Steroidal Antiandrogen Cyproterone acetate CAS: 427-51-0 For Producing Oral Contraceptive Pills

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: 427-51-0
Minimum Order Quantity: 10g
Price: Contact Us
Packaging Details: Stealth And Discreet Packaging
Delivery Time: 7 work days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 1000kg per month
Product Name: Cyproterone Acetate EINECS: 207-048-3
CAS: 427-51-0 MF: C24H29ClO4
MW: 416.94 Appearance: White Solid
High Light:

pharmaceutical active ingredients

,

pharmaceutical fine chemicals

Specification:

 

Cyproterone acetate

Synonyms: 1,2-alpha-methylene-6-chloro-delta-(sup4,6)-pregnadiene-17-alpha-ol-3,20-dio;1,2-alpha-methylene-6-chloro-delta(sup6)-17-alpha-hydroxyprogesteroneacetat;1,2-alpha-methylene-6-chloro-pregna-4,6-diene-3,20-dione17-alpha-acetate;17-alpha-acetoxy-6-chloro-1-alpha,2-alpha-methylenepregna-4,6-diene-3,20-dio;20-dione,6-chloro-17-hydroxy-1-alpha,2-alpha-methylene-pregna-6-diene-3;6)-pregnadiene-17-alpha-ol-3,20-dione17-2-alpha-methylene-6-chloro-(sup4;6-chlor-delta(sup6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteronacetat;6-chloro-1,2-alpha-methylene-17-alpha-hydroxy-delta(sup6)-progesteroneaceta
CAS: 427-51-0
MF: C24H29ClO4
MW: 416.94
EINECS: 207-048-3

Chemical Properties Crystalline Solid
Usage Used as an antiandrogen. Combinded with estrogen in the treatment of acne
Usage The free alcohol is an anti-androgen; the acetate is both an anti-androgen and a progestogen. Combined with estrogen it is used in the treatment of acne.
Usage antiparasitic, fasciolicide

 

 

Application:

CPA has been in use as an antiandrogen since 1964, and was the first antiandrogen introduced for clinical use. It is widely used throughout Europe, and is also used in Canada, Mexico, and other countries. It is not FDA-approved for use in the United States, due to concerns about hepatotoxicity; medroxyprogesterone acetate has been used in this country instead.

CPA has been approved for the treatment of prostate cancer, precocious puberty, androgen-related dermatological conditions (such as acne, seborrhea, hirsutism, and androgenic alopecia), and to reduce sex drive in sex offenders.Combination formulations of CPA with ethinyl estradiol (a formulation sometimes referred to as co-cyprindiol) have been available as contraceptives since 1997.

Other uses of CPA include the treatment of benign prostatic hyperplasia, priapism, hypersexuality, paraphilias, hot flashes, and hyperandrogenism in women. In addition, with the exception of the United States

 

COA:

 

Product Name Cyproterone Acetate Quantity 130kg
Batch No 160401 Packing Foil Bag
Produce Date 2016.04.01 Report Date 2016.04.02
Description White or almost white Crystalline Powder
Ref.Standard EP6 Standard
Results of Analysis Tests
Test Analysis Standard Results of Analysis
Identification Requirements Standard Conform
Melting Point About 210 210.5
Specific Rotation +152°~+157° +155°
Loss On Drying ≤0.5% 0.24%
Related Substance by HPLC ≤0.5%
Not more than 0.5%
0.3%
Assay 97.0-103.0% 99.8%
Sulphate ash ≤0.1%
Not more than 0.1%
0.035%
Conclusion The specification conform with EP6

 

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Steroidal Antiandrogen Cyproterone acetate  CAS: 427-51-0 For Producing Oral Contraceptive Pills 0
 

 

 
 
 
 

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