99% Purity White SARMS Raw Powder Nootropics Coluracetam CAS 135403-81-9 for Memory Enhancing

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: CAS: 135463-81-9
Minimum Order Quantity: 10g
Price: Contact Us
Packaging Details: Stealth and discreet packaging
Delivery Time: Usually within 7 work days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 3000KG/Month
Product Name: Coluracetam MKC-231 CAS: 135463-81-9
MF: C19H23N3O3 MW: 341.4
Assay: 99% Appearance: White Powder
High Light:

pharmaceutical anabolic steroids

,

pharmaceutical fine chemicals

Product Name: Coluracetam MKC-231

 

Product details:

 

 

Product Name

 

Coluracetam MKC-231
Chemical Name
  1. N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-
  2. 1-yl)acetamide

 

CAS

 

135463-81-9

 

Molecular Formula

 

C19H23N3O3

 

Molecular Weight

 

341.4

 

Boiling Point

 

634.1C at 760 mmHg C

 

Apperance

 

White Powder

 

Assay

 

99%

 

Grade

 

Pharmaceutical Grade

 

 

Description:

 

Coluracetam (BCI-540) is a nootropic drug of the racetam family.Coluracetam (formerly known as MKC-231) was initially developed and tested by the Mitsubishi Tanabe Pharma Corporation for Alzheimer's disease. Coluracetam enhances high-affinity choline uptake (HACU) which is the rate-limiting step of acetylcholine (ACh) synthesis, and is the only known choline uptake enhancer to currently exist. Studies have shown Coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects by changing the choline transporter regulation system.

 

After the drug failed to reach endpoints in its clinical trials it was in-licensed by BrainCells Inc for investigations into major depression disorder (MDD), after being awarded a "Qualifying Therapeutic Discovery Program Grant" by the state of California.

Findings from its Phase 2a clinical trials have suggested that it would be an ideal medication for co-morbid MDD with generalized anxiety disorder (GAD). BrainCells Inc is currently out-licensing the drug for this purpose. It may also have potential use in prevention and treatment of ischemic retinopathy and retinal and optic nerve injury.

 

 

Application:

 

Rat studies have shown that Coluracetam is helpful in reducing the effects of learning deficits. Not only did Coluracetam reduce these effects, but Coluracetam also did not have any of the normally expected side effects. This product is also considered to have great potential as a casual mood enhancer and a powerful memory booster. There is even evidence to suggest that the positive effects on the brain are semi-permanent Users also report a rather wide range of Coluracetam benefits. This includes enhanced concentration and speed of cognition. Coluracetam also helps with both short and medium term memory. There are also a number of reports of being able to study and focus more easily while taking this nootropic. Coluracetam also seems to have a bit of a stimulant effect. It should help to shake off any of the morning dreariness if taken upon waking and it may produce a nice, comfortable energy boost that can last well into the day. A number of users have reported that this is able to help them improve their motivation and ability to get things done. Another interesting effect is the apparent enhancement of sounds and colors. This can be compared to turning up the brightness on a TV or computer screen, with sounds become fuller and richer.

Coluracetam enhances high-affinity choline uptake (HACU) which is the rate-limiting step of acetylcholine (ACh) synthesis, and is the only known choline uptake enhancer to currently exist. Studies have shown Coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects by changing the choline transporter regulation system.

 

Memory and Learning

Coluracetam is shown to improve cognitive function and memory in rats, and in theory, the same results are expected in human beings. A study conducted by BrainCells Inc, showed a memory improvement in rats who were given substance AF64A (a neuron-specific neurotoxin) for 8 days along with Coluracetam in 3mg doses. These rats were put through the standardized Morris Water Maze to mark their ability to get through it, and even up to 72 hours after the last 8mg dose, they were still able to. Another key finding of this study was that the results were still apparent 3 days after the last dose, even though the serum concentration of Coluracetam was negligible.

