Highly Recommended Sex Drug Avanafil Raw Powder


Description:

Avanafil is a PDE5 inhibitor approved for erectile dysfunction by FDA . Avanafil acts by inhibiting

a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily

in the corpus cavernosum penis, as well as the retina. Other similar drugs are tadalafil and

vardenafil. The advantage of avanafil is that it has very fast onset of action compared with other

PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 3045

minutes.

Usage:
 

It is a development of the phosphodiesterase type 5 inhibitors, for the treatment of male sexual

dysfunction, at present in the America, EU and Japan have completed phase II clinical trials,

phase III clinical trials will start. The product is composed of Japanese Tanabe Pharma Company

and VIVUS company development. In addition to oral dosage forms, VIVUS company is also

developing Avanafil urethral administration, for not responding to oral dosage forms of patients.
 

Avanafil is a potent, highly selective phosphodiesterase 5 inhibitor, in vitro experiments showed

that the selectivity of phosphodiesterase 5 stronger than sildenafil. The compound dear

compliance weak against other phosphodiesterase, and effect of adenosine receptor

decreased, suggesting that the cardiovascular effects of avanafil should be weaker than

sildenafil. Pre clinical study showed that avanafil and organic nitrate drugs taken in combination

to reduce its on blood pressure was significantly weaker than sildenafil and nitrate drugs with

clothes. Moreover, avanafil inhibition of phosphodiesterase 6 is very weak, the relevant visual

disturbance suppression may the enzyme phosphodiesterase 5 inhibitor induced and other.

Dosage :
 

For most individuals, the recommended starting dose of avanafil is 100 mg per day taken about

30 minutes before sexual activity. Depending on the adequacy of the response or side effects,

the dose may be increased to 200 mg or decreased to 50 mg a day. Individuals who are taking

medications that moderately increase the blood levels of avanafil should not exceed a total dose

of 50 mg in 24 hours.

Lab Test Result:

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