Pharmaceutical Raw Materials Yellow Powder Tretinoin CAS 302-79-4 Antineoplast Anti Inflammatory and Treat Acne

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: CAS: 302-79-4
Minimum Order Quantity: 10g
Price: Contact Us
Packaging Details: Stealth and discreet packaging
Delivery Time: Usually within 7 work days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 3000KG/Month
Product Name: Tretinoin CAS: 302-79-4
MF: C20H28O2 MW: 300.44
EINECS: 206-129-0 Appearance: Yellow Powder
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Product Name: Tretinoin

 

Quick detial :

 

 

Product name

 

Tretinoin

 

Other name

 

ALL-TRANS;RETINOIC ACID;RETINOIC ACID, ALL TRANS

 

CAS

 

302-79-4

 

MF

 

C20H28O2

 

MW

 

300.44

 

Content

 

98.0--102.5%

 

Melting point

 

179-186 º C

 

Boiling point

 

462.8 ° Cat 780 mmHg

 

Water soluble

 

Insoluble
Molecular structure Active Pharmaceutical Intermediates Powder Tretinoin CAS 302-79-4 to Treat Acne

 

Assay

 

99%

 

Appearance:

 

Yellow-Orange Powder

 

Usage

 

keratolytic, antiacne, antineoplastic

 

 

Description:

 

1). Tretinoin is commonly used in dermatology drugs, which is the department of vitamin A (Victoria methanol) metabolic intermediates.It mainly affects the growth of bones and epithelial metabolism, can promote epithelial cell proliferation and updates, and can inhibit the proliferation and differentiation of keratinocytes, so hyperkeratosis can be back to normal.

2). Therefore many complete or incomplete keratosis, hyperkeratosis of diseases have a certain therapeutic effect, treat a variety of skin diseases. The use of the drug can penetrate topical skin quickly, enable significantly increased epithelial cell turnover. This class of drugs has strong and rapid inhibition on the secretion of the sebaceous glands, can reduce sebum secretion. In addition, the product also has anti-tumor, promote wound healing and anti-inflammatory effects.

3). It is a yellow needle crystal, with a similar smell of vitamin acetate. Soluble in methanol, ethanol, acetone, also in vegetable oil and fatty. In case of light, it is thermal instability, suck up moisture in the air, polymerization and metamorphism in water. The melting point of all trans-vitamin A acid is 182 ~ 180°C, the melting range of which is mixed with a small amount of isomers is 170 ~ 190°C.

4). This product can induce epidermal hyperplasia, and improve the granular layer and the cell layer thickness.It can influence the silk protein process and the formation of cross-linked film and promote the differentiation of epidermal granular layer cells in the late stage of the differentiation of the epidermal cells by affecting K10, K1 keratin solution.

 

 

Application:

 

(1) Applies to abnormal tyshiyongyupe of acne, fish phosphorus disease and abnormal psoriasis.
(2) Resistance to abnormal skin drugs.
(3) Tretinoin mainly affects the growth of bones and epithelial metabolism, can promote epithelial cell proliferation and updates, and can inhibit the proliferation and differentiation of keratinocytes, so hyperkeratosis can be back to normal. Therefore many complete or incomplete keratosis, hyperkeratosis of diseases have a certain therapeutic effect, treat a variety of skin diseases. Tretinoin is mainly used in the treatment of psoriasis, ichthyosis, follicular keratosis, acne, lichen planus, verrucous epidermal nevus, impetigo, vitiligo, lichen psoriasis, the face of pityriasis alba, etc.

Tretinoin can increase the cell nucleus division and epidermal cell turnover, form of the stratum corneum cell adhesion, and easy to fall off. It can remove the existing acne, while inhibiting the formation of new acne, hair follicle epithelial replacement can prevent the blockage of the plug. The synthesis of keratin is also inhibited, which can affect the metabolism of epithelial cells. It has the effect of promoting the proliferation and differentiation of epithelial cells, and the dissolution of keratinocytes. It is used in the treatment of acne vulgaris, especially the blackhead acne lesions, senile, fluorescent or drug skin atrophy, ichthyosis and various abnormal keratinization and pigment excessive calm skin disease, and psoriasis.

