| Place of Origin: | CHINA |
|---|---|
| Brand Name: | TINGYI |
| Certification: | GMP , ISO 9001:2008 |
| Model Number: | 124750-99-8 |
| Minimum Order Quantity: | 100g |
| Price: | Contact Us |
| Packaging Details: | Stealth And Discreet Packaging |
| Delivery Time: | Within 7 Working Days |
| Payment Terms: | Bank Transfer - Bitcoin - Western Union - MoneyGram |
| Supply Ability: | 1000kg per month |
| Product Name: | Losartan Potassium | CAS: | 124750-99-8 |
|---|---|---|---|
| MF: | C22H23ClKN6O | MW: | 462.01 |
| Appearance: | White To Off-White Crystalline Powder | ||
| High Light: | pharmaceutical active ingredients,pharmaceutical fine chemicals |
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| Product Name: | Losartan potassium |
| Synonyms: | 2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOL-5YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOL;2-butyl-4-chloro-1-[[2'-(1h-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1h-imidazole-5-methanol monopotassium salt;2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOLE-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOL, POTASSIUM SALT;COZAAR;DUP 753;LOSARTAN MONOPOTASSIUM SALT;LOSARTAN POTASSIUM;LOSARTAN POTASSIUM SALT |
| CAS: | 124750-99-8 |
| MF: | C22H23ClKN6O |
| MW: | 462.01 |
| EINECS: | 200-287-4 |
| Product Categories: | Hypertension;Intermediates & Fine Chemicals;Pharmaceuticals;Losartan;APIS;Aromatics;Heterocycles;API Reference Standard;COZAAR;Cardiovascular APIs;API |
| Mol File: | 124750-99-8.mol |
| Melting point | 263-265°C |
| storage temp. | Desiccate at RT |
| Merck | 14,5583 |
| InChIKey | OXCMYAYHXIHQOA-UHFFFAOYSA-N |
| CAS DataBase Reference | 124750-99-8(CAS DataBase Reference) |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| RTECS | NI6755100 |
| Hazardous Substances Data | 124750-99-8(Hazardous Substances Data) |
| Description | As a angiotensin II receptor antagonist, Losartan Potassium is the potassium salt of losartan with antihypertensive activity, which is mainly used in the therapy of high blood pressure (hypertension) and diabetic nephropathy. It functions by relaxing blood vessels so that blood can flow more easily. It is also effective to help protect the kidneys from damage caused by diabetes and lower the risks of stroke in patients suffering from hypertension and myocardial enlargement. Besides, recent study has suggested that losartan is beneficial to reverse age related dysfunction in maintaining normal blood pressure and cellular energy usage on mitochondria and it can probably be used to treat left ventricular hypertrophy. It may also be used as an alternative agent for the treatment of systolic dysfunction, myocardial infarction, coronary artery disease, and heart failure. |
| Chemical Properties | White to Off-White Crystalline Powder |
| Uses | A nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive. |
| Uses | antihypertensive, AT1 angiotensin II antagonist |
| Uses | Coronary vasodilator used in the diagnosis of coronary heart disease (adenosine A2A agonist). |
| Brand name | Cozaar (Merck). |
| Biological Activity | Selective non-peptide angiotensin AT 1 receptor antagonist. Inhibits the contractile effects of angiotensin II on rabbit aorta and jugular vein (pA 2 = 8.27). Orally active antihypertensive agent. |
