Pramipexole Treat Parkinson 191217-81-9 USP Standard Quick Effect 99% Purity

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: 191217-81-9
Minimum Order Quantity: 10g
Price: Contact Me
Packaging Details: Disguised Package
Delivery Time: 2 Working Days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 100 KG/Month
Product Name: Pramipexole CAS: 191217-81-9
Appearance: White Powder Usage: Nervous System Drug
Shipping Method: EMS, HKEMS, FEDEX, DHL, UPS, Aramex, ETC Color: White
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Basic Information

Product Name Pramipexole
CAS 191217-81-9
Purity 99%
Molecular Formula C10H21Cl2N3OS
Molecular Weight 302.26
Molecular Structure Pramipexole Treat Parkinson 191217-81-9 USP Standard Quick Effect 99% Purity 0
Payment Method Western Union, Bank Transfer, MoneyGram, Bitcoin, Litecoin





       Pramipexole dihydrochloride monohydrate is new-generation non-ergot dopamine receptor agonist, which can avoid nervous lesion caused by long-term use of levodopa, delay levodopa treatment time, and reduce the dosage of levodopa. Moreover, the drug can be applied to D2/D3 receptors selectively, thus controlling sports-related symptoms like tremor, easing psychic symptoms and treating Parkinson’s disease.


       According to in-vitro study, Pramipexole has relatively-high specificity for D2 receptor and complete intrinsic activity, and higher affinity for D3 receptor than that for D2 and D4 receptors.


       The interaction of Pramipexole and D3 receptor and its correlation with Parkinson’s disease are indefinite. Definite mechanism for Pramipexole’s treating Parkinson’s disease is unclear. According to current opinion, it is related to dopamine receptor of activated corpus striatum. According to animal electricity physiological test, Pramipexole can influence the discharge frequency of corpus striatum neuron through activating corpus striatum and nigral dopamine receptor.




       Treating the signs and symptoms of Parkinson disease. It is also used to treat restless legs syndrome (RLS).: Pramipexole is a non-ergoline dopamine agonist indicated for treating early-stage Parkinson's disease (PD) and restless legs syndrome (RLS). It is also sometimes used off-label as a treatment for cluster headache and to counteract the problems with sexual dysfunction experienced by some users of the selective serotonin reuptake inhibitor (SSRI) antidepressants.


       Pramipexole has shown robust effects on pilot studies in a placebo-controlled proof of concept study in bipolar disorder. It is also being investigated for the treatment of clinical depression and fibromyalgia. It may also be used for other conditions as determined by your doctor.Pramipexole is a dopamine agonist. Exactly how pramipexole works is not known. It may increase the action of certain chemical receptors in the brain.


To alleviate the symptoms of Parkinson's disease: Parkinson's disease is due to the movement of brain dopaminergic neuron loss caused by dopamine deficiency, lead to patients with tremor, rigidity and bradykinesia and a series of symptoms. Hydrochloric acid highly selective effects on dopamine D2 and D3 receptor agonist, dopamine release, improve motor symptoms.


       Research on Shannon display, early Parkinson's disease patients pramipexole monotherapy after, can effectively control the motor symptoms in patients with early stage, to help maintain the ability of daily life. Pramipexole in combination with levodopa can effectively improve the ADL score and motor symptoms in patients with advanced Parkinson's disease score in patients with advanced Parkinson's disease, make life more vibrant.





Item Standard Result
Appearance White or colorless crystalline powder conforms
Salicylic acid 99.0%-100.5% min 99.56%
Melting point 158-161°C 159.5°C
Clarity and color of solution Clear and colorless conforms
Heavy Mntals 20ppm conforms
Chloride 100ppm conforms
Loss on drying 0.5% max 0.06%
Sulfate Ash 0.1%max 0.03%
Sulfate 200ppm Conforms





       The effect of Pramipexole on the D3 receptor has a strong impact on the neurological system, which is why it's used to treat Parkinson's disease and in some cases Alzheimer's disease. Through acting on the D3 receptor, Pramipexole also affects a man's sexual interest and activity. Prolactin is in part directly responsible for a man's refractory period, which refers to the time it takes to recover from sexual activity so that performance can occur again. By lowering prolactin through an increase in dopamine, Pramipexole can directly reduce the refractory period resulting in the ability to perform sexually more frequently.



Do NOT use pramipexole if

you are allergic to any ingredient in pramipexole
you are taking another medicine that has pramipexole in it

Contact your doctor or health care provider right away if any of these apply to you.




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