100% High Quality Emergency Contraception Drug Raw Powder Levonorgestrel CAS: 797-63-7

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: 797-63-7
Minimum Order Quantity: 10g
Price: Contact Us
Packaging Details: Stealth And Discreet Packaging
Delivery Time: Within 7 Working Days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 50 KG/Month
Product Name: Levonorgestrel CAS: 797-63-7
MF: C21H28O2 MW: 312.45
EINECS: 212-349-8 Appearance: White Solid
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100% High Quality Emergency Contraception Drug Raw Powder Levonorgestrel CAS: 797-63-7 0

 

Levonorgestrel

 

 

Basic Information:

Product Name: Levonorgestrel
Synonyms: 13-ethyl-17-alpha-ethynyl-17-beta-hydroxy-4-gonen-3-one;13-ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one;13-ethyl-17-hydroxy-19-dinor-17-alpha-pregn-4-en-20-yn-3-on(+)-1;17-alpha-ethinyl-13-beta-ethyl-17-beta-hydroxy-4-estren-3-one;17-beta-hydroxy-18-methyl-19-nor-17-alpha-pregn-4-en-20-yn-3-one;17-ethynyl-18-methyl-19-nortestosteron;17-ethynyl-18-methyl-19-nortestosterone;18-methyl-17-alpha-ethynyl-19-nortestosterone
CAS: 797-63-7
MF: C21H28O2
MW: 312.45
EINECS: 212-349-8
Melting point 206°C
alpha D20 -32.4° (c = 0.496 in CHCl3)
storage temp. 2-8°C
appearance White Solid

 

 

Description:
Oral Contraceptive Levonorgestre, also called D-norgestre and left Kanok ketone, is known as the most widely used oral contraceptives currently. It is the optically active part of racemic norgestrel. With activity twice as strong as norethindrone, when the dose is reduced by half, its adverse reactions will reduce correspondingly. Besides it has rapid oral absorption that can reach the peak within 0.5~1h with t1/2 of 10~24 h, protein binding rate of 93% to 95% and high bioavailability. It mainly distributed in liver, kidney, ovarian and uterine body's organs and tissues, and its metabolites, mainly in the form of glucuronide and sulfate salts, excrete from the urine and feces. It combined with ethinyl estradiol to be short-acting oral contraceptives. Its biphasil and triphasil have fewer adverse reactions, and are more closer to women normal hormone secretion type. They can be used for emergency contraception even in post-coital contraception without protective measures or failed contraception (condom slippage or breakage, coitus out of control, rhythm miscalculation, etc.). As the triphasil reduces this product by 40%, there will be less adverse reactions. If Levonorgestrel`s dosage form is changed, it can also be used as a variety of long-acting contraceptives. Used as a short-acting oral contraceptives: From the 5th day of menstruation start taking compound levonorgestrel tablets, one tablet a day for 22 days without interruption, before bedtime. After serving so on the 5th day of the next menstruation, continue the medication. The users may have nausea, vomiting, headache, breast fullness after serving, acne, weight gain, depression, lowered HDL, breakthrough bleeding, amenorrhea, etc. Liver and kidney dysfunction, breast lumps patients are prohibit taking it. Not suitable for use as regular birth control pills, reliable contraceptive measures should be taken to the next pre-menstrual after taking the drug. Women who smoke should not take it (due to easily complication of cardiovascular disease).
Uses Progestin drugs for irregular menstruation, functional uterine bleeding, endometriosis, etc.

 

 

Usage:
1. An emergency contraceptive. Levonorgestrel is safe, tolerated and effective in emergency contraception in woman
2. progestin

 

 

Application:
 

1.Oral contraception
At low doses, levonorgestrel is used in monophasic and triphasic formulations of combined oral contraceptive pills, with available monophasic doses ranging from 100-250 μ G, and triphasic doses of 50 μ G/75 μ G/125 μ G.
At very low daily dose of 30 μ G, levonorgestrel is used in some progestogen only pill formulations.

 

2.Emergency contraception
Levonorgestrel is used in emergency contraceptive pills (ECPs), both in a combined Yuzpe regimen which includes estrogen, and as a levonorgestrel-only method. The levonorgestrel-only method uses levonorgestrel 1.5 mg (as a single dose or as two 0.75 mg doses 12 hours apart) taken within 3 days of unprotected sex, with one study indicating that beginning as late as 120 hours (5 days) after intercourse could be effective.

 

3.Intrauterine system
Levonorgestrel is the active ingredient in the Mirena & Skyla (Jaydess) intrauterine system.

 

4.Contraceptive implants
Levonorgestrel is the active ingredient in Norplant and Jadelle.

 

5.Hormone replacement therapy
Levenorgestrel is combined with 17-beta estradiol in the Climara Pro hormonal patch.

 

 

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