Effective Anti-inflammatory Pharmaceutical Intermediate Loxoprofen Sodium Powder CAS: 80382-23-6

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: 80382-23-6
Minimum Order Quantity: 10g
Price: Contact Us
Packaging Details: Stealth And Discreet Packaging
Delivery Time: 7 work days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 1000kg per month
Product Name: Loxoprofen Sodium CAS: 80382-23-6
MF: C15H17NaO3 MW: 268.28
EINECS: 1806241-263-5 Uses: Anti-inflammatory
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pharmaceutical active ingredients

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pharmaceutical fine chemicals

 

Loxoprofen Sodium CAS: 80382-23-6

 

 

 

Basic Details:

Product Name: Loxoprofen sodium
Synonyms: alpha-methyl-4-((2-oxocyclopentyl)methyl)

benzeneacetatesodiumsaltdihydrate;benzeneaceticacid,alpha-methyl-4-((2-oxocyclopentyl)

methyl)-,sodiumsalt,di;cs-600;loxoprofensodium(patented-

nosupply);loxoprofensodiumdihydrate;sodium2-(4-(2-oxocyclopentylmethyl)phenyl)

propionatedihydrate;LOXOPROFEN SODIUM;sodium 2-[4-(2-oxocyclopentyl-1-methyl)phenyl]

propionate dihydrate
CAS: 80382-23-6
MF: C15H17NaO3
MW: 268.28
EINECS: 1806241-263-5
Uses anti-inflammatory
Definition ChEBI: A hydrate that is the dihydrate form of loxoprofen sodium. The parent

acid, loxoprofen, is a prodrug that is rapidly converted to its active trans-alcohol

metabolite following oral administration.

 

 

 

Description:
Loxoprofen sodium (CAS 80382-23-6): It is a non-steroidal anti-inflammatory drug which is

used for chronic and wet arthritis.

The Loxoprofen sodium, with the CAS registry number 80382-23-6, is also known as

Benzeneaceticacid, a-methyl-4-[(2-oxocyclopentyl)methyl]-, sodium salt (9CI). It belongs to

the product categories of APIS; Aromatics; Inhibitors; Intermediates & Fine Chemicals;

Pharmaceuticals. This chemical's molecular formula is C15H17NaO3 and molecular weight is

268.28. What's more, its systematic name is Sodium 2-{4-[(2-oxocyclopentyl) methyl]

phenyl}propanoate.

 

 

 

Application:
Used as anti-inflammatory drugs.Loxoprofen sodium is widely used in rheumatoid arthritis,

back pain, frozen shoulder, neck and wrist syndrome and other anti-inflammatory analgesic,

surgery, trauma and acute analgesic and anti-inflammatory airway inflammation after tooth

extraction solution heat analgesic.

 

 

Effective Anti-inflammatory Pharmaceutical Intermediate Loxoprofen Sodium Powder CAS: 80382-23-6 0

 

 

Specification:


Test Item

Analysis Specification

Result

Description

It occurs as white to yellowish white crystals or crystalline power

white crystalline power

Solubility

It is very soluble in water and in methanol, freely soluble in ethanol(95), and practically insoluble in diethyl ether

Meets

Optical Rotation

Not show optical rotation

Meets

Identification
A UV Absorption




B. IR Absorption



C. Sodium salt

A: Compare the spectrums between the solution of Loxoprofen Sodium and CRS, both spetra exhibit similar intensities of absorption at the same wavelengths.
B: Compare the infrared absorption spectrum of Loxoprofen Sodium with the reference spectrum; both spetra exhibit similar intensities of absorption at the same wavelengths.
C: A solution of Loxoprofen Sodium
(1~10) responds to the qualitative Tests for sodium salt

Meets


Meets




Meets

pH

6.5~8.5

7.9

Clarity and Color of solution

The solution is clear and colorless or pale yellow. The color is not darker than that of diluted Matching Fluid for Color A(1 in 2)

Clear and colorless

Heavy metals

≤10ppm

<10ppm

Related Substances

The spots other than the principal spot from the sample solution are not intense than the spot from the standard solution.

Meets

Water

11.0~13.0%

12.0%

Assay(Dry Basis)

≥98.5%

99.9%

Conclusion

Complies with requirements of JP15

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