PRL-8-53 Memory Learning Enhancer 51352-87-5 Intelligence Improvement 99% Assay

Basic Information

Product Name	PRL-8-53
Other Name	PRL-8053
CAS	51352-87-5
Purity	99%
Molecular Formula	C18H22ClNO2
Molecular Weight	319.82578
Molecular Structure

Product Description

       PRL-8-53 (chemical name Methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate) is a synthetic nootropic compound discovered in 1972 and patented in 1975 by the late Dr. Nikolaus Hansl, a neuropharmacologist at Creighton University in Omaha, Nebraska. Preliminary animal tests indicated that the compound was both safe and significantly nootropic, boosting avoidance learning in rodents with no adverse effects. But the real interest in PRL-8-53 was sparked by a 1978 study on human volunteers, which showed that a single dose of the compound could improve word retention scores by more than 200%.

PRL-8-53 Benefits

       The benefits of PRL-8-53 aren’t fully known, but it is generally considered to be a memory and learning enhancer. In the lone study with rats, taking PRL-8-53 120 - 150 minutes before a cognitive test helped drastically. Memory was tested at 24 hours after dosing and 96 hours with positive results compared to a placebo.

       Within these tests, some of the test performance improvements were in the range of 80 - 100+%, which suggests significant potential.The study separated the analysis of memory and “working memory”, which showed less improvement, but still notable.

How PRL-8-53 Works

        PRL-8-53's exact mechanisms of action are not well understood, but it is generally believed to regulate the brain's production of and response to several crucial neurotransmitters. In his reports on human and animal studies Hansl indicated that PRL-8-53 potentiates dopamine, partially restricts production of serotonin, and enhances the brain's response to acetylcholine.

Though Hansl's research report on the 1978 human study suggests those actions, it does not clearly delineate the mechanism of action.The fact that older subjects saw the most nootropic benefit from taking the drug supports the concept that dopamine modulation plays a major role in PLR-8-53's effects. Up-regulating the normal age-related lessening of dopamine production that is associated with cognitive decline could have a significant positive impact on both learning and memory.

Function

1.Enhance cognition and memory formation

2.Anxiolytic properties

3.Anti-depressive effect

4.reatment of Alzheimer's and Parkinson's disease

5.Increase coordination

6.Improves mood

7.Help fight fatigue

8.Prevent oxidation within the brain

9.Treat alcohol related brain damage

10.Prevent caffeine withdrawal symptoms

PRL-8-53 HCL Dosage 

        The only human study on PRL-8-53 was based on the ingestion of a single 5 mg dose. There is no data on the effectiveness or potential toxicity of any other dosage in humans.

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