Product Details:

Product Name: Poly(ethylene glycol)

Synonyms: 1,2-ethanediol,homopolymer;2-ethanediyl),.alpha.-hydro-.omega.-hydroxy-Poly(oxy-1;Alcox E 160;Alcox E 30;alcoxe30;alkapolpeg-200;alkapolpeg-300;alkapolpeg-600

CAS: 25322-68-3

EINECS: 203-473-3

Product Categories: Polymers;Optimization Reagents;Protein Structural Analysis;X-Ray Crystallography;Cosmetic Ingredients & Chemicals;Gas Chromatography;Packed GC;Stationary Phases;Homobifunctional PEG;Poly(ethylene glycol) (PEG) and PEG Solutions;Poly(ethylene glycol) and Oligo(ethylene glycol);Essential Chemicals;Inorganic Salts;Materials Science;Poly(ethylene glycol) and Poly(ethylene oxide);Polymer Science;Research Essentials;Solutions and Reagents;Polydispersed PEG;polymeride

MP: 64-66 °C

BP: >250°C

Density: 1.27 g/mL at 25 °C

Vapor density: >1 (vs air)

Vapor pressure: <0.01 mm Hg ( 20 °C)

Refractive index: n20/D 1.469

Fp: 270 °C

Storage temp:. 2-8°C

Solubility H2O: 50 mg/mL, clear, colorless

Chemical Properties : Clear colorless viscous liquid

Description:

PEG is the basis of a number of laxatives. Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy. PEG is also used as an excipient in many pharmaceutical products.

When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from the blood. Polyethylene glycol has a low toxicity and is used in a variety of products.[9] The polymer is used as a lubricating coating for various surfaces in aqueous and non-aqueous environments. Polyethylene glycol is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers.

Polyethylene glycol (PEG) is a polymer made for ethylene oxide. It comes in almost any MW, from 200 to 60,000. 400 to 12,000 are the most common with 400 the most common for liquids and 2,500 for solid. (Anything over 800 to 1,000 is a solid at room temp.) It is nontoxic at any reasonable level. It is nonpolar while having lots of hydroxyl functionality. This makes it great for getting things to stay soluble in oil. Used a lot for compatibility reasons. Can also be used as a painless vehicle, instead of oil. Drawbacks include high viscosity and thermoplastic tendencies becoming more pronounced at the higher MWs. Also has mechanical properties (surface tension) that cause it to separate from oil.

Reacted with fatty acid to make different performance surfactant, PEG can be used as a pharmaceutical binder, cream and shampoo base material. Used as lubricants, binders and plasticizers, wetting agents for fiber processing, pottery, metal processing, rubber molding, and also it can be used in water soluble paints and printing inks. Used as a wetting agent in the electroplating industry. 
 

Applications:

Used in conjunction with carbon black to form a conductive composite. 1 Polymer nanospheres of poly(ethylene glycol) were used for drug delivery Polyethylene glycol 400 is suited to prepare for the soft capsule most. The polyethylene glycol 400 is a liquid and has a broad compatibility with various solvents, so it is a good solvent and solubilizer and is widely used in liquid preparations, such as the oral solution, eye drops and so on. When the vegetable oil is not suitable for a co-active ingredient carrier material, the polyethylene glycol is the preferred substitute material because the polyethylene glycol is stable and non-perishable. Besides, the injections containing polyethylene glycol are very safe and stable as long as it has been heated to 150 degrees Celsius. In addition, it can blend with PEG with high molecular weight and the mixture has a good solubility and drug compatibility.

Poly(ethylene Glycol) molecules of approximately 2000 monomers. Poly(ethylene Glycol) is used in various applications from industrial chemistry to biological chemistry. Recent research has shown PEG m aintains the ability to aid the spinal cord injury recovery process, helping the nerve impulse conduction process in animals. In rats, it has been shown to aid in the repair of severed sciatic axons, helping with nerve damage recovery. It is industrially produced as a lubricating substance for various surfaces to reduce friction. PEG is also used in the preparation of vesicle transport systems in with application towards diagnostic procedures or drug delivery methods.

H2 histamine receptor antagonist, anti-ulcer agent .

Nonionic emulsifier.

A polymer used to precipitate proteins, viruses, DNA and RNA .

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