White Local Anesthetic Powder Tetracaine Hydrochloride / Tetracaine HCl

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: CAS: 94-24-6
Minimum Order Quantity: 100g
Price: Contact Us
Packaging Details: Stealth And Discreet Packaging
Delivery Time: Within 7 Working Days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 800 KG/Month
Product Name: Tetracaine MF: C15H24N2O2
MW: 264.36 EINECS: 202-316-6
Storage Temp: 2-8°C Apparence: White Powder
High Light:

local anesthesia drugs

,

pure benzocaine powder

White Local Anesthetic Powder Tetracaine Hydrochloride / Tetracaine HCl 0

 

Tetracaine HCL
 


Chemical Names: Tetracaine hydrochloride; Tetracaine HCl; Butethanol; Butylocaine; Anethain
CAS number: 136-47-0;
Molecular Formula: C15H25ClN2O2
Molecular Weight: 300.827 g/mol

Tetracaine (also known as amethocaine) is a local anesthetic of the ester anesthetic group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

Tetracaine is the T in TAC, a mixture of 5 to 12% tetracaine, 0.05% adrenaline, and 4 or 10% cocaine hydrochloride used in ear, nose, and throat surgery and in the emergency department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.



 

Pharmacodynamic properties
Tetracaine hydrochloride is used as a local anaesthetic which acts by reversibly blocking the propagation and conduction of nerve impulses along nerve axons. Tetracaine stabilises the nerve membrane, preventing the increase in sodium permeability necessary for the production of an action potential.

 

 

Pharmacokinetic properties
Tetracaine is a weak base (pKa 8.5), therefore, significant changes in the rate of ionised lipid soluble drug uptake may occur with changes in the acid base balance.
In vitro studies have shown that tetracaine has a high affinity for melanin, therefore, differences in duration of action may be expected between deeply pigmented eyes and less pigmented eyes.
The primary site of metabolism for tetracaine is the plasma. Pseudocholinesterases in the plasma hydrolyse tetracaine to 4-aminobenzoic acid. Unmetabolised drug is excreted in the urine.

 

 

Preclinical safety data
No adverse safety issues were detected during the development of this formulation. The active ingredient is well established in clinical ophthalmology.

 

 

Test Report :

Related Categories Bioactive Small Molecule Alphabetical Index,Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Ion Channels, More
Assay ≥99%
Solubility alcohol: solublesoluble 40 parts of solvent
  chloroform: solublesoluble in 30 parts of solvent
  acetone: insoluble
  benzene: insoluble
  diethyl ether: insoluble

 

 

 

Local Anesthetic Powder

 

Benzocaine Procaine Lidocaine Tetracaine
Benzocaine HCL Procaine HCL Lidocaine HCL Tetracaine HCL
Dimethocaine Prilocaine Articaine HCL Pramoxine HCL
Dimethocaine HCL Prilocaine HCL Bupivacaine HCL Proparacaine HCL

Contact Details
sales

Phone Number : +8615827096298

WhatsApp : +https://api.whatsapp.com/send?phone=8613657291547