Natural Male Enhancement Supplements Sildenafil Citrate Raw Powder Strong Effect CAS 171599-83-0

Male Enhancement Sildenafil Citrate () Raw Powder / Strong Effect
 

Quick Details:

Product Name: Sildenafil citrate
 

CAS: 171599-83-0
 

MF: C28H38N6O11S
 

MW: 666.7
 

MP: 187-189°C
 

storage temp: Desiccate at RT
 

Appearance: White Powder

 
Description:
 
Sildenafil citrate is the raw material of , treats erectile dys function and
 
works by relaxing muscles and increases blood flow to particular areas of the body (in this
 
case, the penis, specifically). Its effects last up to four hours. The most common side
 
effects of are headache, facial flushing, and upset stomach. Rarely, blurred vision,
 
or sensitivity to light may briefly occur.
 
 
As well as treating impotence, Sildenafil Citrate can also be effective in treating Pulmonary
 
Arterial Hypertension (PAH). Similarly to how it acts to relax muscles of the penis, it
 
relaxes arterial walls; therefore, reducing resistance and pressure in the arteries.
 
 
Sildenafil Citrate is solely active in relaxing muscles and increasing blood flow to the
 
heart, lungs and penis due to PDE-5, yet vasodilation is not increased in other parts of the
 
body.
 

 
Lab Test Result:
 

 
 

Application:
 
Sildenafil citrate, sold as , Revatio and under various other trade names, is a drug
 
used to treat erectile dysfunction and pulmonary arterial hypertension (PAH).
 
used in the treatment of penile erectile dysfunction (ED).
 
 
The primary indication of sildenafil is treatment of erectile dysfunction (inability to
 
sustain a satisfactory erection to complete intercourse). Its use is now standard treatment
 
for erectile dysfunction in all settings, including diabetes.
 
 
People on antidepressants may experience sexual dysfunction, either as a result of their
 
illness or as a result of their treatment.
 

 
Mechanism Of Action:
 
The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in the
 
corpus cavernosum during sexual stimulation. NO then activates the enzyme guanylate

cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP),

producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood.
 
 
Sildenafil enhances the effect of NO by inhibiting phosphodiesterase type 5 (PDE5), which is
 
responsible for degradation of cGMP in the corpus cavernosum. Sildenafil has no direct

elaxant effect on isolated human corpus cavernosum. When sexual stimulation causes local

release of NO, inhibition of PDE5 by sildenafil causes increased levels of cGMP in the corpus

cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus

cavernosum. Sildenafil at recommended doses has no effect in the absence of sexual

stimulation.