Pharmaceuticals Raw Powder Glimepiride CAS 93479-97-1for Noninsulin-Dependent Diabetes Mellitus

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: CAS: 93479-97-1
Minimum Order Quantity: 10g
Price: Contact Us
Packaging Details: Stealth and discreet packaging
Delivery Time: Usually within 7 work days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 3000KG/Month
Product Name: Glimepiride Synonyms: 1h-pyrrole-1-carboxamide,2,5-dihydro-3-ethyl-4-methyl-n-
CAS: 93479-97-1 MF: C24H34N4O5S
MW: 490.62 Appearance: White Cyrstalline Solid
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Medicine Grade Pharmaceutical Raw Materials Glimepiride Cas 93479-97-1

 

Product Name:  Glimepiride

 

Product Details:

 

Product Name: Glimepiride
Synonyms: 1h-pyrrole-1-carboxamide,2,5-dihydro-3-ethyl-4-methyl-n-(2-(4-(4-methylcyc;glimepirid;hoe490;translohexyl)amino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-oxo;GLIMEPIRIDE;1-[[p-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea;amary;AMARYL
CAS: 93479-97-1
MF: C24H34N4O5S
MW: 490.62
MP: 212.2-214.5 °C
Storage temp: Room temp
Solubility DMSO: >10 mg/mL
Chemical Properties: White Cyrstalline Solid
Certificate: ISO 9001, USP,GMP
Usage1: anticonvulsant
Usage2: For concomitant use with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus.
Usage3: A sulfonylurea hypoglycemic agent. Used as an antidiabetic.

 

 

 

 

Description:

 

Glimepiride is used to treat high blood sugar levels caused by type 2 diabetes. It may be used alone, or in combination with insulin or another oral medicine such as metformin. In type 2 diabetes, insulin produced by the pancreas is not able to get sugar into the cells of the body where it can work properly. Using this medicine will help lower blood sugar when it is too high and help restore the way you use food to make energy. Some people can control type 2 diabetes with diet alone or diet and exercise. Following a specially planned diet and exercising will always be important when you have diabetes, even when you are taking medicines. To work properly, the amount of glimepiride you take must be balanced against the amount and type of food you eat and the amount of exercise you do. If you change your diet, your exercise, or both, you will want to test your blood sugar to find out if it is too low.

Glimepiride is a medium- to long-acting sulfonylureaantidiabetic drug. Like all sulfonylureas, glimepiride acts as an insulin secretagogue. It lowers blood sugar by stimulating the release of insulin by pancreatic beta cells and by inducing increased activity of intracellular insulin receptors.
Not all secondary sufonylureas have the same risks of hypoglycemia. Glibenclamide (glyburide) is associated with an incidence of hypoglycemia of up to 20–30%, compared to as low as 2% to 4% with glimepiride. Glibenclamide also interferes with the normal homeostatic suppression of insulin secretion in reaction to hypoglycemia, whereas glimepiride does not. Also, glibenclamide diminishes glucagon secretion in reaction to hypoglycemia, whereas glimepiride does not.

 

 

 

Application:

 

​Glimepiride (Glimer) is indicated to treat type 2 diabetes mellitus; its mode of action is to increase insulin production by the pancreas. It is not used for type 1 diabetes because in type 1 diabetes the pancreas is not able to produce insulin.Its use is contraindicated in patients with hypersensitivity to glimepiride or other sulfonylureas, and during pregnancy.
Glipizide is only part of a complete program of treatment that may also include diet, exercise, weight control, and testing your blood sugar. Follow your diet, medication, and exercise routines very closely. Changing any of these factors can affect your blood sugar levels.
Like all sulfonylureas, glimepiride acts as an insulin secretagogue.It lowers blood sugar by stimulating the release of insulin by pancreatic beta cells and by inducing increased activity of intracellular insulin receptors.

 

 

 

COA:

 

 

Test Item

 

 

Analysis Specification

 

Result

 

Description

 

 

White to off white power

white power

 

Identification

 

 

IR (similar to standard)

 

Conforms

 

Related substances by HPLC

 

 

Impurity A(Cis-isomer)

 

 

≤0.8%

 

0.13%

 

Impurity B

 

 

≤0.4%

 

0.16%

 

Impurity C

 

 

≤0.1%

 

0.05%

 

Impurity D

 

 

≤0.2%

 

0.11%

 

Any other impurity

 

 

≤0.1%

 

0.08%

 

Total impurity

 

 

≤0.5%

 

0.23%

 

Heavy metals

 

 

≤10ppm

 

<10ppm

 

Loss on drying

 

 

≤0.5%

 

0.19%

 

Sulphated ash

 

 

0.1%

 

0.07%

 

Assay(HPLC)

 

 

98.0%~102.0%

99.59%

Residual solvents

To comply the test as pre USP<467>

Complies

Conclusion

The results Conform with USP29 Standard

 

 

 

Pharmaceuticals Raw Powder Glimepiride CAS 93479-97-1for Noninsulin-Dependent Diabetes Mellitus 0

 

Our Company Advantages:

 

1, High quality with competitive price:

1) Standard: U.S Standard
2) All Purity≥99.8%
3) We are manufacturer and can provide high quality products with factory price.


2, Fast and safe delivery
1) Parcel can be sent out within 8 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99.8%
4)We provide re-ship policy.
5) We have warehouse in Australia, Canada and England, we have large amounts of stock in the warehouse, can ship to you directly from our foreign warehouse!
3, We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

 

 

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