Tretinoin is commonly used in dermatology drugs, which is the department of vitamin A (Victoria methanol) metabolic intermediates.It mainly affects the growth of bones and epithelial metabolism, can promote epithelial cell proliferation and updates, and can inhibit the proliferation and differentiation of keratinocytes, so hyperkeratosis can be back to normal. Therefore many complete or incomplete keratosis, hyperkeratosis of diseases have a certain therapeutic effect, treat a variety of skin diseases. The use of the drug can penetrate topical skin quickly, enable significantly increased epithelial cell turnover. This class of drugs has strong and rapid inhibition on the secretion of the sebaceous glands, can reduce sebum secretion. In addition, the product also has anti-tumor, promote wound healing and anti-inflammatory effects.

Used in abnormal acne, ichthyosis and abnormal type of psoriasis. For the treatment of acne vulgaris, psoriasis,
ichthyosis, lichen planus, Mao Fahong rosea, follicular keratosis, squamous cell carcinoma and melanoma, disease.
Pharmacology: Epidermal keratinocytes, dermal melanin cells and fibroblasts are the target cells of A retinoic acid
important. A retinoic acid can affect the formation of melanin melanin cells, its role is more than point, has
inhibitory effect on tyrosine hydroxylase, Doba oxidase and two hydroxyindole oxidase three catalytic activity,
thereby reducing the formation of melanin, reduce skin pigmentation.

 

Pharmaceutical Raw Materials Yellow Powder Tretinoin CAS 302-79-4  Antineoplast Anti Inflammatory and Treat Acne 1

 

 

COA:

 

 

Assay Content HPLC

 

98% 98.12%

 

Appearance

 

Yellow Powder Complies

 

Odor

 

Characteristic Complies

 

Mesh

 

100% pass 100 mesh Complies

 

Residue on ignition

 

MAX 0.1% Complies

 

Loss on drying %

 

MAX 0.5% 0.39%

 

Ash %

 

MAX.1.0% 0.52%

 

Heavy metals PPM

 

MAX.0.002% Complies
Microbiology
Total Plate Count
Yeast & Mold
E.Coli
Salmonella

<1000cfu/g
<100cfu/g
Negative
Negative

82cfu/g
Negative
Complies
Complies

 

Packing description

 

Sealed export grade drum & double of sealed plastic bag
Storage Store in cool & dry place not freeze., keep away from strong light and heat
Shelf life

 

2 years when properly stored
 

 

 

Function:

 

1). Used for usual acne, lichen planus, white spot, hair red pityriasis and facial pityriasis simplex
2). Also can be used as an auxiliary therapy for psoriasis.
3). Can also be used in the treatment of multiple verruca vulgaris, and abnormal keratinization of various skin
diseases such as ichthyosis, hair follicle keratinization disorder
4). For cancer prevention and treatment of precancerous lesions, Such as white spot of the oral mucosa, laryngeal
papilloma, stunting disease
5). Used for skin malignant tumor such as squamous cell carcinomas and basal cell carcinoma, mycosis enzyme disease
6). For acute early young granulocyte leukemia.

 

 

Dosage:

 

(1) ointment: use 0.1% ointment for the other skin lesions and 0.05% ointment for acne skin lesions in the topical application. Clean the skin with warm water after one time every night.

 

(2) gel: apply to the affected area. At the beginning of treatment , it can be taken one time every two days or every three days. Afterwards smear one time every night.

 

 

Our Company Advantages:

 

1, High quality with competitive price:

1) Standard: U.S Standard
2) All Purity≥99.8%
3) We are manufacturer and can provide high quality products with factory price.


2, Fast and safe delivery
1) Parcel can be sent out within 8 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99.8%
4)We provide re-ship policy.
5) We have warehouse in Australia, Canada and England, we have large amounts of stock in the warehouse, can ship to you directly from our foreign warehouse!
3, We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

 

 

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