Aprepitant CAS 170729-80-3 Pharmaceutical Grade Raw Materials White Crystals for anticholinergic

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: CAS: 170729-80-3
Minimum Order Quantity: 10g
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Delivery Time: Usually within 7 work days
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Supply Ability: 3000KG/Month
Product Name: Aprepitant Purity: 99%
CAS: 170729-80-3 MF: C23H21F7N4O3
MW: 534.4266624 Appearance: White Crystals
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Pharmaceutical Raw Material White Powder Aprepitant CAS 170729-80-3 for anticholinergic

 

Product Name: Aprepitant

 

Product Details:

 

Product Name: Aprepitant

Synonyms: 5-[2(r)-[1(r)-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3(s)-(4-fluorophenyl)morpholin-4-ylmethyl]-3,4-dihydro-2h-1,2,4-triazol-3-one;aprepitant;5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,;5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one, Emend;5-[2(R)-[1(R)-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3(S)-(4-fluorophenyl)morpholin-4-ylmethyl]-3,4-dihydro-2H-1,2,4-triazol-3-one;5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one;Emend;MK-0869
CAS: 170729-80-3
MF: C23H21F7N4O3
MW: 534.4266624

 

 

Description:

 

Aprepitant is a kind of neurokinin -1 (NK-1) receptor antagonist, is anti-cancer drugs chemotherapy vomit, by the German Merck Research success, in March 2003 the United States Food and Drug Administration approved for the treatment of chemotherapy-induced nausea and vomiting. This product has a highly selective affinity for people and has a low affinity for 5- hydroxytryptamine, dopamine and corticosteroid receptors. Aprepitant and 5-HT3 receptor inhibitors (such as ondansetron hydrochloride and dexamethasone) combined with corticosteroids, can further reduce cisplatin induced acute and delayed vomiting (or). The use of this medicine alone has a certain preventive effect.

 

 

Usage:


A novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1 Antiemetic. Usage anticholinergic .

 

 

Aprepitant CAS 170729-80-3 Pharmaceutical Grade Raw Materials White Crystals for anticholinergic 0

 

 

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Our Company Advantages:

 

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