CAS 51-05-8 Local Anesthetic Powder Novocain Procaine Hydrochloride / Procaine HCL

Local Anesthetic Powder Procaine Hydrochloride / Procaine HCL CAS 51-05-8 Good For Pain Relieve

Abstract

Procaine hydrochloride, also called Novocain, or , synthetic organic compound used in medicine as a local anesthetic. Introduced in 1905 under the trade name , it became the first and best-known substitute for in local anesthesia.

Generally used in a 1 to 10 percent saline solution, procaine hydrochloride is administered by injection for infiltration (area flooding as in dental anesthesia), nerve-block, spinal, and caudal anesthesia. Unlike , procaine is not toxic, addicting, or irritating. It has been displaced somewhat by the chemically related drugs lidocaine and mepivacaine, which produce prompter, more intense anesthesia.

Procaine HCL is actually a very simple combination of two B vitamins, PAPA (P-aminobenzoic acid) and DEAE (diethylaminoethanol) buffered and stabilized with benzoic acid and potassium metabisulfite for more effectiveness inside the body. Procaine hydrochloride is a compound combination of PABA and DEAE, a vitaminic substance first synthesized in 1905 by a German chemist, Dr. Albert Einhorn, who was looking for a simple, non-addictive anesthetic.

For years procaine was used as a simple anesthetic, but soon researchers began to notice other curative powers of this substance. Interest in experimentation ran so high that between 1930 and 1951, over 165 reports were published on the effects of procaine in the treatment of a variety of conditions including arthritis, neuralgia, itching, peptic ulcer, asthma and hypertension. In the late 1940's three French physicians - Drs. Ghali, Boudon, and Guoit - found that procaine hydrochloride helped relieve suffering from asthma attacks. Dr. Rene Leriche discovered that procaine injections were helpful in treating certain forms of arthritis, arteritis, and blood clots in the limbs.