99% Nootropic Powder Vinpocetine CAS 42971-09-5 For Brain Health Supplement and Cerebrovascular Expansion

Product Name: Vinpocetine

Product Details:

Description:

Vinpocetine is a derivative of Vincamine, which is extracted from the Periwinkle plant ( Vinca Minor, Vinca Pervinca ). Research suggests that Vinpocetine helps to maintain healthy blood circulation in the brain and supports certain neurotransmitters in the memory process. Vinpocetine supports and protects brain blood vessel health and aids mental function.

(1) Vinpocetine is a cerebrovascular expansion drug and has a relatively stronger function than Vincamine. It can selectively increase cerebral blood flow, enhance and improve brain oxygen supply, promote metabolism, enhance the capacity of deformation for red blood cells, reduce blood viscosity, inhibit platelet aggregation, improve tissue metabolism.
(2) Vinpocetine is mainly used in the treatment of cerebral infarction sequela, cerebral hemorrhage sequelae, cerebral arteriosclerosis, etc. It can also used in the treatment of retinal vascular sclerosis and blood vessel spasm, the elderly deafness, and dizziness.
(3) Vinpocetine is a half synthetic Vincamine derivative, and has the similar effect with Vincamine. It has a stronger expansion function for cerebrovascular selectively.

Pharmacological effects are as follows:
Inhibit the activity of calcium dependency phosphodiesterase, increase the content of cAMP which can relax vascular smooth muscle, then relax vascular smooth muscle, and further increase cerebral blood flow. Enhance the capacity of deformation of red blood cells, reduce blood viscosity, inhibit platelet aggregation, and thus improve blood flow and microcirculation. Promote the brain tissue to absorb glucose, and promote the transformation of brain monoamine metabolism. Inhibit the increase of brain lactic acid during cerebral ischemia, increase the ATP content, inhibit the generation of lipid peroxide in the brain, delay the occurring of spasm caused by cerebral ischemia, have the function of improving cerebral metabolism and protecting brain.

Application:

1)VINPOCETINE is a semisynthetic derivative alkaloid of vincamine, and also can be semisynthesized from tabersonine, an extract from Voacanga Africana Seed.
2)Clinical studies suggest that it facilitates cerebral metabolism by improving cerebral blood flow, increasing glucose and oxygen utilization by neurons and concentration of neurotransmitters involved in the process of memory formation.
3)Clinical studies have also shown that Vinpocetine may help to maintain healthy microcirculation in the inner vital organs of ears and eyes.
4)Research has shown that the effects of this compound go beyond mere prevention and turn it into a Powerful Memory Enhancer.

1. It has vasodilating, blood thinning, and memory-enhancing actions.
2. It acts as a cerebral stimulant and vasodilator.
3. It is used to treat arteriosclerosis.
4. It is very effective in curing dementia caused due to insufficient blood supply to the brain.
5. It interferes with cells' ability to synthesize DNA and RNA.

Vinpocetine is a kind of natural medicine extracted from small vinca flower, and belongs to the indole alkaloids. Can be synthetic now. The mechanism of its pharmacological action is to inhibit the activity of calcium dependency phosphodiesterase, increase the content of CGMP which can relax vascular smooth muscle, then relax vascular smooth muscle, and further increase cerebral blood flow; Enhance the capacity of deformation of red blood cells, reduce blood viscosity, inhibit platelet aggregation, and thus improve blood flow and microcirculation; Promote the brain tissue to absorb glucose, and promote the transformation of brain monoamine metabolism; Inhibit the increase of brain lactic acid during cerebral ischemia, increase the ATP content, increase thedegree of oxygen dissociation in hemoglobin; Increase the resistance capacity for cerebral anoxia and occurring of spasm caused by cerebral ischemia, inhibit the generation of lipid peroxide in the brain. Oral absorption effectively, reach peak at 1 h, then metabolize into Vinpocetine in the body. The half-life of plasma elimination is about 1 hour. For 4 weeks in a row, no accumulation in the body. Clinical used in cerebral infarction sequela, cerebral hemorrhage sequelae, cerebral arteriosclerosis, cerebral vasospasm, brain endarteritis caused vertigo, tinnitus, headache, dizziness, limb numbness, incontinence and other clinical manifestations, depression, anxiety, sleep disorder and other mental symptoms. Clinical experience has shown that it is effective regardless of the length of the course of the disease, and the symptom is fixed or not

COA:

Function:

1. Neurology: all kinds of cerebrovascular disease and its sequelae.
2. Cardiology: coronary heart disease, hardening of the arteries and blood clotting abnormalities, etc.
3. Eye: all kinds of views of visual impairment caused by poor circulation, etc.
4. Otolaryngology: hearing loss, tinnitus, vestibular dysfunction, etc.
5. Neurosurgery: all kinds of craniocerebral surgery back function rehabilitation.

Cerebrovascular drug. A alkaloid extracted from apocynaceae plant, Vincamine derivatives. Selectively inhibit vascular smooth muscle calcium dependency phosphodiesterase, and increase the content of cGMP, expanse cerebral vascular, which in turn increase cerebral blood flow, improve cerebral circulation, but has little effects on the cardiovascular and blood pressure. Effectively, good tolerance, less adverse reaction. Used for dizziness, headache, memory disorders, movement disorder, aphasia, hypertensive encephalopathy, etc.. Can also be used in brain blood circulation obstacle caused by mental or neurological symptoms.

Effect:

1) Inhibit the activity of calcium dependency phosphodiesterase, increase the content of cAMP which can relax vascular smooth muscle, then relax vascular smooth muscle, and further increase cerebral blood flow.
(2) Enhance the capacity of deformation of red blood cells, reduce blood viscosity, inhibit platelet aggregation, and thus improve blood flow and microcirculation.
(3) Promote the brain tissue to absorb glucose, and promote the transformation of brain monoamine metabolism.
(4) Inhibit the increase of brain lactic acid during cerebral ischemia, increase the ATP content, inhibit the generation of lipid peroxide in the brain, delay the occurring of spasm caused by cerebral ischemia, have the function of improving cerebral metabolism and protecting brain.

Dosage:

Typical doses of Vinpocetine range from 5 to 20 mg per day,but you will find 5 mg of Vinpocetine and this is typically enough for most people to achieve their desired effects.

Vinpocetine Stacking:
Vinpocetine can be an effective nootropic taken alone, but it is known to work very well in combination with other nootropics and is often found in preformulated supplements. If you prefer to make your own nootropic stack, here are some ideas for a good starting point.
Vinpocetine and Ginkgo Biloba Stack for Long-Term Cognitive Enhancement
Vinpocetine and Ginkgo Biloba act as potentiators for each other, with the combination of the increasing the overall potency and effectiveness of both. This simple stack will boost cognitive abilities, improve mood, and increase motivation and productivity.
3x per day
5 mg Vinpocetine
50 mg Ginkgo Biloba

Vinpocetine and Racetam Stack for Studying:
This stack will make the most of intensive study time; the piracetam will work with the vinpocetine to improve general cognition, the aniracetam will boost memory, and the Alpha GPC will ensure sufficient high-quality choline for transformation to acetylcholine, the "learning neurotransmitter."
2x per day
1 g Piracetam
200 mg Aniracetam
5 mg Vinpocetine
300 mg Alpha GPC

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