| Place of Origin: | CHINA |
|---|---|
| Brand Name: | TINGYI |
| Certification: | GMP , ISO 9001:2008 |
| Model Number: | 27262-48-2 |
| Minimum Order Quantity: | Negotiation |
| Price: | Contact Us |
| Packaging Details: | Stealth And Discreet Packaging |
| Delivery Time: | Within 7 Working Days |
| Payment Terms: | Bank Transfer - Bitcoin - Western Union - MoneyGram |
| Supply Ability: | 100 KG/Month |
| Product Name: | Levobupivacaine Hydrochloride | Other Name: | Levobupivacaine HCL |
|---|---|---|---|
| MF: | C18H29ClN2O | MW: | 324.8887 |
| Appearance: | White Crystalline Powder | Shipping Method: | EMS, HKEMS, FEDEX, DHL, UPS, Aramex, ETC |
| High Light: | local anesthesia drugs,pure benzocaine powder |
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Chirocaine Anti Pain Raw Powder Levobupivacaine Hydrochloride / Levobupivacaine HCL CAS 27262-48-2
Abstract
Levobupivacaine hydrochloride is commonly marketed by Abbott under the trade name Chirocaine.Bupivacaine is an amide-type local anaesthetic.Although it blocks neuro transmission,its membrane stabilising action also affects the myocardium.This can cause fatal cardiotoxicity.As bupivacaine is widely used in surgery and obstetrics,attempts have been made to develop a safer long-acting local anaesthetic.
The bupivacaine molecule is a racemic compound.Levobupivacaine is the S-enantiomer of bupivacaine and is thought to have less cardiotoxic potential than the R-enantiomer.The pharmacokinetic parameters of levobupivacaine are similar to those of bupivacaine.
Levobupivacaine has been studied in surgical anaesthesia and for pain management.It can be used for local infiltration,epidural,intrathecal and peripheral nerve blocks.For epidural analgesia it can be given with clonidine.Double-blind comparisons of levobupivacaine and bupivacaine show that their anaesthetic effects are similar.
COA
| Test Items | Specification | Test Results |
| Description | White or almost white crystalline powder | White crystalline powder |
| Melting Point | 191.0~193.0ºC | 192ºC |
| Loss of drying | ≤1.0% | 0.5% |
| Heavy Metal | ≤20ppm | 15ppm |
| TLC | Only one spot | Only one spot |
| Assay | ≥99.5% | 99.91% |
| Conclusion | It complies with the USP 32. | |
Application
Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by Abbott under the trade name Chirocaine. Bupivacaine is an amide-type local anaesthetic. Although it blocks neuro transmission, its membrane stabilising action also affects the myocardium. This can cause fatal cardiotoxicity. As bupivacaine is widely used in surgery and obstetrics, attempts have been made to develop a safer long-acting local anaesthetic.
The bupivacaine molecule is a racemic compound. Levobupivacaine is the S-enantiomer of bupivacaine and is thought to have less cardiotoxic potential than the R-enantiomer. The pharmacokinetic parameters of levobupivacaine are similar to those of bupivacaine.
Levobupivacaine has been studied in surgical anaesthesia and for pain management. It can be used for local infiltration, epidural, intrathecal and peripheral nerve blocks. For epidural analgesia it can be given with clonidine. Double-blind comparisons of levobupivacaine and bupivacaine show that their anaesthetic effects are similar.
Related Local Anesthetic API
| Benzocaine | CAS:94-09-7 |
| Benzocaine hydrochloride | CAS: 23239-88-5 |
| Lidocaine Base | CAS:137-58-6 |
| Lidocaine Hydrochloride | CAS:73-78-9 |
| Procaine hydrochloride | CAS:51-05-8 |
| Tetracaine hydrochloride | CAS:136-47-0 |
| Articaine hydrochloride | CAS:23964-57-0 |
| Propitocaine hydrochloride | CAS:1786-81-8 |
| Levobupivacaine hydrochloride | CAS:27262-48-2 |
| Proparacaine hydrochloride | CAS: 5875-06-9 |
| Ropivacaine hydrochloride | CAS: 132112-35-7 |
| Ropivacaine mesylate | CAS:854056-07-8 |
| Bupivacaine hydrochloride | CAS: 14252-80-3 |
| Dibucaine | CAS:85-79-0 |
| Prilocaine | CAS:721-50-6 |
| Proparacaine | CAS:298-50-0 |
| Articaine | CAS:23964-58-1 |
| Bupivacaine | CAS:2180-92-9 |
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