| Place of Origin: | CHINA |
|---|---|
| Brand Name: | TINGYI |
| Certification: | GMP , ISO 9001:2008 |
| Model Number: | CAS: 93957-55-2 |
| Minimum Order Quantity: | 10g |
| Price: | Contact Us |
| Packaging Details: | Stealth and discreet packaging |
| Delivery Time: | Usually within 7 work days |
| Payment Terms: | Bank Transfer - Bitcoin - Western Union - MoneyGram |
| Supply Ability: | 3000KG/Month |
| Product Name: | Fluvastatin Sodium | CAS: | 93957-55-2 |
|---|---|---|---|
| MF: | C24H25FNNaO4 | MW: | 433.45 |
| Assay: | 99% | Appearance: | Yellow Powder |
| High Light: | pharmaceutical active ingredients,pharmaceutical anabolic steroids |
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Product Name: Fluvastatin Sodium
Product Details:
| Product Name: | Fluvastatin Sodium |
| CAS Number: | 93957-55-2 |
| Assay: | 99% |
| Formula: | C24H25FNNaO4 |
| Molecular Weight: | 433.45 |
| Melting Point: | 194-197 ° C |
| Boiling Point: | 681.8 ° C at 760 mmHg |
| Flash Point: | 366.1 ° C |
| Appearance: | Yellow powder |
| Grade: | Pharmaceutical Grade |
|
Storage temp
|
Desiccate at -20°C |
| Usage |
A synthetic HMG-CoA reductase inhibitor. Antilipemic Anti-hyperlipoproteinemic;'HMG CoA reductase inhibitor |
Description:
Fluvastatin is an inhibitor of HMG-CoA reductase that is clinically used to lower cholesterol and treat cardiovascular disease. Fluvastatin exhibits anti-hyperlipidemic, anti-fibrotic, cardioprotective, antiviral, antithrombotic, antioxidative, vasorelaxant, anti-atherosclerotic, and anticancer activities. Fluvastatin suppresses viral load of hepatitis C virus in a clinical setting and prevents viral replication. In vitro, fluvastatin decreases platelet activation by increasing PECAM-1 signaling and inhibiting activation of Akt. Additionally, fluvastatin scavenges hydroxyl radicals in vitro. In other cellular models, fluvastatin increases expression of NO and phospholipase 2 (PLA2) and decreases levels of angiotensin II (AT II) and ROCK. Additionally, this compound induces apoptosis and G2/M phase cell cycle arrest, decreases the mitochondrial membrane potential, and increases release of cytochrome c and activation of caspase 3 in hepatocellular carcinoma cells. In animal models of cardiac distress, fluvastatin improves left ventricular function and prevent fibrosis by inhibiting RhoA and decreasing levels of CTFG and fibronectin.
Fluvastatin Sodium salt of formula I (relative stereochemistry) is marketed by Novartis under the trade name of Lescol and belongs to a class of anti-hyperlipidemic agents called statins. Such compounds are HMG-COA reductase inhibitors, i.e. inhibit the enzyme that reduces 3-hydroxy-3-methylglutaric acid to mevalonic acid, thus blocking the biosynthesis of cholesterol and lowering its level in the bloodstream. Most statins resemble mevalonic acid in the sense that they contain the 3,5-dihydroxy carboxylate function, fooling the enzyme to binding to the drug and therefore inhibiting it.
Usage:
Fluvastatin sodium salt is commonly used as a cholesterol-lowering drug, cholesterol-lowering effect is very good, the trade name of the commercially available products is Lescol,which is produced by Novartis. Fluvastatin sodium salt is a fully synthetic cholesterol-lowering drug, it belongs to methylglutaryl coenzyme A (HMC-CoA) reductase inhibitors, the main function is performed in the liver ,it can transform HMG-CoA into 3-methyl - 3,5-dihydroxy acid, it can inhibit the synthesis of endogenous cholesterol ,and reduce cholesterol content in liver cells, it can stimulate the synthesis of low density lipoprotein (LDL) receptors,and enhance the uptake of LDL particles, reduce the plasma total cholesterol concentration.it can significantly reduce total cholesterol, LDL cholesterol, triglycerides, and increase high-density lipoprotein cholesterol.
Our Company Advantages:
1, High quality with competitive price:
1) Standard: U.S Standard
2) All Purity≥99.8%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out within 8 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99.8%
4)We provide re-ship policy.
5) We have warehouse in Australia, Canada and England, we have large amounts of stock in the warehouse, can ship to you directly from our foreign warehouse!
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1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
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