 

Depression and Anxiety

BrainCells Inc, found that a dosage of 240mg (split into three daily doses of 80mg) was useful in treating major depression co-morbid with GAD (generalized anxiety disorder). However, the differences were most pronounced in those who didn't find relief in using standard antidepressants. After one dose, there were no noticeable differences, but after 2 doses at 80mg, 36% had improved scores during a depression assessment test.

 

Eyesight

Coluracetam has been associated with optic benefits such as enhanced color vision, recognition and vividness. Although there isn't any conclusive evidence to support the mechanisms behind this benefit, experts believe that Coluracetam works in the part of the brain that runs visual processes.

 

99% Purity White SARMS Raw Powder Nootropics Coluracetam CAS 135403-81-9  for Memory Enhancing 0

 

 

COA:

 

Analysis Test Specification Result
Description white crystalline powder,odorless Conforms
Solubility Easily soluble in water, unsoluble in ethanol Conforms
PH 6.0~7.5 6.9
Solution clarity and color solution should be clear and colorless Conforms
Related substances

5’CMP 0.3%

Simple impurity

Total other impurity

0.01%

0.03%

0.10%

Chloride 0.05% Conforms
Ammonium 0.05% Conforms
 

Fe

0.01%  

Conforms

Phosphate 0.1% Conforms
Loss on drying ≤6.0% 1.3%
Heavy metals 0.002% Conforms
Arsenide 0.0001% Conforms
Bacterial Endotoxins 0.3EU/mg Conforms
Microbial Limit Conforms Conforms
Assay(on dried basis) ≥99.0% 99.8%
 

 

 

Function:

 

Enhance mental intelligence

Boost memory and leaning capabilities

Improve brain power to solve problems and protect it from any chemical or physical injury

Enhance motivation level

Enhance the control of cortical/subcortical brain mechanism

Improve sensory perception

 

 

Dosage:

 

Since the study subjects were rats, there aren't any recommended human dosages, but there is a general guideline for conversion. In rats, the dosage ranged between 1 mg/kg and 10 mg/kg per day. By using allometric scaling, the dose becomes 2.9 mg/kg in humans, so the average dose should not exceed 203.5 mg daily for someone in a typical weight class. There isn't information to indicate toxicity of Coluracetam, although doses given at the above increments showed no negative side effects. If you haven't used a nootropic before, you may develop headache after use, which is a common in first time users. By stacking the Coluracetam with Choline, you'll reduce this risk.

 
 
Our Company Advantages:

 

1, High quality with competitive price:

1) Standard: U.S Standard
2) All Purity≥99.8%
3) We are manufacturer and can provide high quality products with factory price.


2, Fast and safe delivery
1) Parcel can be sent out within 8 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99.8%
4)We provide re-ship policy.
5) We have warehouse in Australia, Canada and England, we have large amounts of stock in the warehouse, can ship to you directly from our foreign warehouse!
3, We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

 

 

Our Other Products:

 

Testosterone Steroid

 

 

No.

CAS NO

Name

1

CAS:58-22-0

Testosterone base

3

CAS:76-43-7

Fluoxymesterone Halotestin

4

CAS:2446-23-3

4-Chlorodehydromethyltestosterone(Oral turinabol)

5

CAS:1255-49-8

Testosterone Phenylpropionate

6

CAS:57-85-2

Testosterone Propionate

7

CAS:1045-69-8

Testosterone acetate

8

CAS:315-37-7

Testosterone enanthate

9

CAS:58-20-8

Testosterone Cypionate

10

CAS:1424-00-6

Mesterolone (Proviron)

11

CAS:5949-44-0

Testosterone Undecanoate

12

CAS:15262-86-9

Testosterone isocaproate

13

CAS:855-19-6

Turinabol(4-Chlorotestosterone/Clostebol Acetate)

14

CAS: NO

Testosterone Sustanon 250/100

15

CAS:5721-91-5

Testosterone decanoate

16

CAS:58-18-4

Methyltestosterone (17-methyltestosterone)

17

CAS:58-20-8

1-Test Cyp,Dihydroboldenone Cypionate

Boldenone Steroid

 

 

17

CAS:846-48-0

Boldenone

18

CAS:13103-34-9

Boldenone Undecylenate (Equipoise)

