Cough Reliever Drugs Dxm 6700-34-1/125-69-9 Dextromethorphan Hydrobromide

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: CAS: 6700-34-1
Minimum Order Quantity: 10g
Price: Contact Us
Packaging Details: Stealth And Discreet Packaging
Delivery Time: Usually within 7 work days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 500 KG/Month
Product Name: Dextromethorphan Hydrobromide Synonyms: DXM
MF: C18H28BrNO2 MW: 370.32
Appearance: White Solid Function: Antitussive
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Tag:Dextromethorphan HydrobromideWeight Loss Powders;Dextromethorphan Maleate HBR;
Antitussive Drug

Basic Description:
Product Name Dextromethorphan Hydrobromide
Synonyms Dextromethorphan maleate HBR; dextromethorphan HBR;
(9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan hydrobromide; 3-methoxy-17-methylmorphinan hydrobromide;
(9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan hydrobromide hydrate;
Destromethorphan hydrobromide
Molecular Formula C18H28BrNO2
Molecular Weight 370.3244
InChI InChI=1/C18H25NO.BrH.H2O/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H;1H2/t15-,17+,18+;;/m1../s1
CAS Registry Number 125-69-9
EINECS 204-750-1
Molecular Structure  
Boiling point 486.1°C at 760 mmHg
Flash point 247.8°C
Vapour Pressure 2.92E-10mmHg at 25°C
Assay 99%
Appearance White or white crystalline powder


Description:

Dextromethorphan (DXM or DM) is an antitussive (cough suppressant) drug. It is one of the active
ingredients in many over-the-counter cold and cough medicines, including generic labels
and store brands, Benylin DM, Mucinex DM, Robitussin, NyQuil, Dimetapp, Vicks, Coricidin,
Delsym, TheraFlu, and others. Dextromethorphan has also found other uses in medicine, ranging
from pain relief to psychological applications. It is sold in syrup, tablet, spray, and lozenge forms.
In its pure form, dextromethorphan occurs as a white powder.

Medical use

Generic Dextromethorphan syrup.
The primary use of dextromethorphan is as a cough suppressant, for the temporary relief of cough
caused by minor throat and bronchial irritation (such as commonly accompanies the flu and
common cold), as well as those resulting from inhaled particle irritants.

A 2004 study showed that dextromethorphan was no more effective for children than a placebo.
Studies conducted by the American Academy of Pediatrics show that dextromethorphan is not
superior to a placebo in providing nocturnal symptom relief for children with cough and sleep
difficulty due to upper respiratory infections.

A combination of dextromethorphan and quinidine, a CYP2D6 inhibitor, has been shown to alleviate
symptoms of easy laughing and crying (pseudobulbar affect) in patients with amyotrophic lateral
sclerosis and multiple sclerosis.Dextromethorphan is also being investigated as a possible treatment
for neuropathic pain and pain associated with fibromyalgia.In 2010, the FDA approved the
combination product dextromethorphan/quinidine (Nuedexta) for the treatment of pseudobulbar
affect (PBA).

Dextromethorphan has been shown to be effective in treating opioid withdrawal. At doses of 2 mg/kg
in rats all signs of opioid withdrawal were eliminated.


COA:
TEST SPECIFICATION TEST RESULT
Apperance Practically white crystal or
crystalline powder
White crystalline powder
Identification A. FT-IR The sample spectrum correspond to
that of the reference standard
Conforms
B. UV Not more than 3.0% difference
of RS(on anhydrous basis)
1.4%
C. Bromide Test Yellow white precipitate formed Conforms
Specific rotation A 1.8w/v in water:Not more than 1.0%
difference of RS
At 325nm and 25ºC(on anhydrous basis)
0.23%
Specific rotation B 2.0%w/v in 0.1M HCL: +28ºCto +30ºC
at 589nm and 20ºC(on anhydrous basis)
+28.2ºC
Clarity of solution 5.0%w/v in alcohol:Clear and colorless Conforms
PH 5.2-6.5(1 in 100 water solution) 6.1
Acidity or Alkalinity Not more than 0.4ml of
0.01M HCLconsumed
0.24ml
Water(by KF Titration) 4.0%-5.5% 5.0%
Relates substances
(by HPLC;ph;Eur)
a)For each of impurities A,B,C,D
not more than 0.5%
Impurities A,B,C,D;
Not detected.
b)Among impurities A,B,C,D not
more than one greater than 0.25%
0
C)For each of unspecified impurities,
not more than0.10%
<0.05%
d)Total impurities not more than 1.0% <0.05%
Residue on Ignition Not more than 1.0% 0.05%
N,N-Dimethylaniline Not more than 0.001% Conforms
Phenolic compounds No blue-green color develops Conforms
Assay A (by HPLC) 98.0%~102.0%(on anhydrous basis) 100.0%
Assay B(by titration) 99.0%~101.0%(on anhydrous basis) 100.4%
Residual solvents Methanol≤3000ppm

Toluene≤890ppm

Acetone≤5000ppm
52ppm

0.8ppm

2ppm
Storage Preserve in tight containers;
protected from light
Conforms
Compliance Statement USP35/EP7

Our advantage:

1.Good quality.All products are produced under GMP conditions according to Standard Operation 1.Procedure(SOP), not from little underground labs or black markets, so the quality is guaranteed.

2.Discreet packing methods.For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels.

3.99.99% customs clearance rate. We have rich experience in shipping parcel to USA, Australia, UK, Canada, Brazil, Russia, Germany, Poland, Mexico, etc.

4. Injectable steroid. We offer melting powder into liquid service. And ship the liquid in special bottles .1. Good quality.All products are produced under GMP conditions according to Standard Operation Procedure(SOP), not from little underground labs or black markets, so the quality is guaranteed.

5. Discreet packing methods. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels.

6. Injectable steroid. We offer melting powder into liquid service. And ship the liquid in special bottles.

Contact Details
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