Effective Chemotherapy Drug Idebenone Powder CAS: 58186-27-9 Used For Cognition Enhancer And Nootropic

Idebenone

Basic Information:

Product Name: Idebenone
Synonyms: 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-

benzoquinone;Avan;Daruma;Mnesis;IDEBENONE(PATENTED-NOSUPPLY);5,6-Dimethoxy-2-(10-

hydroxydecyl)-3-methyl-1,4-benzoquinone;5,6-dimethoxy-2-(10-hydroxydecyl)-3-methyl-5-

cyclohexadiene-1,4-dione;cv 2619 idebenone
CAS: 58186-27-9
MF: C19H30O5
MW: 338.44
EINECS: 1308068-626-2
Melting point: 52-55°C
Storage temp: Room temp
Appearance: Yellow-Orange Crystalline Solid

Description:
Idebenone is an organic compound belonging to the quinone family, being similar to coenzyme

Q-10. It is a kind of drug developed by Takeda Pharmaceutical Company for the treatment of

Alzheimer’s disease and some other cognitive defects. However, these have been not very

much progress associated with this indication. It is now also used for the treatment of

Friedreich’s ataxia with a positive effect on cardiac hypertrophy and neurological

function. However, this indication is only approved in Canada, not in Europe and US. It is

now under investigation on its efficacy for the treatment of Duchenne muscular dystrophy,

Leber’s hereditary optic neuropathy, mitochondrial encephalomyopathy, lactic acidosis, and

stroke-like episodes) as well as primary progressive multiple sclerosis. The efficacy of

this drug still demands more evidences.

Uses:
1. cognition enhancer, nootropic
2. chemotherapy drug
3. Ubiquinone derivative with protective effects against cerebral ischemia. Nootropic

Definition ChEBI:
A member of the class of 1,4-benzoquinones which is substituted by methoxy groups at

positions 2 and 3, by a methyl group at positions 5, and by a 10-hydroxydecyl group at

positions 6. Initially developed for the treatment of Alzheimer's disease, benefits ere

modest; it was subsequently found to be of benefit for the symptomatic treatment of

Friedreich's ataxia.

Biological Activity:
Antioxidant and neuroprotective agent. Protects mitochondrial membranes against lipid

peroxidation and blocks glutamate neurotoxicity in vitro and in vivo . Inhibits apoptosis

of astrocytes via increased NGF production.

Usage:
1. Brain function enhancer, can improve brain energy metabolism, improve brain function, and a mild antihypertensive effect. Clinical for cerebral infarction, cerebral hemorrhage and atherosclerosis sequelae caused by brain dysfunction, low consciousness, mood disorders, language disorders, dementia and other patients.
 

2. Central nervous system stimulant.
 

3. Used as a brain circulation to improve drugs, intelligence promotion drugs