19

CAS:846-46-0

Boldenone Acetate

20

CAS:13103-34-9

Boldenone Propionate

21

CAS:106505-90-2

Boldenone Cypionate

Trenbolone Steroid

 

 

22

CAS:10161-33-8

Trenbolone base

23

CAS:10161-34-9

Trenbolone acetate(Finaplix H/Revalor-H)

24

CAS:472-61-546

Trenbolone enanthate(parabolan)

25

CAS:23454-33-3

Trenbolone Hexahydrobenzyl Carbonate

Nandrolone Steroid

 

 

26

CAS:434-22-0

Nandrolone

27

CAS:62-90-8

Nandrolone Phenypropionate (NPP)/durabolin

28

CAS: 601-63-8

Nandrolone cypionate

29

CAS:360-70-3

Nandrolone decanoate(DECA)/ Deca durabolin

30

CAS: 862-89-5

Nandrolone Undecylate

31

CAS: 7207-92-3

Nandrolone propionate

Primobolan Steroid

 

 

32

CAS:434-05-9

Methenolone Acetate(Primobolan)

33

CAS:303-42-4

Methenolone enanthate (USAN)

34

CAS: 153-00-4

Metenolone

35

CAS:3381-88-2

Superdrol Powder/Methasterone (methyl-drostanolone)

36

CAS:521-12-0

Drostanolone Propionate (Masteron)

37

CAS:472-61-145

Drostanolone Enanthate(Masteron)

Anabolic Steroids

 

 

38

CAS:72-63-9

Methandrostenolone (Dianabol, methandienone)

39

CAS:3704-09-4  

Mibolerone

40

CAS:965-93-5

Methyltrienolone (Metribolone)

41

CAS:5197-58-0

Methylstenbolone

42

CAS: 5630-53-5

Tibolone

43

CAS:521-11-9

Mestanolone

44

CAS:521-18-6

Stanolone (androstanolone)

45

CAS:434-07-1

Oxymetholone (Anadrol)

46

CAS:53-39-4

Oxandrolone(Anavar)

47

CAS:10418-03-8

stanozolol(Winstrol)

48

CAS:6157-87-5

Trestolone acetate

49

CAS:853-23-6

Dehydroisoandrosterone 3-acetate

50

CAS:53-43-0

Dehydroepiandrosterone (DHEA)

51

CAS:481-29-8

Epiandrosterone

52

CAS:566-19-8

7-Keto-dehydroepiandrosterone

53

CAS:76822-24-7

1-DHEA

 

 

Other hot-selling steroids and peptides:

 

Testosterone Acetate

Trenbolone Acetate

MGF

Testosterone Cypionate

Trenbolone Enanthate

PEG MGF

Testosterone Decanoate

Boldenone Acetate

CJC-1295

Testosterone Enanthate

Boldenone undecylenate

CJC-1295 DAC

Testosterone Isocaproate

Boldenone Cypionate

PT-141

Testosterone Phenylpropionate

Boldenone Propionate

Melanotan-1

Testosterone Propionate

Nandrolone Decanoate

Melanotan-2

Testosterone Undecanoate

Nandrolone phenylpropionate

GHRP-2

Mesterone

Nandrolone undecylate

GHRP-6

Testosterone Sustanon 250

Nandrolone cypionate

Ipamorelin

Clostebol Acetate

Nandrolone propionate

Hexarelin

Methylandrostanolone

Methyltrienolone

Sermorelin

Methenolone Enanthate

Drostanolone Propionate

Oxytocin

Methenolone Acetate

Drostanolone Enanthate

TB500

Anadrol

Stanolone

Fragment 176-191

Anavar

Tadalafil

Triptorelin

Winstrol

Vardenafil

Tesamorelin

Clomifene citrate

Dianabol

Gonadorelin

Toremifene citrate

Tamoxifen Citrate

DSIP

Finasteride

hydrochloride

Selank

Benzocaine

Liothyronine sodium T3

L-Carnitine

Contact Details
Sales Manager

WhatsApp : +8613657291547