Place of Origin: | CHINA |
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Brand Name: | TINGYI |
Certification: | GMP , ISO 9001:2008 |
Model Number: | 479-41-4 |
Minimum Order Quantity: | Negotiation |
Price: | Contact Us |
Packaging Details: | Stealth And Discreet Packaging |
Delivery Time: | Within 7 Work Days |
Payment Terms: | Bank Transfer - Bitcoin - Western Union - MoneyGram |
Supply Ability: | 100 KG/Month |
Product Name: | Indirubin | Other Name: | Folium Isatidis Extract |
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CAS: | 491-70-3 | Appearance: | Purple Pink Powder |
Catagoty: | Herbal Extract | Shipping Method: | EMS, HKEMS, FEDEX, DHL, UPS, Aramex, ETC |
High Light: | pharmaceutical active ingredients,pharmaceutical anabolic steroids |
Factory supply Best price Chinese Herbal Extract Anti-Cancer Indirubin / Folium Isatidis Extract By HPLC CAS 479-41-4
CAS:479-41-4
MF:C16H10N2O2
MW:262.26
Synonyms:[2,3'-Biindolinylidene]-2',3-dione;Indirubin (Synthetic), >=98%;Indirubin/Folium Isatidis Extract;Isoindogotin;(delta(sup2,3’)-biindoline)-2’,3-dione ;3-(1,3-dihydro-3-oxo-2h-indol-2-ylidene)-1,3-dihydro-2h-indol-2-on ;c.i.73200 ;2-(2-oxo-1h-indol-3-ylidene)-1h-indol-3-one
Abstract
Indirubin is an active ingredient of anti-leukemia isolated from dried leaves of Isatis indigotica Fort. For the treatment of chronic myeloid leukemia, the total effective rate was 87.3%. In terms of reducing white blood cells effect, Indirubin is similar to Maryland, but better than Maryland in reducing liver. Its' blood and bone marrow mitigation effect is worse than Maryland, and has no cross tolenrance with Maryland.
Indirubin also has a certain effect on acute myeloid leukemia. It can be used for abnormal myelopathy and eosinophilia. Indirubin has inhibiting effect on a variety of transplanted animal tumors, and can destroy leukemia cells. With the effect of Indirubin, cells of degeneration and necrosis show swelling and soluble necrosis. Through experimental studies it is found that Indirubin can enhance the animal's monocyte-macrophage system's phagocytosis. Indirubin has no direct effect on protein synthesis. Its' inhibition of DNA synthesis is due to inhibition of DNA polymerase, affecting the polymerization of DNA. Indirubin metabolizes in liver and gallbladder after intravenous injection or intragastric administration. After 96 hours 76.03% Indirubin was eliminated by faeces. After taking this product, the mice's blood concentration gradually increased, after 12 hours it reached the peak, slowed down after a month, maintaining a long time. Indirubin is highly distributed in liver, gallbladder and gastrointestinal. Bioavailability was 46.48%.
Indication
Indirubin has anti-cancer effect. It is clinically used for the treatment of chronic myeloid leukemia.
Usage and Dosage
Adult Dosage: 50 ~ 300mg/day, generally 200mg/day, 3 to 4 times/day by taking orally until symptoms relieved or 3 months for a course of treatment.
Dosage From
Indirubin Tablet: 25mg; 50mg; 100mg.
Herbal Extractions | ||
TUDCA | CAS 14605-22-2 | In-house Standard |
Ursodeoxycholic Acid | CAS 128-13-2 | In-house Standard |
Triacetyluridine | CAS 4105-38-8 | In-house Standard |
Yohimbine hydrochloride | CAS 65-19-0 | 98% +HPLC |
Rauwolscine hydrochloride | CAS 6211-32-1 | 98% +HPLC |
Forskolin | CAS 66428-89-5 | 98% +HPLC |
5-Alpha-Hydroxy-Laxogenin | CAS 56786-63-1 | 98% +HPLC |
Cycloastragenol | CAS 84605-18-5 | 50% 98% |
Taxifolin | CAS 480-18-2 | 98% +HPLC |
Phosphatidylserine | CAS 51446-62-9 | 20% 50% |
Tomatidine | CAS 77-59-8 | 98% +HPLC |
Vinpocetine | CAS 42971-09-5 | 98%+ HPLC |
Vincamine | CAS 1617-90-9 | 98%+ HPLC |
Resveratrol | CAS 501-36-0 | 98%+ HPLC |
Huperzine A | CAS 120786-18-7 | 1% 95% 98% |
Epicatechin | CAS 490-46-0 | 90% 95% 98% |
ECG | CAS 1257-08-5 | 98% +HPLC |
Epigallocatechin EGC | CAS 970-74-1 | 98% +HPLC |
Tetrahydropalmatine | CAS 10097-84-4 | 98% +HPLC |
Wogonin | CAS 632-85-9 | 98% +HPLC |
Tangeretin | CAS 481-53-8 | 98% +HPLC |
Orientin | CAS 28608-75-5 | 98% +HPLC |
Osthol | CAS 484-12-8 | 98% +HPLC |
Loganin | CAS 18524-94-2 | 98% +HPLC |
Luteolin | CAS 491-70-3 | 50% 98% |
CAS 479-41-4 | 98% +HPLC | |
Galantamine Hydrobromide | CAS 1953-04-4 | 98% +HPLC |
Fisetin | CAS 528-48-3 | 50% |
Diosgenin | CAS 512-04-9 | 98% +HPLC |
Cytisine | CAS 485-35-8 | 98% +HPLC |
Celastrol | CAS 34157-83-0 | 98% +HPLC |
Hydroxytyrosol | CAS 10597-60-1 | 98% +HPLC |
Bufalin | CAS 465-21-4 | 98% +HPLC |
Baicalein | CAS 491-67-8 | 98% +HPLC |
Astilbin | CAS 29838-67-3 | 80% |
Artemisinin | CAS 63968-64-9 | 98% +HPLC |
beta-Carotene | CAS 7235-40-7 | 96%+ HPLC |
Synephrine HCL | CAS 5985-28-4 | 98% +HPLC |
Higenamine | CAS 5843-65-2 | In-house Standard |
CAS 770-05-8 | 98% +HPLC | |
5-HTP | CAS 314062-44-7 | 98%+ HPLC |