New Non-Steroid Drug Flibanserin CAS: 167933-07-5 Aim At Boostering Women's Sexual Desire

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: 167933-07-5
Minimum Order Quantity: 10g
Price: Contact Us
Packaging Details: Stealth And Discreet Packaging
Delivery Time: Within 7 Working Days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 1000kg per month
Product Name: Flibanserin Synonyms: Bimt 17; BIMT 17BS
CAS: 167933-07-5 MF: C20H21F3N4O
MW: 390.4 Appearance: White Crystalline Powder
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Specification:

Product name Flibanserin
Other Name Addyi, Bimt; BIMT17BS; Flibanserin(BIMT17)
Original China
CAS 167933-07-5
Molecular formula C20H21F3N4O
MW 390.4
Brand name info@desen-nutrition.com
Leading time within 24 hours upon receipt of payment
Delivery Fast and secure shipping by EMS, DHL, TNT, FedEx, UPS
Purity 98% min.
Package Discreet and Hidden package according to specific requirement
Appearance White Powder
Certification SGS, ISO 9001, KOSHER
Payment Terms Western Union, Money Gram , T/T, Bitcoin
Minimum Order Quantity 5g
Price Negotiable
Usage A kind of drug being studied as a treatment for pre-menopausal women with hypoactive sexual desire disorder (HSDD).


Applications:

Flibanserin is used for hypoactive sexual desire disorder among women. Those receiving flibanserin report a 0.5 increase compared to placebo in the number of times they had "satisfying sexual events". In those on flibanserin it rose from 2.8 to 4.5 times a month while women receiving placebo reported also an increase of "satisfying sexual events" from 2.7 to 3.7 times a month. The onset of the flibanserin effect was seen from the first timepoint measured after 4 weeks of treatment and maintained throughout the treatment period.

 

The effectiveness of flibanserin was evaluated in three phase 3 clinical trials. Each of the three trials had two co-primary endpoints, one for satisfying sexual events (SSEs) and the other for sexual desire. Each of the 3 trials also had a secondary endpoint that measured distress related to sexual desire. All three trials showed that flibanserin produced a increase in the number of SSEs and reduced distress related to sexual desire. The first two trials used an electronic diary to measure sexual desire, and did not find an increase. These two trials also measured sexual desire using the Female Sexual Function index (FSFI) as a secondary endpoint, and a increase was observed using this latter measure. The FSFI was used as the co-primary endpoint for sexual desire in the third trial, and again showed a statistically significant increase.

 

Researchers think that flibanserin restores some of the chemical imbalances that affect sexual desire disorders. Most people have heard of antidepressants known as selective serotonin reuptake inhibitors, like fluoxetine (Prozac). SSRIs can have negative sexual side effects, such as reduced libido or erectile dysfunction. This suggests that serotonin plays an important role in sexual desire and excitation. Flibanserin affects serotonin but in a different way than SSRIs. It stimulates one type of receptor while blocking another, and it also increases dopamine in the body. Dopamine is known to have positive effects on sexual health.

 

COA :

 


Items
Specification
Appearance white crystals or crystalline powder, has a faint, characteristic odor and bitter taste
Solubility freely soluble in water and 95%ethanol, sparingly soluble in acetic anhydride and practically insoluble in diethyl ether
pH 3.5-4.5
Identification 1, red to dark purple color appears with(III)iron chloride
  2, light red precipitate formed with reinecke salt TS
  3, UV spectrum meet the reference
  4, solution (1%) responds to the qualitative test for chloride
Melting point 139-143 celcius degree
Clarity and color of solution clear and colorless
Sulfate 0.048%max
Heavy metals 10ppm max
As 2ppm max
Organic acid(0.1M NaOH) 0.54ml max
Loss on drying 0.5% max
Residue on ignition 0.1%max
Residual organic Solvents (GC) Xylol 0.217%max
  Isopropanol 0.5%max
Related substances(HPLC) Total impurity 1.5%max
  Single impurity0.5%max
  Free P-chloro phenoxy acetic 0.5%max
Count of bacteria bacillus 1000/1g max
  Mildew 100/1g max
  Microzyme 100/1g max
Assay(C12H16CINO3.HCl,on dry basis) 98%min


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New Non-Steroid Drug Flibanserin  CAS: 167933-07-5 Aim At Boostering Women's Sexual Desire 0

 
 
 
 

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