Effective Potassium-sparing Diuretic Triamterene CAS: 396-01-0 Yellow Solid Factory Directly Supply

Triamterene

Basic Details:

Product Name: Triamterene
Synonyms: 6-PHENYL-PTERIDINE-2,4,7-TRIAMINE;6-PHENYL-2,4,7-PTERIDINETRIAMINE;6-PHENYL-

2,4,7-TRIAMINO PTERIDINE;ADEMINE;2,4,7-TRIAMINO-6-PHENYLPTERIDINE;TRIAMTERENE;2,4,7-

triamino-6-fenilpteridina;2,4,7-triamino-6-phenyl-pteridin
CAS: 396-01-0
MF: C12H11N7
MW: 253.26
EINECS: 206-904-3
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Ion transporter and

other ion channel;Aromatics;Bases & Related Reagents;Nucleotides;DYRENIUM;Other APIs

Melting point 316°C
Fp 11 °C
storage temp. 2-8°C
solubility formic acid: soluble200 mg + 4 mL warm Formic Acid, clear, yellow-green
pka 6.2(at 25°C)
Water Solubility <0.1 G/100 ML AT 20°C
Appearance: Yellow Solid

Uses: 

1.Triamterene is a potassium-sparing diuretic ie, it inhibits the urinary excretion

of potassium
2. Triamterene is a weak diuretic with potassium sparing properties; blocks Na+

reuptake in the kidneys.

General Description Odorless yellow powder or crystalline solid. Melting point 316°C.

Almost tasteless at first and with a slightly bitter aftertaste. Acidified solutions give a

blue fluorescence. Used as a diuretic drug.

Air & Water Reactions Sensitive to light; slowly oxidized upon exposure to air. Insoluble

in water.

Reactivity Profile 2,4,7-Triamino-6-phenylpteridine neutralizes acids in exothermic

reactions to form salts plus water. May be incompatible with isocyanates, halogenated

organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable

gaseous hydrogen may be generated in combination with strong reducing agents, such as

hydrides.

Fire Hazard Flash point data for 2,4,7-Triamino-6-phenylpteridine are not available;

however, 2,4,7-Triamino-6-phenylpteridine is probably combustible.

Uses

Triamterene is a "water pill" (diuretic) that works in your kidneys to increase the amount of urine you make. This helps your body get rid of extra water. This medication is used to decrease swelling (edema) caused by conditions such as cancer, congestive heart failure, liver disease, and kidney disease. This effect can help your kidneys work better and lessen symptoms such as trouble breathing and swelling in your ankles, feet, hands, or belly.

How to use Triamterene Capsule

Take this medication by mouth as directed by your doctor, usually once or twice a day after a meal. If you take this drug too close to bedtime, you may need to wake up to urinate. It is best to take this medication at least 4 hours before your bedtime.

To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully.

The dosage is based on your medical condition and response to treatment.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.

Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased.

Tell your doctor if you do not get better or if you get worse.