Pregabalin Pharmaceutical Raw Materials CAS148553-50-8 Antiepileptic Treatment

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: 148553-50-8
Minimum Order Quantity: 10g
Price: Contact Us
Packaging Details: Stealth And Discreet Packaging
Delivery Time: 7 work days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 1000kg per month
Product Name: Pregabalin CAS: 148553-50-8
MF: 148553-50-8 EINECS: 200-659-6
Purity: 99.8% Appearance: White Crystal Powder
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White Powder 99% Pregabalin Active Pharmaceutical Ingredient CAS: 148553-50-8 For Antiepileptic and Anticonvulsant 

 

Product Details:

 

 

 

Product Name

 

Pregabalin

Synonym

 

3(S)-(AMINOMETHYL)-5-METHYLHEXANOIC ACID;(3S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID;PREGABALIN;Pregablin;3-(Aminomethyl)-5-methyl-hexanoic acid;PREDNISOLONESODIUMPHOSPHATE;(R)-Pregabalin;(S)-Pregabalin

 

 

CAS

 

148553-50-8

 

MF

 

C8H17NO2

 

MW

 

159.23

 

EINECS

 

200-659-6

 

Purity

 

99.8%

 

Appearance

 

White Crystal Powder

Usage

 

S-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.

 

 

Storage

 

Store in cool and dry area and keep away from direct sunlight

 

 

Description

 

Regabalin is described chemically as (S)-3-(aminomethyl)-5-methylhexanoic acid. The molecular formula is C8H17NO2 and the molecular weight is 159.23. Pregabalin is a white to off-white, crystalline solid with a pKa1 of 4.2 and a pKa2 of 10.6. It is freely soluble in water and both basic and acidic aqueous solutions. The log of the partition coefficient (n-octanol/0.05M phosphate buffer) at pH 7.4 is 1.35. LYRICA (pregabalin) Capsules are administered orally and are supplied as imprinted hard-shell capsules containing 25, 50, 75, 100, 150, 200, 225, and 300 mg of pregabalin, along with lactose monohydrate, cornstarch, and talc as inactive ingredients. The capsule shells contain gelatin and titanium dioxide. In addition, the orange capsule shells contain red iron oxide and the white capsule shells contain sodium lauryl sulfate and colloidal silicon dioxide. Colloidal silicon dioxide is a manufacturing aid that may or may not be present in the capsule shells. The imprinting ink contains shellac, black iron oxide, propylene glycol, and potassium hydroxide.

 

Pregabalin works by reducing the abnormal electrical activity in the brain. It is taken alongside other medicines for epilepsy. Pregabalin can also be helpful in treating the symptoms of generalised anxiety disorder (GAD), particularly if other medicines which are more often prescribed for people with this condition are not suitable. GAD is a long-term condition where anxiety is a major symptom.

Pregabalin, also known as β-isobutyl-γ-Aminobutyric acid (β-isobutyl-GABA) and sold under the trade name Lyrica among others, is a medication used to in the treatment of epilepsy, neuropathic pain, fibromyalgia and generalized anxiety disorder. Its use for epilepsy is as an add-on therapy for partial seizures with or without secondary generalization in adults.
Pregabalin is a structural analogue of the neurotransmitter GABA, consequently it belongs to the γ-Aminobutyric acid analogue class of antiepileptic drugs. Its a ion channel modulator that has analgesic, anticonvulsant, sedative, and anxiolytic properties. Pregabalin is a potent gabapentinoid and close analogue of GABOB (β-hydroxy-GABA), baclofen (β-(4-chlorophenyl)-GABA), and phenibut (β-phenyl-GABA).

 

 

Application:

Pregabalin belongs to a group of medicines known as anti-epileptic medicines, although it is prescribed for the treatment of several different conditions. You may have been prescribed it for the treatment of partial seizures, which is a type of epilepsy. A seizure is a short episode of symptoms which is caused by a burst of abnormal electrical activity in the brain. With a partial seizure, the burst of electrical activity stays in one part of the brain. Therefore, you tend to have localised or 'focal' symptoms. Pregabalin is also prescribed to treat certain types of long-lasting pain caused by damage to nerves. This type of pain, called neuropathic pain, can be caused by a number of different conditions, including diabetes (where it is called diabetic neuropathy) and shingles(where it is called postherpetic neuralgia).

 

 

 

 

COA:

 

 

Item

 

Specification

 

Result

 

Appearance

 

A white to off white powder

 

White powder

 

 

Identification

 

A. Meets the requirement

Complies

B. IR: similar to Reference Substance

Complies

 

Loss on drying

 

≤0.5%

 

0.21%

 

Specific Rotation

 

+10.0°~+13.0°

 

+10.8°

 

Related Substances

 

Any single impurity ≤0.1%
Total impurity ≤0.8%

 

0.05%
0.10%

 

Purity By HPLC R-isomer

 

≤0.15%

 

0.10%

 

Residue on ignition

 

≤0.1%

 

0.05%

Residual solvents

Isopropyl alcohol ≤5000ppm
Ethyl Acetate ≤5000ppm

 

150ppm
250ppm

 

Heavy metals

 

≤10ppm

 

Complies

 

Chlorides

 

≤0.05%

 

Complies

 

Assay

 

98%~102.0%

 

99.8%

 

Conclusion

 

Conform

 

 

 

Pregabalin Pharmaceutical Raw Materials CAS148553-50-8 Antiepileptic Treatment 0

Package and Shipping:

 

1. Mass stock: to make sure delivery promptly every day when the payment is done.


2. Rich experience: we have sophisticated and professional logistics department, which can guarantee safe and speedy delivery.


3. Professional team: well-trained and disciplined team which is professional enough to provide you a safe package. Unique ways to ship 10 grams to 20 kilograms powders (or 100ml to 30 Liter liquids) at one time to your destination.


4. Logistics information:Packing pics and tacking number are provided within 12 hours after we confirm your payment. Updated tracking information will be provided every other day just for you can hold a palm of your package.


5. Perfect after-sale service: Any questions or problems after receiving the product, please feel free to contact us. Problems would be solved immediately.

 

 

How to make order ?

 

1.Browse our online shop and tell me what product do you want to buy .

2.Contact aimee if there are some problems.

3.Our payment way is Western Union , Money Gram,T/T and Bitcoin.

4.We will send out the parcel in 24 hours after your payment .

5.And then you will get a tracking number .

 

Top reason why you choose us ?

1.Fast discreet delivery with great shipping success!
3.Pictures with your order & details!
2.We will provide you the tracking number!
3.Keep track of your goods untill the goods are sent in to your hands.
4.We confirm 99% clearance,100% resending.
6.High quality,100% pure products!
7.Delivery time approx. 4-6 business days.
8.Best, Safe and Secure services.
9.Customer support.

 

SHIPPING & DELIVERY "FAQ"

Q1. What is the minimum amount I can order at one time ?
We have NO minimum amount of order,yor order charges = your order + shipping charges.

Q2. From which transport company you can send the package?
We have worked with EMS,HKEMS,TNT,DHL,FedEX,UPS etc for years,it depends on your countrys,we comfirm that your safe & cheap dilivery.

Q3. Is it legal to purchase these products?
Since laws differ from country to country, we recommend you to contact your local FDA or customs office regarding the regulations and restrictions of your country.

Q4. How are bulk/large quantity orders shipped?
If the order is large enough to not fit in the same shipment envelope as a small sized order, we guarantee the order will be divided into the necessary amount of packages. No matter how large your order is, we reassure you the same discretion level and repackaging is used as with a small sized order.

 

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