Place of Origin: | CHINA |
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Brand Name: | TINGYI |
Certification: | GMP , ISO 9001:2008 |
Model Number: | CAS: 59122-46-2 |
Minimum Order Quantity: | 10g |
Price: | Contact Us |
Packaging Details: | Stealth And Discreet Packaging |
Delivery Time: | Within 7 Working Days |
Payment Terms: | Bank Transfer - Bitcoin - Western Union - MoneyGram |
Supply Ability: | 300 KG/Month |
Product Name: | Misoprostol | Other Name: | CYTOTEC |
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MF: | C22H38O5 | MW: | 382.54 |
MP: | 261-263°C | Storage Temp: | 20°C |
Appearance: | White Solid | ||
High Light: | pharmaceutical anabolic steroids,pharmaceutical fine chemicals |
99.05% High Purity Pharmaceutical Intermediate Misoprostol White Solid
Description:
Misoprostol is a medication used to start labor, induce abortions, prevent and treat stomach
ulcers, and treat postpartum bleeding due to insufficient contraction of the uterus. For abortions it
is used with mifepristone or methotrexate. It is a synthetic prostaglandin E1 (PGE1).
Common side effects include diarrhea and abdominal pain. It is pregnancy category X meaning
that it is known to result in negative fetal outcomes if taken during pregnancy. Uterine rupture may
occur.
Usage:
Misoprostol acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein
coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular
cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell.
Because other classes of drugs, especially H2-receptor antagonists and proton pump inhibitors,
are more effective for the treatment of acute peptic ulcers, misoprostol is only indicated for use by
people who are both taking NSAIDs and are at high risk for NSAID-induced ulcers, including the
elderly and people with ulcer complications. Misoprostol is sometimes coprescribed with
NSAIDs to prevent their common adverse effect of gastric ulceration.
Misoprostol has other protective actions, but is only clinically effective at doses high enough to
reduce gastric acid secretion. For instance, at lower doses, misoprostol may stimulate increased
secretion of the protective mucus that lines the gastrointestinal tract and increase mucosal blood
flow, thereby increasing mucosal integrity. However, these effects are not pronounced enough to
warrant prescription of misoprostol at doses lower than those needed to achieve gastric acid
suppression.
However, even in the treatment of NSAID-induced ulcers, omeprazole proved to be at least as
effective as misoprostol,but was significantly better tolerated, so misoprostol should not be
considered a first-line treatment. Misoprostol-induced diarrhea and the need for multiple daily
doses are the main issues impairing compliance with therapy.
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