99% Purity Local Anesthetic Powder Procainamide Hydrochloride / Procainamide HCL CAS 614-39-1

Basic Information
Place of Origin: CHINA
Brand Name: TINGYI
Certification: GMP , ISO 9001:2008
Model Number: 614-39-1
Minimum Order Quantity: 100g
Price: 100g : 80 USD ; 1KG : 550 USD
Packaging Details: Stealth And Discreet Packaging
Delivery Time: Within 2 Working Days
Payment Terms: Bank Transfer - Bitcoin - Western Union - MoneyGram
Supply Ability: 100 KG/Month
Product Name: Procainamide Hydrochloride Other Name: Procainamide HCL
CAS: 614-39-1 MF: C13H22ClN3O
MW: 271.79 Appearance: White Powder
Purity: 99% Usage: Local Anesthetic
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                                 99% Purity Local Anesthetic Powder Procainamide Hydrochloride / Procainamide HCL CAS 614-39-1 0


Procainamide Hydrochloride



Basic Details:
Product Name: Procainamide Hydrochloride
CAS: 614-39-1
MF: C13H22ClN3O
MW: 271.79
EINECS: 210-381-7

Chemical Properties
Melting point: 165-168 °C
density: 1.2027 (rough estimate)
refractive index: 1.6330 (estimate)
storage temp: 2-8°C
solubility H2O: soluble1g/10 mL, clear, greenish-yellow
appearance: White to slightly yellow
Water Solubility: soluble
Sensitive: Light Sensitive/Air Sensitive
Uses: Class I antiarrhythmic


Definition ChEBI:

A hydrochloride which has procainamide as the amino component.
General Description Procainamide hydrochloride,p-amino-N-[2-(diethylamino)ethyl]benzamidemonohydrochloride, procainamidium chloride (Pronestyl,Procan SR), has emerged as a major antiarrhythmic drug. Itwas developed in the course of research for compoundsstructurally similar to procaine, which had limited effectas an antiarrhythmic agent because of its central nervoussystem (CNS) side effects and short-lived action causedby rapid hydrolysis of its ester linkage by plasma esterases.Because of its amide structure, procainamide hydrochlorideis also more stable in water than is procaine.


Aqueoussolutions of procainamide hydrochloride have a pH ofabout 5.5. A kinetic study of the acid-catalyzed hydrolysisof procainamide hydrochloride showed it to be unusuallystable to hydrolysis in the pH range 2 to 7, even at elevatedtemperatures.

Clinical Use Procainamide hydrochloride is metabolized through theaction of N-acetyltransferase. The product of enzymaticmetabolism of procainamide hydrochloride is N-acetylprocainamide(NAPA), which possesses only 25% of the activityof the parent compound.26 A study of the disposition ofprocainamide hydrochloride showed that 50% of the drugwas excreted unchanged in the urine, with 7% to 24% recoveredas NAPA.28,29 Unlike quinidine, procainamide hydrochlorideis bound only minimally to plasma proteins.Between 75% and 95% of the drug is absorbed from the gastrointestinaltract. Plasma levels appear 20 to 30 minutesafter administration and peak in about 1 hour.30Procainamide hydrochloride appears to have all of theelectrophysiological effects of quinidine.


It diminishesautomaticity, decreases conduction velocity, and increasesaction potential duration and, thereby, the refractory periodof myocardial tissue. Clinicians have favored the use of procainamidehydrochloride for ventricular tachycardias andquinidine for atrial arrhythmias, even though the two drugsare effective in either type of disorder.





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Generally,for small quantity product,the product will be shipped by courier.For bulk goods,usually you will receive the product within 15 working days.The rate of passing customs is more than 90%.

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