Chemicals Raw Powder Pharmaceutical Raw Materials Oxiracetam Nootropic CAS 62613-82-5

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: 62613-82-5
Minimum Order Quantity: 10g
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Supply Ability: 100 KG/Month
Product Name: Oxiracetam Synonyms: Hydroxypiracetam
CAS: 62613-82-5 Appearance: White Powder
Usage: Cognitive Enhancer Shipping Method: EMS, HKEMS, FEDEX, DHL, UPS, Aramex, ETC
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Pharmaceutical Chemicals Raw Powder Oxiracetam Nootropic CAS 62613-82-5

 

Oxiracetam

 

Chemicals Raw Powder Pharmaceutical Raw Materials Oxiracetam Nootropic CAS 62613-82-5 0
 
Description:

Oxiracetam is one of the three first-tier racetam compounds, being produced after both Piracetam and Aniracetam. Oxiracetam appears to enhance the release of excitatory neurotransmitters and can aid in memory formation, but lacks human studies.

All Essential Benefits/Effects/Facts & Information

Oxiracetam is one of the racetams, and is structurally different from piracetam due to a single hydroxyl group. It is also used for nootropic purposes such as enhancing learning in students or preventing against cognitive decline. Like all other racetams, it is a synthetic molecule that is not found in food sources or in nature.

When looking at the evidence for oxiracetam at this point in time it seems to have a fair bit of human evidence for reducing the rate of organic cognitive decline (a natural loss in cognition that occurs during the aging process that is not associated with any disease state) and with dementia, yet the lone study in persons with Alzheimer's showed no apparent benefit with oxiracetam supplementation. When it does aid in cognitive decline, it is somewhat comparable in potency to Alpha-GPC and seems to be slightly more potent than piracetam.

There is currently no evidence to support cognitive enhancement of oxiracetam in young humans with no cognitive impairment looking to increase memory formation.

When looking at animal evidence, oxiracetam appears to very reliably and potently prevent amnesia induced by a variety of anti-cholinergic or anti-glutaminergic compounds (injections of 3-30mg/kg in rats pretty much normalizing memory formation). It has been implicated in increasing memory formation in otherwise healthy and young rats/mice with no apparent cognitive impairment (suggesting that it can be used as a nootropic) but it appears to require at least a five day loading period.

Oxiracetam is a positive AMPA modulator similar in mechanism and potency (but not binding site) to both piracetam and aniracetam but may have an additional benefit of increasing glutamate, acetylcholine, and D-aspartic acid release from activated but not resting neurons. This two-fold sequence (enhancing glutamate release and then positively modulating one of the receptors it signals through) ultimately increases metabolic activity in neuronal cells and memory formation.
 
Specification
 
Oxiracetam /4-Hydroxy-2-oxopyrrolidine-N-acetamide Basic information
Product Name: 4-Hydroxy-2-oxopyrrolidine-N-acetamide
Synonyms: 4-HYDROXY-2-OXOPYRROLIDINE-N-ACETAMIDE;4-hydroxy-2-oxo-1-pyrrolidineacetamid;4-hydroxy-2-oxo-1-pyrrolidineacetamide;4-hydroxypiracetam;ct-848;hydroxypiracetam;isf2522;OXIRACETAM
CAS: 62613-82-5
MF: C6H10N2O3
MW: 158.16
EINECS:  
Product Categories: Pharmaceutical material and intermeidates;APIs;API;(intermediate of oxiracetam);Amines;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Brain health drug;Nootropic
Mol File: 62613-82-5.mol
 
 
4-Hydroxy-2-oxopyrrolidine-N-acetamide Chemical Properties
mp 165-168 °C
density 1.416
storage temp. 2-8°C
CAS DataBase Reference 62613-82-5(CAS DataBase Reference)
 
Safety Information
Hazard Codes Xi
Risk Statements 36/38
Safety Statements 26-36
WGK Germany 3
RTECS UX9656638
 
MSDS Information
ProviderLanguage
4-Hydroxy-2-oxopyrrolidine-N-acetamide English
SigmaAldrich English
 
4-Hydroxy-2-oxopyrrolidine-N-acetamide Usage And Synthesis
Chemical Properties Whie Solid
Usage Nootropic. Analog of Piracetam with psychostimulant activity.
 
4-Hydroxy-2-oxopyrrolidine-N-acetamide Preparation Products And Raw materials
Raw materials Etanol-->Dichloromethane-->Ethyl 2-bromopropionate-->Silica glass-->1,1-Dimethoxyethane-->ETHYL PYRROLIDINOACETATE

Effect

1 Memory and Learning

2 Glutaminergic Neurotransmission

3 Cholinergic Neurotransmission

4 Attention and Arousal

5 Sleep and Sedation

6 Catecholamines

7 Dopaminergic Neurotransmission

8 GABAergic Neurotransmission

9 Serotonergic Neurotransmission

10 Neuroprotection

11 Bioenergetics
 
 
Nootropics
NO Product Name purity CAS
1 Sunifiram 99% 314728-85-3
2 Coluracetam 99% 135463-81-9
3 PRL-8-53 99% 51352-87-5
4 NSI-189 99% 1270138-40-3
5 Fasoracetam 99% 110958-19-5
6 IDRA-21 99% 22503-72-6
7 Unifiram 99% 272786-64-8
8 Noopept 99% 157115-85-0
9 pramiracetam 99% 68497-62-1
10 Piracetam 99% 7491-74-9
11 Oxiracetam 99% 62613-82-5
12 Aniracetam 99% 72432-10-1
13 L-Theanine 99% 3081-61-6
14 Alpha GPC 99% 28319-77-9
15 Sulbutiamine 99% 3286-46-2

 

 

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