99.3% Purity Tauroursodeoxycholic Acid Powder Tudca Pharmaceutical Grade Raw Materials

99.3% Medicine Grade Tauroursodeoxycholic Acid / TUDCA Powder
 

Description:
 
Tauroursodeoxycholic acid is a bile acid also known as TUDCA formed in the liver by conjugation
 
of deoxycholate with taurine, usually as the sodium salt. TUDCA is able to prevent apoptosis and
 
protect mitochondria from cellular elements that would otherwise interfere with energy production.
 
One of these elements is a protein called Bax. TUDCA plays an important role in preventing Bax
 
from being transported to the mitochondria. Bile acids are steroid acids found predominantly in
 
bile of mammals.
 
 
The distinction between different bile acids is minute, depends only on presence or absence of
 
hydroxyl groups on positions 3, 7, and 12. Bile acids are physiological detergents that facilitate
 
excretion, absorption, and transport of fats and sterols in the intestine and liver. Bile acids are
 
also steroidal amphipathic molecules derived from the catabolism of cholesterol. They modulate
 
bile flow and lipid secretion, are essential for the absorption of dietary fats and vitamins, and
 
have been implicated in the regulation of all the key enzymes involved in cholesterol homeostasis.
 
Bile acids recirculate through the liver, bile ducts, small intestine and portal vein to form an
 
enterohepatic circuit. They exist as anions at physiological pH and, consequently, require a
 
carrier for transport across the membranes of the enterohepatic tissues. The unique detergent
 
properties of bile acids are essential for the digestion and intestinal absorption of hydrophobic
 
nutrients.
 
 
Benefits:
 
TUDCA has significant protective properties for many organs throughout the human body.It
 
protects skeletal muscles and other organs, particularly the liver, by increasing insulin sensitivity
 
to appropriate levels.TUDCA has shown to do this by protecting endoplasm reticulum from
 
stress.
 
 
Insulin resistance plays a large part in health issues related to excess fat.TUDCA is used for
 
many liver healing and immune-improving purposes, and also is used to support a healthy
 
gallbladder.
 
 
This dietary supplement may have some powerful neuroprotective properties, and is indicated in
 
the protection of cells from destruction.To protect cells, TUDCA modulates certain cell cycle
 
effector genes.While these signaling pathways have been identified, the full role of TUDCA in cell
 
maintenance is not yet fully understood.
 
 
By protecting cells from destruction, TUDCA has proven to be effective in helping eye's maintain
 
cones and rods.This photoreceptor protection can go a long way in promoting healthy vision.
 
TUDCA is also linked to increased antioxidant activity.
 
 

 
 
Dosage:
 
Recommended dosage, active amounts, other details 10-13mg daily has once been shown to
 
improve liver regenesis rates in a clinically ill population, and may be the lowest estimate of an
 
active oral dose. When looking at improving bile salt composition, a dose around 15-20mg/kg
 
bodyweight TUDCA seems best according to one study.Benefits have been seen at 1,750mg
 
daily for muscle and liver insulin sensitivity, which is the highest dose used for treatment of fatty
 
liver disease.