would account for its analgesic/antipyretic properties. The lack

 

of any significant influence on peripheral cyclooxygenase would explain the absence of anti-

 

inflammatory activity. At therapeutic doses paracetamol is well tolerated and produces fewer side

 

effects than aspirin. The most frequently reported adverse effect associated with paracetamol is

 

hepatotoxicity, which occurs after acute overdosage (usually doses greater than 10 to 15g are

 

needed) and, very rarely, during long term treatment with doses at the higher levels of the

 

therapeutic range. Paracetamol damages the liver through the formation of a highly reactive

 

metabolite which is normally inactivated by conjugation with glutathione. Overdoses of

 

paracetamol exhaust glutathione stores, thus allowing the accumulation of this toxic metabolite

 

which covalently binds with vital cell elements and can result in liver necrosis. Glutathione

 

precursors (notably intravenous N-acetylcysteine) have proved remarkably successful in treating

 

paracetamol overdose, as long as treatment is initiated within 10 hours.

 

 

Strong Effect Analgesic & Antipyretic 4-Acetamidophenol ( Paracetamol ) Powder 0

 

 

 
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