| Place of Origin: | CHINA |
|---|---|
| Brand Name: | TINGYI |
| Certification: | GMP , ISO 9001:2008 |
| Model Number: | 318-98-9 |
| Minimum Order Quantity: | Negotiation |
| Price: | Contact Us |
| Packaging Details: | Stealth And Discreet Packaging |
| Delivery Time: | Within 7 Working Days |
| Payment Terms: | Bank Transfer - Bitcoin - Western Union - MoneyGram |
| Supply Ability: | 100 KG/Month |
| Product Name: | Propranolol Hydrochloride | Other Name: | Propranolole HCl |
|---|---|---|---|
| Appearance: | White Powder | MF: | C16h22clno2 |
| MW: | 295.8 | Shipping Method: | EMS, HKEMS, FEDEX, DHL, UPS, Aramex, ETC |
| High Light: | pharmaceutical active ingredients,pharmaceutical fine chemicals |
||
Raw Steroid Powder Pharmaceutical Intermediate Propranolol Hydrochloride /Propranolole HCl CAS 318-98-9
Description
Propranolol is a nonselective beta-adrenergic receptor blocking agent possessing no other autonomic nervous system activity. It specifically competes with beta-adrenergic receptor stimulating agents for available receptor sites. When access to beta-receptor sites is blocked by propranolol, chronotropic, inotropic, and vasodilator responses to beta-adrenergic stimulation are decreased proportionately.
Specification
| Items | Specifications | Results |
| Appearance | A white or almost white powder | Conforms |
| Solubility | Soluble in water and in ethanol (96%) | Conforms |
| Identification | ||
| A | Melting point : 163°C~166°C | 164.0~164.5°C |
| B | Examine by infrared absorption spectrophotometry, comparing with the spectrum obtained with propranolol hydrochloride CRS. | Conforms |
| C | Examine by thin-layer chromatography. The principal spot in the chromatogram obtained with the test solution is similar in position, colour and size to the principal spot in the chromatogram obtained with the reference solution. | Conforms |
| D | It gives reaction(a) of chlorides | Conforms |
| Tests | ||
| Appearance of solution | The solution is clear and not more intensely coloured than intensity 6 of the range of reference solutions of the most appropriate colour | Conforms |
| Acidity or alkalinity | Add 0.1ml of methyl red solution R and 0.2 ml of 0.01M hydrochloric acid, the solution is red. Add 0.4ml of 0.01 M sodium hydroxide. The solution is yellow. | Conforms |
| Related substances | Any impurity NMT 0.1% | 0.03% |
| The sum of all impurities NMT 0.4% | 0.21% | |
| Heavy metals | NMT 20ppm | Conforms |
| Loss on drying | NMT 0.5% | 0.11% |
| Sulphated ash | NMT 0.1% | 0.08% |
| Residual solvents | A: ethanol: NMT 5000ppm B: Xylene: NMT 2170ppm |
Conforms Conforms |
| Assay | 99.0%~101.0% | 99.3% |
| Conclusion: conform to EP7.0 | ||
Application
Propranolol is indicated for the management of various conditions including: Hypertension; Angina pectoris; Tachyarrhythmias; Myocardial infarction; Control of tachycardia/tremor associated with anxiety, hyperthyroidism or lithium therapy; Essential tremor; Sex Change; Migraine prophylaxis; Cluster headaches prophylaxis; Tension headache (Off label use); Shaky hands.
Advantage
1, High quality with competitive price:
(1)Standard: Enterprise Standard
(2)All Purity≥ 99%
(3)We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
(1)Parcel can be sent out in 24 hours after payment. Tracking number available
(2)Secure and discreet shipment. Various transportation methods for your choice.
(3)Customs pass rate ≥ 99%
(4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.
3, We have clients throughout the world.
(1)Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
(2)Market feedback and goods feedback will be appreciated, meeting customer's requirement is our responsibility.
(3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
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