99% Purity White Crystal Powder Raw Pharmaceutical Materials Quinine CAS: 130-95-0 For Antimalarial Drugs

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: 130-95-0
Minimum Order Quantity: 10g
Price: Contact Us
Packaging Details: Stealth And Discreet Packaging
Delivery Time: 5-8 work days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 1000kg per month
Product Name: Olaparib CAS: 130-95-0
MF: C20H25N2O2 MW: 325.4242
EINECS: 205-003-2 Appearance: White Crystalline Powder
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99% Purity White Crystal Powder Raw Pharmaceutical Materials  Quinine CAS: 130-95-0 For Antimalarial Drugs 

 

 

Product Name:

 

Product Details:

 

 

Product Name

 

Quinine

 

Other Name

 

Quinine Anhydrous

 

CAS

 

130-95-0

 

MF

 

C20H25N2O2

 

MW

 

325.4242

 

EINECS

 

205-003-2

 

Melting point

 

173-175 °C(lit.)

 

alpha

 

-172 º (c=1, EtOH)

 

storage temp.

 

Refrigerator

 

Water Solubility

 

slightly soluble

 

Type

 

Antibiotic and Antimicrobial Agents

 

Grade Standard

 

Medicine Grade

 

Usage

 

Animal Pharmaceuticals

 

Purity

 

99%

 

Sensitive

 

Light Sensitive

 

Merck

 

14,8061

 

BRN

 

91867

 

DataBase Reference

 

130-95-0( DataBase Reference)

 

EPA Substance Registry System

 

Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)-(130-95-0)

 

Appearance

 

White Crystalline Powder

 

 

Description

 

Quinine, also known as Jinji Nashuang Cream and Cinchona Alkali, is the main alkaloid in the bark of the Rubiaceae plant and its genus. The cinchona bark contains more than 20 kinds of alkaloids. Also involved in malaria are quinidine, cinchonine and cinchonidine. The whole alkaloids of the cinchona bark are used as antimalarials and antipyretics, and are called cinchona or total quinine. Quinine is chemically a quinoline and is an isomer with quinidine. White amorphous powder or crystal, odorless, very bitter taste. The melting point is 172.8 ° C, with left-handed optical, [α] D20-168 ° (ethanol). Soluble in ethanol, chloroform, benzene, ether, slightly soluble in water. The dilute sulfuric acid solution has blue fluorescence, and bromine water and excess ammonia water are added dropwise, which is emerald green. The cinchona bark powder is treated with lime and sodium hydroxide, kerosene is extracted, and dilute sulfuric acid is neutralized, and the precipitated quinine sulfate is reacted with ammonia. It is also possible to synthesize m-hydroxybenzaldehyde from α-aminoacetaldehyde as a raw material. It is used to treat and prevent various malaria, and its medicinal is its sulfate or hydrochloride.

 

Quinine is a substance that was first obtained by processing the bark of the cinchona tree, a South American native plant that has been used as a fever reducer by Native Americans for centuries. This substance has been used historically to treat malaria, along with some other medical conditions, and although a number of antimalarial drugs are on the market today, it is still used in some regions. It is also used commercially as an additive to tonic water, a soft drink that is used as a mixer for other drinks in addition to being consumed straight.

 

Application

 

An alkaloid derived from the bark of the cinchona tree.It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633.Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose.

 

Quinine was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. emeraldgo(at)hotmail.com.Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.

 

Quinine is one of the oldest antimalarial drugs. As early as the 15th century, the cinchona bark containing quinine has become a special drug widely used in the treatment of malaria. Its antimalarial effect is similar to that of chloroquine, which interferes with DNA synthesis. effect. It can inhibit the red blood cell phase of various malaria parasites and control the onset of malaria symptoms. There is also a certain killing effect on gametophytes of vivax malaria and three-day malaria. However, it has no effect on the extracellular phase of red blood cells. Its main advantage is that it is not easy to produce drug resistance. It may be that quinine and Plasmodium have different DNA binding methods than chloroquine, so there is no cross-resistance and it can be used for anti-chloroquine strains (especially Plasmodium falciparum) infection. In addition, quinine also has the effect of stimulating the uterus, inhibiting the heart muscle and relieving heat and relieving pain. In addition to medicinal use, it can be used as a detection agent for metal ions such as ruthenium and platinum in analytical chemistry, and as a precipitation agent for racemic organic acids.

 

 

 

 

COA

 

 

Test Item

 

Specifications

Result

 

Characteristics

 

White or light yellow crystalline powder

White crystalline powder

 

Infrared Spectrum Appraisal

 

Should comply

Match up the reference

 

Specific Optical Rotation

 

158 °~ 168°(Ethanol)

161°

 

Melting Point

 

173℃ ~ 178℃

174℃ ~ 177℃

 

Loss on Drying

 

≤1.0%

0.7%

 

Residue on Ignition

 

≤0.1%

0.06%

 

Heavy metal

 

<10ppm

Conforms

 

Sulphate

 

<500ppm

Conforms

 

Chloride

 

<250ppm

Conforms

 

Other Cinchona Alkaloid

 

<1.0%

0.3%

 

Assase Total Base

 

C20H24N2O2>98%

99.2%

 

Conlusion: The merchandise corresponds to Interior Quality Standard

 

 

 

 

99% Purity White Crystal Powder Raw Pharmaceutical Materials  Quinine CAS: 130-95-0 For Antimalarial Drugs 0

 

 

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4. Delivery: We have products in stock, and we will deliver them soon when your PO arrived. Meanwhile we will give you the tracking number in order to make you know the exact location of the products. We will keep track of the product until they arrive you; We choose the best courier service for you, and with the delivery around 5-7 working days.
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