Place of Origin: | CHINA |
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Brand Name: | TINGYI |
Certification: | GMP , ISO 9001:2008 |
Model Number: | CAS: 721-50-6 |
Minimum Order Quantity: | 100g |
Price: | Contact Us |
Packaging Details: | Stealth And Discreet Packaging |
Delivery Time: | Within 7 Working Days |
Payment Terms: | Bank Transfer - Bitcoin - Western Union - MoneyGram |
Supply Ability: | 1000 KG/Month |
Product Name: | Prilocaine | MF: | C13H20N2O |
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MW: | 220.31 | EINECS: | 211-957-0 |
Melting Point: | 37-38 ℃ | Appearance: | White Crystal |
High Light: | pain killer powder,pure benzocaine powder |
99% USP Effective Local Anesthetic Raw Material Prilocaine White Crystal
Description:
Prilocaine belongs to amide local anesthetic drug with its anesthesia intensity and speed being
similar as lidocaine but with a longer duration period and weaker effect on vasodilation. It has a
lower toxicity than lidocaine. It is clinically for local anesthesia, especially suitable for treating
patients who are not allowed to use adrenaline.
[Pharmacological] its 3% solution has a similar local anesthesia efficacy as the anesthesia drug
of 2% lidocaine together with adrenaline. It has a slow onset time which lasts about 6~7min and
the duration time of about 1.5~2h. It has a strong penetration capability through mucous
membranes. Adrenaline has a slightly prolonged duration of action. PPB is 55% and T1/2 of
about 1.5h. It is subject to liver metabolism with its metabolites nitroso toluidine being able to
oxidize hemoglobin to form methemoglobin. It can be transported to the fetus through the
placenta.
[Adverse reactions] once the usage amount exceeds 600mg, methaemoglobinaemia can occur
with cyanosis, tachycardia, headache, dizziness and weakness occurring.
[Note] patients of anemia, congenital or acquired methaemoglobinaemia, respiratory failure or
heart failure and hypoxic patients should be disabled. It is forbidden for applied to obstetric
anesthesia.
[Usage and dosage] infiltration anesthesia: 0.5% to 1% solution with the duration of action of 1 to
1.5 hours.
Nerve blocking anesthesia: use 1% to 2% solution with the duration of action being 2-3 hours.
Epidural anesthesia: use10 to 30 mL of 1.5%~1% solution with the duration of action of 2.5 to 3.5
hours. Use a maximum dose of 600 mg.
Chemical Properties It is a kind of needle-like crystals with the melting point being 37-38 ℃ and
the boiling point being 159-162 ℃ (0.133kPa), and refractive index (nD20) being 1.5299. Its
hydrochloride ([1786-81-8]) is a white crystalline powder. The Melting point is 167-168 ℃. It is
soluble in water and ethanol, slightly soluble in chloroform. It has sour taste and bitter taste and is
odorless.
Uses It is a kind of local anesthetic drug. The product has better efficacy than procaine and the
local anesthesia intensity and speed being similar as lidocaine but with longer duration time and
less toxicity as well as smaller accumulation effect. It is suitable for epidural anesthesia,
conduction anesthesia and infiltration anesthesia.
Local Anesthetic Powder
|
|
Benzocaine |
Prilocaine |
Benzocaine HCL |
Procaine |
Bupivacaine HCL |
Procaine HCL |
Levobupivacaine HCL |
Propitocaine HCL |
Lidocaine |
Ropivacaine HCL |
Lidocaine HCL |
Tetracaine |
Pramoxine HCL |
Tetracaine HCL |